Mammary gland hyperplasia treatment traditional Chinese medicine transdermal patch with effect of promoting blood circulation to remove meridian obstruction

A transdermal patch, promoting blood circulation and dredging collaterals, which is applied in heating appliances for therapeutic treatment, cooling appliances for therapeutic treatment, magnetic fields generated by permanent magnets, etc., which can solve the problem of difficult release of active ingredients and decrease of biological potency of drugs , affect the clinical effect and other issues, achieve the effect of lasting blood concentration, promote transdermal absorption, reduce toxicity and side effects

Inactive Publication Date: 2018-08-17
福建鑫美源生物医药工程有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] At present, the medicinal ingredients in the medicinal patches for mammary gland hyperplasia on the market are often directly crushed Chinese medicinal materials and packaged for use. In this way, the

Method used

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  • Mammary gland hyperplasia treatment traditional Chinese medicine transdermal patch with effect of promoting blood circulation to remove meridian obstruction
  • Mammary gland hyperplasia treatment traditional Chinese medicine transdermal patch with effect of promoting blood circulation to remove meridian obstruction

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0033] The drug layer in the traditional Chinese medicine transdermal patch is made by compounding Chinese medicine components and polymer materials; the preparation method of the drug layer specifically includes the following steps:

[0034] 1) In terms of parts by weight, take 5 parts of deerbite, 6 parts of flea, 3 parts of peach kernel, 2 parts of safflower, 3 parts of frankincense, 3 parts of myrrh, 3 parts of madder, 8 parts of sunflower, and Bupleurum 3 parts, 2 parts of Citrus aurantium, 4 parts of dandelion, 3 parts of trigonum, 3 parts of curcuma, 2 parts of Leulu, 2 parts of Shanzi mushroom, 3 parts of rhubarb, 2 parts of dried ginger, 3 parts of centipede, 1 part of green skin, After pulverizing 4 parts of scorpion, 4 parts of leech, 1 part of Artemisia indica, 1 part of Gentiana ferulica, 2 parts of ferulicum and 4 parts of dried blood, add 3 times its weight of 85wt% ethanol for reflux extraction twice, each time for 1 hour, Combining the two extracts, filtering ...

Embodiment 2

[0038] The drug layer in the traditional Chinese medicine transdermal patch is made by compounding Chinese medicine components and polymer materials; the preparation method of the drug layer specifically includes the following steps:

[0039] 1) In terms of parts by weight, take 7 parts of deerbite, 10 parts of flea, 5 parts of peach kernel, 4 parts of safflower, 5 parts of frankincense, 5 parts of myrrh, 5 parts of madder, 9 parts of sunflower, and Bupleurum 5 parts, 4 parts of Citrus aurantium, 8 parts of dandelion, 5 parts of trigonum, 5 parts of Curcuma, 4 parts of Leulu, 4 parts of Shanzi mushroom, 5 parts of rhubarb, 4 parts of dried ginger, 5 parts of centipede, 3 parts of green skin, After crushing 6 parts of scorpion, 6 parts of leech, 3 parts of Artemisia spp., 3 parts of Gentiana, 4 parts of ferulicum and 8 parts of dried blood, add 5 times its weight of 85wt% ethanol to reflux and extract twice, each time for 1 hour, Combining the two extracts, filtering and recove...

Embodiment 3

[0043] The drug layer in the traditional Chinese medicine transdermal patch is made by compounding Chinese medicine components and polymer materials; the preparation method of the drug layer specifically includes the following steps:

[0044] 1) In terms of parts by weight, take 6 parts of deerbite, 8 parts of flea, 4 parts of peach kernel, 3 parts of safflower, 4 parts of frankincense, 4 parts of myrrh, 4 parts of madder, 10 parts of sunflower, and Bupleurum 4 parts, 3 parts of Citrus aurantium, 6 parts of dandelion, 4 parts of trigonum, 4 parts of Curcuma, 3 parts of Leulu, 3 parts of Shanzi mushroom, 4 parts of rhubarb, 3 parts of dried ginger, 4 parts of centipede, 2 parts of green skin, After crushing 5 parts of scorpion, 5 parts of leech, 2 parts of Artemisia indica, 2 parts of Gentiana ferulica, 3 parts of ferulicum and 6 parts of dried blood, add 4 times its weight of 85wt% ethanol to reflux extraction twice, each time for 1 hour, Combining the two extracts, filtering ...

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Abstract

The invention discloses a mammary gland hyperplasia treatment traditional Chinese medicine transdermal patch with an effect of promoting blood circulation to remove meridian obstruction. The mammary gland hyperplasia treatment traditional Chinese medicine transdermal patch comprises an adhesive layer, an energy layer, a magnetization layer, a medicine film layer and a back lining layer. The energylayer is coated by the back lining layer and a gastight film, the back lining layer is positioned on the upper surface of the energy layer, the gastight film is positioned on the lower surface of theenergy layer, a permanent magnet and the medicine film layer are arranged on the inner side of the gastight film, and the permanent magnet is positioned between the gastight film and the medicine film layer; the back lining layer is arranged on the outer side of the adhesive layer; the medicine film layer is made of traditional Chinese medicine components and high polymer materials by means of composition, and the high polymer materials are made of PLA (polylactic acid) and PHB (polyhydroxybutyrate) by means of composition. The mammary gland hyperplasia treatment traditional Chinese medicinetransdermal patch has the advantages that the traditional Chinese medicine components are coated in the high polymer materials which are made of the PLA and the PHB by means of composition, heating substances in the energy layer can be in contact with oxygen to spontaneously produce heat to act on the medicine film layer, accordingly, quick release of the efficacy can be promoted, and excellent effects of relieving and eliminating pain and swelling due to mammary gland hyperplasia can be realized by the mammary gland hyperplasia treatment traditional Chinese medicine transdermal patch; excellent curative effects can be realized for chronic diseases such as cervical spondylosis, lower back pain, chronic strain, spondylalgia, rheumatoid arthritis and osteoarthritis by the mammary gland hyperplasia treatment traditional Chinese medicine transdermal patch.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicine patches, and in particular relates to a traditional Chinese medicine transdermal drug delivery patch for promoting blood circulation and dredging collaterals, which is clinically used for treating mammary gland hyperplasia. Background technique [0002] Mammary gland hyperplasia is a breast disease with one or more tissue hyperplasia of acinar epithelium, ductal epithelium, and fibrous connective tissue as the main pathological change. . The age of onset is concentrated in 20 to 50 years old, and the incidence rate drops sharply after 50 years old. Its incidence rate accounts for about 40% of women of childbearing age, accounts for 75% of all breast diseases, and is the most common breast disease. It is generally believed that insufficient progesterone causes hyperplasia and involution of the mammary glands in the menstrual cycle, and this disease develops over time. [000...

Claims

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Application Information

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IPC IPC(8): A61K36/9068A61K9/70A61K47/34A61P15/14A61P19/08A61P19/02A61P29/00A61N2/08A61M37/00A61F7/03A61K35/62A61K35/646A61K35/648
CPCA61F7/032A61F2007/0261A61K9/0004A61K9/0009A61K9/7069A61K35/62A61K35/646A61K35/648A61K36/185A61K36/23A61K36/233A61K36/28A61K36/286A61K36/288A61K36/324A61K36/328A61K36/515A61K36/708A61K36/714A61K36/736A61K36/74A61K36/752A61K36/889A61K36/896A61K36/898A61K36/902A61K36/9066A61K36/9068A61K2236/333A61K2236/39A61M37/00A61M2037/0007A61N2/002A61N2/008A61N2/06A61P15/14A61P19/02A61P19/08A61P29/00A61K2300/00
Inventor 许汉珍许建儿
Owner 福建鑫美源生物医药工程有限公司
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