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Absorbable and degradable hemostatic fiber material

Inactive Publication Date: 2018-11-13
INST OF APPLIED CHEM JIANGXI ACAD OF SCI
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the operation of this patent is cumbersome, and the samples prepared according to this method are severely degraded and fractured, and the strength loss is large, resulting in an unsatisfactory hemostatic effect.

Method used

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  • Absorbable and degradable hemostatic fiber material
  • Absorbable and degradable hemostatic fiber material
  • Absorbable and degradable hemostatic fiber material

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0031] The absorbable and degradable hemostatic fiber material of this embodiment has the following components in parts by weight:

[0032]

[0033] Wherein, the functional fibers are selected from one or more of chitosan fibers, chitosan derivative fibers, chitin fibers, chitin derivative fibers, alginic acid fibers and cellulose derivative fibers.

[0034] Wherein, the hemostatic agent is selected from one or more of collagen, fibrin, hyaluronic acid, alginic acid, porous starch and derivatives thereof.

[0035] Wherein, the water absorbing agent is selected from one or more of polyanionic polysaccharides, starch derivatives, polyacrylic acid and derivatives thereof.

[0036] Wherein, the degradable polymer material is selected from polylactic acid polymer material, polylactide polymer material, polycaprolactone polymer material and polyglycolide polymer material.

[0037] Wherein, the reinforcing agent is one or more of cellulose polymer, pyrrolidone polymer and polypro...

Embodiment 2

[0046] The absorbable and degradable hemostatic fiber material of this embodiment has the following components in parts by weight:

[0047]

[0048] Wherein, the functional fibers are selected from one or more of chitosan fibers, chitosan derivative fibers, chitin fibers, chitin derivative fibers, alginic acid fibers and cellulose derivative fibers.

[0049] Wherein, the hemostatic agent is selected from one or more of collagen, fibrin, hyaluronic acid, alginic acid, porous starch and derivatives thereof.

[0050] Wherein, the water absorbing agent is selected from one or more of polyanionic polysaccharides, starch derivatives, polyacrylic acid and derivatives thereof.

[0051] Wherein, the degradable polymer material is selected from polylactic acid polymer material, polylactide polymer material, polycaprolactone polymer material and polyglycolide polymer material.

[0052] Wherein, the reinforcing agent is one or more of cellulose polymer, pyrrolidone polymer and polypro...

Embodiment 3

[0061] The absorbable and degradable hemostatic fiber material of this embodiment has the following components in parts by weight:

[0062]

[0063] Wherein, the functional fibers are selected from one or more of chitosan fibers, chitosan derivative fibers, chitin fibers, chitin derivative fibers, alginic acid fibers and cellulose derivative fibers.

[0064] Wherein, the hemostatic agent is selected from one or more of collagen, fibrin, hyaluronic acid, alginic acid, porous starch and derivatives thereof.

[0065] Wherein, the water absorbing agent is selected from one or more of polyanionic polysaccharides, starch derivatives, polyacrylic acid and derivatives thereof.

[0066] Wherein, the degradable polymer material is selected from polylactic acid polymer material, polylactide polymer material, polycaprolactone polymer material and polyglycolide polymer material.

[0067] Wherein, the reinforcing agent is one or more of cellulose polymer, pyrrolidone polymer and polypro...

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Abstract

The invention discloses an absorbable and degradable hemostatic fiber material. The absorbable and degradable hemostatic fiber material is prepared from the following components in parts by weight: 80to 90 parts of functional fibers, 3 to 8 parts of degradable high molecular material, 1 to 3 parts of reinforcing agent, 0.5 to 1.5 parts of catalyst, 0.4 to 0.8 part of anti-sticking agent and 0.3 to 0.7 part of plasticizer. The absorbable and degradable hemostatic fiber material prepared by spinning and blending the functional fibers and the degradable high molecular material, and adding the reinforcing agent, the catalyst, the anti-sticking agent and the plasticizer has good biocompatibility, biodegradability and biological absorption performance; the absorbable and degradable hemostatic fiber material is used for stopping bleeding, the hemostatic effect is good and the hemostatic effect is rapid; the hemostatic fiber material disclosed by the invention can be degraded and absorbed andis safer.

Description

technical field [0001] The invention relates to the technical field of implanted medical materials, in particular to an absorbable and degradable hemostatic fiber material. Background technique [0002] Hemostatic materials can generally be divided into non-degradable hemostatic materials and degradable hemostatic materials. Non-degradable hemostatic materials (such as commonly used ordinary gauze and bacterial cellulose dressing) are usually used for surface hemostasis. When a non-degradable hemostatic material is used for hemostasis in vivo, it needs to be removed after use, otherwise it will easily cause severe foreign body sensation if it is in contact with the wound for a long time. The degradable hemostatic material can be absorbed and degraded by the human body. [0003] After searching the prior art, Chinese invention patent application 201410848483.0 (publication date: May 6, 2015) discloses a preparation process of regenerated cellulose fiber absorbable hemostati...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61L24/10A61L24/08A61L24/06A61L24/04A61L24/00
CPCA61L24/001A61L24/0015A61L24/0021A61L24/0042A61L24/046A61L24/06A61L24/08A61L24/102A61L24/106A61L2300/412A61L2300/418A61L2400/04C08L5/08C08L5/04C08L1/02C08L3/02C08L5/00C08L33/02C08L67/04C08L39/06C08L23/12C08L29/04C08L71/02
Inventor 张鹏舒泉水孙复钱董晓娜
Owner INST OF APPLIED CHEM JIANGXI ACAD OF SCI
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