Formula of composition for treating and preventing diabetes and complications of diabetes and preparation method thereof
A composition and diabetes technology, applied in the field of health food and medicine, can solve the problems of insufficient inhibition, limited curative effect, improper peripheral clearance of glucose, etc., and achieve the effect of inhibiting blood sugar rise, controlling blood sugar level, and reducing blood sugar fluctuation
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Embodiment 1
[0017] The preparation method of embodiment 1 mulberry leaf extract
[0018] Known according to the prior art, the main active substances in mulberry leaves for treating diabetes are alkaloids, polysaccharides and flavonoid glycosides. These kinds of active substances have good water solubility, so extraction with water as a solvent can not only effectively extract the active ingredients, but also be safe and cost-effective during production and use.
[0019] The determination method of alkaloids is not very mature, the error is relatively large, the activity of brass compounds is lower than that of alkaloids and polysaccharides, and polysaccharides not only have the highest content in the extract, but also are the main active components, and the detection method is relatively simple, so this paper The polysaccharide content is selected as the quality control index of the mulberry leaf extract in the invention, and the polysaccharide content detection method used is the anthro...
Embodiment 3-11
[0044] Example 3-11 Preparation of pharmaceutical composition
[0045] Benfotiamine is dissolved in a small amount of flaxseed oil and then added to whole flaxseed oil at room temperature. According to the material ratio (see the table below), slowly mix the mild oil and α-lipoic acid, and stir for 2 hours until the soluble part dissolves in the oil, then add other raw materials and mix well. Grind through a colloid mill until the hand feels fine, and then use a homogenizer to homogenize until the particles are less than 0.5μm. After completion, pour the material into a vacuum stirring degasser, and vacuum condition to - 0.09mpa. No need to heat, stir and degas for 2-3 hours. Material spare.
[0046] Glue adjustment: add gelatin, glycerin, and deionized water into the rubber mixing tank at a ratio of 1:0.4-0.6:1, heat in a water bath to 60°C-65°C, vacuum -0.05mPa to -0.09mPa, stir for 3-4 hours, and release The gelatin solution is kept in an insulated bucket for 6-8 hours a...
Embodiment 12
[0051] Example 12 Composition formulation for food processing with high sugar content
[0052] The composition formula used in this example is L-arabinose, hawthorn extract and vitamin B1, the recommended daily intake is 3-4% of the sugar content in food for L-arabinose, and 450-550mg for hawthorn extract / day, vitamin B1 is 25-35mg / day, the preferred material ratio is L-arabinose is 3.5% of the sugar content in food, hawthorn extract is 500mg / day, vitamin B1 is 30mg / day. Let's take the production of yogurt as an example, but the formula is not limited to yogurt, and the formula can also be used for foods with high sugar content such as carbonated drinks, fruit juices, ice cream and milk drinks.
[0053] Material ratio:
[0054] material
Proportion / %
material
Proportion / %
Milk Powder Reconstituted Milk
89
Fruit Milk Emulsion Stabilizer
0.4
4
L-arabinose
0.21
fragrance
0.1
Hawthorn Extract
...
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