Marine fish free peptide extract, and preparation method and applications thereof

An extract and marine fish technology, applied in the field of marine fish free peptide extract and preparation thereof, can solve the problems of troublesome cooking process, unsatisfactory curative effect, complicated preparation process, etc., and achieve optimal removal of skin chloasma, Optimize the effect of repairing fine lines and improving skin nutrition

Inactive Publication Date: 2019-03-08
GUANGDONG SHINYEE MARINE BIOLOGY ENG CORP +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] At present, external application of anti-oxidant polyphenols, saponins and other bioactive ingredients are mostly used in the clinical treatment of chloasma. The cure rate is low, the recurrence rate is high, the curative effect is not obvious, and the medication is inconvenient.
However, the freckle-removing and whitening health care products sold on the market have complex preparation processes, and most of them are traditional Chinese medicine ingredients. The cooking process is troublesome, the taste is not good, and the curative effect is not very satisfactory

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0032] In this embodiment, a method for preparing a marine fish free peptide extract, the steps are as follows:

[0033] (1) Use flat rudder skipjack as raw material, after pre-treatment (removing head, viscera, gills, scales, etc.), the meat grinder is minced;

[0034] (2) Mix the ground rudder skipjack with water at a mass ratio of 1:2. ): 550*330*360, ultrasonic power: 500W) to extract for 20 minutes, then centrifuge with a three-legged centrifuge (built-in 600-mesh cloth bag) to remove the residue, and collect the first extract; :2 mix well, under room temperature (25 ℃) condition, ultrasonic (ultrasonic frequency: 20kHz, ultrasonic frame size (L×W×Hmm): 550*330*360, ultrasonic power: 500W) extract 20 minutes, then use The three-legged centrifuge (built-in 600-mesh cloth bag) performs the second centrifugation to remove the residue and collect the second extract;

[0035] (3) The first extract and the second extract are combined, vacuum concentrated and spray-dried to ob...

Embodiment 2

[0037] In this embodiment, a health product with the effect of improving chloasma, the raw material components are as follows in parts by weight:

[0038] 70 parts of the bonito free peptide extract of Example 1, 29 parts of acerola powder, and 1 part of sucralose.

[0039] The preparation method of the health product is as follows: fully mix the bonito free peptide extract, acerola cherry powder, and sucralose, and the product is packed in an aluminum platinum bag, 5.0 g / bag.

[0040] Efficacy experiment: 20 patients with chloasma were divided into experimental group 1 and experimental group 2, with 10 people in each group. Experimental group 1 only took the bonito free peptide extract of embodiment 1, and experimental group 2 took embodiment 2 health care products. The method of administration is as follows: 5.0g per day, filled with warm water at 80°C, and taken orally. One month later, 5 people in the experimental group 1 said it was effective, and 8 people in the experi...

Embodiment 3

[0042] In this embodiment, a method for preparing a marine fish free peptide extract, the steps are as follows:

[0043] (1) Yellowfin tuna is used as raw material, after pre-treatment (removing the head, viscera, gills, scales, etc.), the meat grinder is minced;

[0044] (2) Mix the minced yellowfin tuna with water at a mass ratio of 1:2, and at room temperature (25°C), ultrasonically (ultrasonic frequency: 20kHz, sonicator frame size (L×W×H mm) : 550*330*360, ultrasonic power: 500W) to extract for 30 minutes, then use a three-legged centrifuge (built-in 600-mesh cloth bag) to centrifuge to remove the residue, and collect the first extraction; then the residue and water are in a mass ratio of 1: 2 Mix well, and extract with ultrasound (ultrasonic frequency: 20kHz, ultrasonic frame size (L×W×Hmm): 550*330*360, ultrasonic power: 500W) for 15 minutes at room temperature (25°C), and then use three Foot centrifuge (built-in 600-mesh cloth bag) for the second centrifugation to rem...

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PUM

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Abstract

The invention relates to a marine fish free peptide extract, and a preparation method and applications thereof. The preparation method comprises the following steps: (1) mincing pretreated marine fishes; and (2) adding water into the minced marine fish in the step (1), performing ultrasonic extraction at least once, collecting the extracting solution, and performing concentration and drying. The condition for the ultrasonic extraction is as follows: ultrasonic frequency is 10-20 kHz, ultrasonic power is 400-600W, and ultrasonic time is 15-30min. The marine fish free peptide extract prepared bythe preparation method has a high content of histidine dipeptide, glutathione and taurine, and can effectively improve chloasma, and the preparation method is simple and efficient.

Description

technical field [0001] The invention relates to the technical field of health food, in particular to marine fish free peptide extract and its preparation method and application. Background technique [0002] Marine fish resources are abundant, and the crude extract of free peptides from marine fish is not only delicious, but also has high nutritional value, fast absorption and utilization, and high safety. [0003] Due to the acceleration of the pace of modern life, the deteriorating living environment, and the long-term use of computers by white-collar workers, more and more people, especially women, have chloasma and small cracks on their skin. Chloasma is a skin disease with brown or black pigmentation on the face caused by increased melanin in the skin. It is one of the intractable diseases in dermatology. Melanin is tyrosine under the action of tyrosinase to generate dopa from colorless tyrosine, and dopa becomes dopaquinone under the action of tyrosinase, and then und...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A23L33/18A23L33/175A23L33/10
CPCA23L33/10A23L33/175A23L33/18A23V2002/00A23V2200/318A23V2250/0644A23V2250/55
Inventor 刘扬王炎冰潘建文龙秀红
Owner GUANGDONG SHINYEE MARINE BIOLOGY ENG CORP
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