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Western medicine composition for treatment of gout

A composition and technology of western medicine, applied in the field of western medicine composition for the treatment of gout, can solve problems such as poor therapeutic effect, hyperuricemia, and general drug efficacy, and achieve the effect of reasonable drug combination, treatment of gout, and fast onset of effect

Inactive Publication Date: 2018-06-01
马艳红
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In addition, hyperuricemia may also occur in kidney transplant patients taking immunosuppressive agents for a long time, which may be related to the inhibition of renal tubular excretion of uric acid by immunosuppressants
[0004] Now there are many drugs for the treatment of gout, but most of the drugs have mediocre efficacy, relatively large side effects, and poor therapeutic effect. With the development of medical technology, traditional drugs can no longer meet the current use requirements

Method used

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Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0022] The preparation method of the sodium bicarbonate is as follows: put the sodium carbonate on the reaction bed, mix well with water, blow carbon dioxide from the lower part, dry, pulverize and pack after carbonization to obtain the finished product.

[0023] The preparation method of the magnesium oxide is as follows: dolomite is calcined, digested and carbonized to obtain basic magnesium carbonate, and then subjected to thermal decomposition, calcined, pulverized and winnowed to obtain light magnesium oxide.

[0024] The production method of Sulpyrine is as follows: take 4-aminoantipyrine (AA) as raw material, generate 4-formylaminoantipyrine (FAA) through formylation, and then generate 4-aminoantipyrine (FAA) through methylation. Formylmethylaminoantipyrine (FMAA) is hydrolyzed to 4-methylaminoantipyrine (MAA), and finally produced through condensation reaction.

[0025] The eugenol is natural eugenol, which mainly uses the volatile oil obtained by distillation from the...

Embodiment 1

[0031] A western medicine composition for treating gout, comprising the following raw materials by weight: 0.3 grams of sucralfate per capsule, 0.05 grams of sodium bicarbonate per capsule, 0.05 grams of magnesium oxide per capsule, and 0.2 grams of bromobenzoylfuran capsules, analgin 0.5g per capsule, ketoprofen 1.0g per capsule, prednisone acetate 0.05g per capsule, eugenol 0.07g per capsule, naproxen 0.08g per capsule.

[0032] The western medicine composition of the present invention is an oral dosage form. The western medicine composition of the present invention also includes hydroxymethyl chitosan. The adult dosage of the active ingredient of the western medicine composition described in the western medicine composition of the present invention is 0.44 mg / kg / day.

[0033] The medicine combination of the invention is reasonable, and various kinds of raw materials are matched reasonably, can effectively treat gout, has fast onset of action, and short course of treatment,...

Embodiment 2

[0035] A western medicine composition for treating gout, comprising the following raw materials by weight: 0.2 grams per capsule of sucralfate, 0.07 grams per capsule of sodium bicarbonate, 0.08 grams per capsule of magnesium oxide, 0.1 grams per capsule of bromobenzoylbenzofuran Analgin 0.8g per capsule, Ketoprofen 0.8g per capsule, Prednisone Acetate 0.08g per capsule, Eugenol 0.1g per capsule, Naproxen 0.1g per capsule.

[0036] The western medicine composition of the present invention is an oral dosage form. The western medicine composition of the present invention also includes hydroxymethyl chitosan. The adult dosage of the active ingredient of the western medicine composition described in the western medicine composition of the present invention is 0.44 mg / kg / day.

[0037] The medicine combination of the invention is reasonable, and various kinds of raw materials are matched reasonably, can effectively treat gout, has fast onset of action, and short course of treatment...

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PUM

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Abstract

The invention discloses a western medicine composition for treatment of gout. The western medicine composition is prepared from, by weight in per pill, 0.2-0.5 g of sucralfate, 0.01-0.2 g of NaHCO3, 0.01-0.1 g of MgO, 0.1-0.3 g of benzbromarone, 0.2-1.5 g of analginum, 0.1-2.0 g of ketoprofen, 0.05-0.1 g of prednisone acetate, 0.05-0.2 g of eugenol and 0.05-0.1 g of naproxen. The western medicinecomposition has reasonable medicine combination and raw material coordination, can effectively treat the gout, is quick to work and is short in treatment course, and satisfies use demands at present.

Description

technical field [0001] The invention relates to the technical field of western medicine, in particular to a western medicine composition for treating gout. Background technique [0002] Gout is a crystal-associated arthropathy caused by the deposition of monosodium urate (MSU), which is directly related to hyperuricemia caused by purine metabolic disorders and / or decreased uric acid excretion, especially acute characteristic arthritis and Chronic tophi diseases mainly include acute onset arthritis, tophi formation, tophi chronic arthritis, urate nephropathy and uric acid urolithiasis. In severe cases, joint disability and renal insufficiency may occur. Gout is often accompanied by abdominal obesity, hyperlipidemia, hypertension, type 2 diabetes and cardiovascular disease. [0003] The most important biochemical basis of gout is hyperuricemia. A normal adult produces about 750 mg of uric acid per day, of which 80% is endogenous and 20% is exogenous uric acid. These uric aci...

Claims

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Application Information

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IPC IPC(8): A61K33/08A61P19/06A61K33/00A61K31/7024A61K31/343A61K31/4152A61K31/192A61K31/573A61K31/085
CPCA61K31/085A61K31/192A61K31/343A61K31/4152A61K31/573A61K31/7024A61K33/00A61K33/08A61K2300/00
Inventor 马艳红谭凤莲刘芳李瑞芳孟建刘崇峰
Owner 马艳红
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