Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Preparation method and application of selaginella tamariscina extract

A technology of resurrection grass and extract, applied in skin care preparations, medical preparations containing active ingredients, drug combinations, etc. Extraction and separation application reports and other issues, to achieve significant free radical scavenging, less demanding, less damage effect

Inactive Publication Date: 2019-03-01
广州诗美化妆品有限公司
View PDF4 Cites 4 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, the research on the active ingredients in Resurrection Grass mainly focuses on flavonoids and alkaloid compounds. There are no reports on the extraction, separation and application of total polyphenols in Resurrection Grass, and there are no reports on anti-aging aspects of total polyphenols in Resurrection Grass.

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Preparation method and application of selaginella tamariscina extract
  • Preparation method and application of selaginella tamariscina extract
  • Preparation method and application of selaginella tamariscina extract

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0076] Grind 100g of resurrection herb into 40 mesh powder, add 3kg of 50% (W / W) ethanol solution, stir and extract at 60°C for 120 minutes, centrifuge to remove the medicinal residue, concentrate the centrifugate to 200g, then add 10% (w / w) concentration of Ca(OH) 2 Adjust the pH value of the solution to 12.0, let it stand overnight, centrifuge, collect the precipitate, add 150g of pure water to the precipitate, stir and dissolve at 60°C, add 10% (w / w) hydrochloric acid solution, adjust the pH value to 4.0, and add hexamethasone for activation ( Dry at 105°C under normal pressure for 2 hours) of 5g of granular activated carbon (Jiangsu Chengsen Charcoal Technology Co., Ltd. 202 shell granular activated carbon), stir at room temperature for 30 minutes and filter to remove the activated carbon, which is the resurrection grass extract. The measured relative density was 1.045 (25°C).

Embodiment 2

[0078] Grind 5 kg of resurrection herb into 70-mesh powder, add 100 kg of 70% (W / W) 1,3-butanediol solution, stir and extract at 80°C for 60 minutes, centrifuge to remove medicinal residues, and concentrate the centrifugate After reaching 15kg, add 10% (w / w) concentration of Fe(OH) 3 Adjust the pH value of the solution to 11.5, let it stand for 5 hours, centrifuge, collect the precipitate, add 5kg of pure water to the precipitate, stir and dissolve at 80°C, add 5% (w / w) hydrochloric acid solution, adjust the pH value to 4.5, add ethyl alcohol to clean (The processing method is operated according to the operating instructions of the resin) 500g D309 decolorizing resin (Shanghai Zhengguang Resin Factory), after stirring at room temperature for 30 minutes, filter and remove the resin, which is the resurrection grass extract, and the relative density measured at this time is 1.068 (25° C.) .

Embodiment 3

[0080] Grind 1kg of resurrection herb into 100 mesh powder, add 100kg of propylene glycol, extract at 70°C for 120 minutes, centrifuge to remove the medicinal residues, concentrate the centrifugate to 0.5kg, then add 10% (w / w) concentration of Mg ( Oh) 2 Adjust the pH value of the solution to 10.6, let it stand for 24 hours, centrifuge, collect the precipitate, add 5kg of pure water to the precipitate, stir and dissolve at 70°C, add 10% (w / w) acetic acid solution, adjust the pH value to 5.0, and add hexane for activation (dried at 105°C under normal pressure for 2 hours) with 300g of activated carbon (Jiangsu Chengsen Charcoal Technology Co., Ltd., powdered carbon), 70°C for 60 minutes after stirring at 70°C to remove the activated carbon by filtration, which is the extract of Resurrection Grass, at this time The measured relative density was 1.023 (25°C).

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

PropertyMeasurementUnit
Relative densityaaaaaaaaaa
Relative densityaaaaaaaaaa
Login to View More

Abstract

The invention discloses a preparation method and application of a selaginella tamariscina extract. The method comprises the following steps that 1, a solvent is added into smashed selaginella tamariscina, extraction is conducted at the temperature of 0-80 DEG C, herb residues are removed through centrifugation, and a centrifugate is obtained; the centrifugate is concentrated, the pH value of the centrifugate is adjusted to be alkaline, standing and centrifugation are conducted, and sediment is collected and obtained; 2, after the sediment is dissolved by adding water, the pH value is adjustedto be acidic, decoloration is conducted to obtain the selaginella tamariscina extract. The method is simple in operation, the extracting efficiency is high, the content of total polyphenol in the obtained selaginella tamariscina extract is high, and at the relative density of 1.010-1.090, the content of the total polyphenol in the obtained selaginella tamariscina extract is higher than or equal to50 mg / mL. The selaginella tamariscina extract is high in safety performance and has the advantages that free radicals are remarkably removed, oxidation is resistant, and proliferation of human embryonic kidney cells is promoted; the extract is a liquid product, so that the extract is conveniently added into cosmetics and suitable for industrialized application and popularization.

Description

technical field [0001] The invention belongs to the technical field of plant extraction and chemical engineering, and in particular relates to a preparation method and application of an extract of resurrection grass. Background technique [0002] The scientific name of the resurrection grass is Selaginella, and it is also called the resurrection grass because of its extreme drought resistance and the characteristics of "death" and resurrection. It is mainly distributed in China, Siberia in Russia, the Korean Peninsula, Japan, India and the Philippines, etc. It is mostly born on sunny hillside rocks, or in arid deserts and rock crevices. It is both ornamental and medicinal, and the whole plant has the effects of hemostasis and astringency. Existing studies have shown that the resurrection grass extract can enhance cell vitality and metabolism, activate regenerative skin cells, enhance the antioxidant capacity of skin cells, reduce skin redness, fight rashes, accelerate woun...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): A61K8/9741A61Q19/08A61K36/11A61P39/06
CPCA61K36/11A61K2236/33A61K2236/331A61K2236/333A61K2236/53A61Q19/08A61K8/9741A61P39/06
Inventor 刘明富
Owner 广州诗美化妆品有限公司
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com