Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Povidone iodine compound, preparation method and application thereof

A technology of povidone-iodine and a composition, which is applied in the field of oral care, can solve the problems of pungent taste of mouthwash, aggravate carcinogenicity, serious tooth decay, etc., and achieve excellent hemostatic effect, less irritation, and the effect of relieving bleeding gums

Active Publication Date: 2019-03-26
SHANGHAI YUKING WATER SOLUBLE MATERIAL TECH
View PDF7 Cites 1 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, in addition to aggravating dry mouth, alcohol may in turn lead to bad breath and severe tooth decay. The addition of high levels of alcohol will also make the mouthwash taste more spicy. Its greater potential danger is that it may aggravate the risk of cancer. The main reason is that such products need to stay in the mouth for a period of time during use. In the environment of the mouth, ethanol may be oxidized to acetaldehyde under the action of certain enzymes. Mouthwash products enter the market
[0006] For this reason, it is particularly important to develop a mouthwash product that can efficiently kill oral pathogenic bacteria, overcome the unsafe factors of ethanol in large quantities, and have a refreshing mouthfeel

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Povidone iodine compound, preparation method and application thereof
  • Povidone iodine compound, preparation method and application thereof
  • Povidone iodine compound, preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

preparation example 1

[0077] Preparation example 1, prepare povidone-iodine powder

[0078] The preparation method of povidone iodine powder comprises the steps:

[0079] (1) Add the PVP homopolymer YK006S30 / 60, solid iodine and solid salicylic acid into the vacuum reaction kettle with grooved anchor grid stirring paddle in sequence, then seal the lid of the reaction kettle and control the temperature at 25°C , control the stirring speed at 150r / min, stir and mix for 150min, then increase the temperature by 5°C every 90min, and increase the speed by 25r / min at the same time, until the reaction temperature rises to 90°C, continue the heat preservation reaction for 480min, and obtain the intermediate material; among them, PVP homopolymer The mass ratio of substance and solid iodine is 5.4:1, and the addition amount of solid salicylic acid is 0.01% of the total mass of PVP homopolymer and solid iodine;

[0080] (2), the intermediate material that step (1) is obtained is crossed 80 mesh sieves, adopts...

preparation example 2

[0082] Preparation example 2, prepare povidone-iodine powder

[0083] The preparation method of povidone iodine powder comprises the steps:

[0084] (1), PVP homopolymer Kolidone, solid iodine and anhydrous citric acid are added into the vacuum reactor with grooved anchor grid type stirring paddles in sequence, and then the lid of the reactor is sealed, and the temperature is controlled to be 30°C. The stirring speed is 100r / min, stirring and mixing for 300min, and then the temperature is raised by 3°C every 100min, and the speed is increased by 50r / min at the same time, until the reaction temperature rises to 100°C, and the heat preservation reaction is continued for 240min to obtain the intermediate material; among them, PVP homopolymer, The mass ratio of solid iodine is 4.4:1, and the amount of anhydrous citric acid added is 0.05% of the total mass of the PVP homopolymer and solid iodine;

[0085] (2), the intermediate material that step (1) is obtained is crossed 80 mesh ...

preparation example 3

[0087] Preparation example 3, prepare povidone-iodine powder

[0088] The preparation method of povidone iodine powder comprises the steps:

[0089] (1), the PVP homopolymer Plasdone K-25 of formula quantity, solid iodine and solid sodium salicylate are added successively in the vacuum reactor with grooved anchor grid formula stirring paddle, then seal reactor lid, control temperature is 20°C, control the stirring speed to 300r / min, stir and mix for 300min, then increase the temperature by 10°C every 80min, and increase the speed by 75r / min at the same time, until the reaction temperature rises to 80°C, continue the heat preservation reaction for 720min, and obtain the intermediate material; among them, PVP The mass ratio of homopolymer to solid iodine is 6.4:1, and the amount of solid sodium salicylate added is 0.1% of the total mass of the PVP homopolymer and solid iodine;

[0090] (2), the intermediate material that step (1) is obtained is crossed 80 mesh sieves, adopts pu...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention provides a povidone iodine compound which comprises the following components in parts by weight: 10-25 parts of povidone iodine powder, 1-10 parts of polyoxyethyl nonyl phenyl ether, 50-100 parts of polyhydric alcohols, 0.1-0.5 part of zinc oxide, 0.1-2.1 parts of flavoring agent, 0.1-1 part of acetoglycine ethylenediamine and 0.4-1.8 parts of ethyl p-aminobenzoate, wherein the flavoring agent includes one or two of storax oil and star anise oil. An oral care product prepared from the povidone iodine compound provided by the invention has excellent anti-microbial, pain-relievingand bleeding-stopping effects, little irritation to oral mucosa and functions of preventing and treating oral diseases.

Description

technical field [0001] The invention belongs to the field of oral care, and relates to a povidone-iodine composition and a preparation method thereof. Background technique [0002] Oral diseases are common frequently-occurring diseases caused by various pathogenic bacteria in the oral cavity, which directly affect people's health. Oral care is therefore one of the most important aspects of personal hygiene. People usually use toothbrush and oral care products (such as toothpaste or tooth powder) to clean teeth and oral cavity. Brushing at least twice a day ensures good oral hygiene and prevents oral disease by minimizing the accumulation of oral bacteria that accumulate in the mouth at night while sleeping or during the day when people eat and drink. However, due to the short residence time of the oral care products in the oral cavity, the antibacterial effect of the existing oral care products is not obvious, and bacteria still act on the oral mucosa within about 12 hours...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): A61K8/20A61K8/27A61K8/34A61K8/44A61K8/81A61K8/86A61K8/92A61P1/02A61P7/04A61P31/04A61Q11/00
CPCA61K8/20A61K8/27A61K8/345A61K8/44A61K8/8176A61K8/86A61K8/922A61Q11/00A61P1/02A61P7/04A61P31/04
Inventor 王宇熊俊超陈占魏亚娜
Owner SHANGHAI YUKING WATER SOLUBLE MATERIAL TECH
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com