A kind of tea tree essential oil enteric coating pellet and its preparation method and application

A technology of tea tree essential oil and enteric coating, which is applied in the application, the molding or processing of animal feed, animal husbandry and other directions, can solve the problems of instability of tea tree essential oil, achieve good feeding effect, prevent animal diseases, and improve feed conversion. The effect of efficiency

Active Publication Date: 2020-04-10
天津中澳嘉喜诺生物科技有限公司
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] The purpose of the present invention is to provide a tea tree essential oil enteric-coated pellet and its preparation method and application. The tea tree essential oil enteric-coated pellet provided by the invention can effectively solve the problem of tea tree essential oil being unstable, volatile, and the smell of special essential oil affecting animal collection. Improve the palatability of farmed animals, reduce the stimulating effect of tea tree essential oil on the digestive system of animals, increase animal feed intake, improve animal health, and thus improve production performance

Method used

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  • A kind of tea tree essential oil enteric coating pellet and its preparation method and application
  • A kind of tea tree essential oil enteric coating pellet and its preparation method and application
  • A kind of tea tree essential oil enteric coating pellet and its preparation method and application

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preparation example Construction

[0044] The raw materials for preparing the pellet core include cellulose, excipients and water;

[0045] The raw materials for the preparation of the coating solution include: methacrylic acid-ethyl acrylate copolymer, inorganic filler, anti-photolysis material, coating material, plasticizer and water.

[0046] In the present invention, unless otherwise specified, all raw material components are commercially available products well known to those skilled in the art.

[0047]In the present invention, in parts by weight, the raw materials for preparing the enteric-coated pellets of tea tree essential oil include 40 to 50 parts of pellet cores, preferably 41 to 48 parts, more preferably 41 to 45 parts, and most preferably 41 parts. ~43 servings. In the present invention, the diameter of the core pellets is preferably 0.8-1.0 mm, more preferably 0.8 mm. In the present invention, the raw materials for preparing the pellet core include cellulose, excipients and water. In the pres...

Embodiment 1

[0066] Fully mix 5.6kg of microcrystalline cellulose, 1.9kg of pregelatinized starch and 4.5kg of pure water, extrude the obtained soft material with an extruder to obtain thin strips with a length of 10cm and a diameter of 0.8mm, and then add the obtained thin strips to Make a ball core with a diameter of 0.8mm in the spheronizer;

[0067] Heat 5.7kg polyethylene glycol 12000 to a molten state, add 2.0kg tea tree essential oil and stir to obtain a tea tree essential oil-polyethylene glycol mixture;

[0068] The ball core and the tea tree essential oil-polyethylene glycol mixture are stirred and condensed, so that the tea tree essential oil-polyethylene glycol mixture is evenly wrapped on the ball core, and the fine powder is removed through a 50-mesh sieve to obtain a drug-loaded ball core;

[0069] 35g sodium carboxymethylcellulose, 80g polyethylene glycol 6000, 50g triethyl citrate, 830g talcum powder, 500g titanium dioxide, 1.67kg methacrylic acid-ethyl acrylate copolymer ...

Embodiment 2

[0072] 3.8kg of microcrystalline cellulose, 0.13kg of pregelatinized starch and 3kg of pure water are fully mixed, and the gained soft material is extruded with an extruder to obtain thin strips with a length of 10 cm and a diameter of 0.8 mm, and then the gained thin strips are added to The ball core with a diameter of 0.8mm is made in a spheronizer;

[0073] Heat 3.8kg of polyethylene glycol 12000 to a molten state, add 1.8kg of tea tree essential oil and stir to obtain a tea tree essential oil-polyethylene glycol mixture;

[0074] The ball core and the tea tree essential oil-polyethylene glycol mixture are stirred and condensed, so that the tea tree essential oil-polyethylene glycol mixture is evenly wrapped on the ball core, and the fine powder is removed through a 50-mesh sieve to obtain a drug-loaded ball core;

[0075] 25g sodium carboxymethylcellulose, 55g polyethylene glycol 6000, 35g triethyl citrate, 600g talcum powder, 350g titanium dioxide, 1.15kg methacrylic acid...

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Abstract

The invention provides a tea tree essential oil enteric coating pellet as well as a preparation method and application thereof, and belongs to the technical field of animal husbandry feeds. The tea tree essential oil enteric coating pellet is prepared from the following components in parts by weight: 40-50 parts of a pellet core, 25-35 parts of a tea tree essential oil-auxiliary material mixture and 25-35 parts of a coating solution. Raw materials for preparing the pill core comprise cellulose, an excipient and water. The coating liquid is prepared from the following raw materials: a methacrylic acid-ethyl acrylate copolymer, inorganic filler, a photolysis resistant material, a coating material, a plasticizer and water. The product can effectively solve the problem that tea tree essentialoil volatilizes easily and special essential oil smell affects animal food intake, effectively reduce the incidence rate of diarrhea and other diseases, remarkably increase the animal food intake, improve the feed conversion efficiency, and is high in safety and free of drug resistance. The product can be added into feed to replace the use of growth-promoting antibiotics in feed additives.

Description

technical field [0001] The invention relates to the technical field of livestock feed, in particular to a tea tree essential oil enteric-coated pellet and a preparation method and application thereof. Background technique [0002] In recent years, the problem of bacterial drug resistance has attracted widespread attention from all over the world. The irrational application or even abuse of antibiotics is one of the important factors causing bacterial drug resistance. Among them, the problem of antibiotic abuse in animal husbandry is particularly serious. threaten human health. [0003] Plant essential oils are secondary metabolites in plants. Among them, the antibacterial activity of Australian tea tree essential oil has been widely recognized by the field of medicine, production practice and researchers. To prevent animal diseases, its good antibacterial activity can even reduce or be widely used in the field of animal farming as an alternative to antibiotics. [0004] At...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): B01J2/02B01J2/20A23K20/10A23K20/105A23K20/158A23K20/20A23K40/30
CPCA23K20/10A23K20/105A23K20/158A23K20/20A23K40/30B01J2/02B01J2/20
Inventor 孟杰民胡少青范惠章马吉飞王子波
Owner 天津中澳嘉喜诺生物科技有限公司
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