High-molecular antibacterial liquid membrane and preparation method thereof

Abstract

The invention relates to a high-molecular antibacterial liquid membrane which comprises, by weight, 100 parts of purified water, 100 parts of ethyl alcohol, 10-30 parts of polyvinyl alcohol, 10-30 parts of chitosan, 1-5 parts of dimethyl phthalate, 1-10 parts of diethyl ether, 1-10 parts of glycerinum and 0.02-0.08 part of nano-silver colloid. According to the liquid membrane, the polyvinyl alcohol and the chitosan are compounded and supply shortcomings each other, the prepared membrane is good in adhesiveness and rapidly formed and has good biocompatibility and breathability and remarkable antibacterial and anti-inflammation function supplemented by nano-silver, wound healing is facilitated, the chitosan is low in cost, and the liquid membrane is economical and practical.

Description

technical field [0001] The invention relates to the technical field of membrane materials, and more particularly, to a polymer antibacterial liquid membrane and a preparation method thereof. Background technique [0002] For daily small wounds, solid medical adhesive tapes, such as band-aids, are most commonly used. However, band-aids also have many disadvantages, such as poor protection for irregular wounds, and lack of water resistance, which causes external pollutants to damage the wound. Infection, airtightness leads to contamination of wounds by secretions such as oil and so on. [0003] With the development of film material technology, film-forming materials have begun to be used in the field of medicine. The film-forming material is mixed with functional drugs and volatile solvents to form a liquid film, which is coated on the wound and the solvent volatilizes at room temperature to form a liquid film. The layer of film covers the wound, has good ductility and waterp...

AI Technical Summary

Problems solved by technology

[0004] Polymers are commonly used film-forming materials. Polymer film-forming materials with good biocompatibility include polyvinyl alcohol, nitrocellulose materials, chitosan materials and cyanoacrylates. Polyvinyl alcohol film-forming adhesion Good, but the film-forming speed is slow and there is a problem of poor air permeability. Nitrocellulose film-forming is fast and is a better film-forming material, but the cost is high. Chitosan is a natural polymer and is biocompatible. Good performance, fast film formation, good air permeability, biodegradability, hemostatic activity, anti-infection and acceleration of wound healing, but chitosan has weak adhesion, easy to fall off, antibacterial activity is not very strong, cyano Acrylic materials have problems such as fast reaction speed, poor water resistance, and high brittleness. Their properties can be improved through modification, but the modification process is complicated and increases the cost.

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