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Traditional Chinese medicine composition for treating hypertension-concurrent left ventricular hypertrophy and preparation method thereof

A technology of hypertension and composition, which is applied in the field of traditional Chinese medicine composition, can solve the problems of traditional Chinese medicine composition with many raw materials, cumbersome preparation process, and inaccurate curative effect, so as to prevent the deterioration of heart function, use less medication, and delay myocardial hypertrophy. Effect

Active Publication Date: 2019-10-01
XIANGYA HOSPITAL CENT SOUTH UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] Western medicine is effective in treating hypertensive left ventricular hypertrophy, but long-term use of its side effects has become a major obstacle to life-long medication, which limits the application of western medicine to a certain extent; However, there are technical problems such as many raw materials of traditional Chinese medicine composition, cumbersome preparation process, slow effect, inaccurate curative effect, etc., and there are not many that can be used clinically, especially for the study of traditional Chinese medicine for left ventricular hypertrophy in patients with middle and late stages of hypertension. currently blank
In addition, for patients with early and mid-stage hypertension, Chinese medicine is actually not as effective as Western medicine in terms of simple blood pressure reduction. It is not as fast-acting and easy to take as Western medicine.

Method used

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  • Traditional Chinese medicine composition for treating hypertension-concurrent left ventricular hypertrophy and preparation method thereof
  • Traditional Chinese medicine composition for treating hypertension-concurrent left ventricular hypertrophy and preparation method thereof
  • Traditional Chinese medicine composition for treating hypertension-concurrent left ventricular hypertrophy and preparation method thereof

Examples

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Effect test

Embodiment 1

[0032] Recipe: 15 parts of Salvia miltiorrhiza, 10 parts of sumac, 10 parts of pinellia, 10 parts of tangerine peel, 9 parts of poria cocos, 5 parts of roasted licorice

[0033] Preparation method: Weigh the medicinal materials according to the prescription amount, grind the medicinal materials into coarse powder, and set aside; put a ball of cotton at the bottom of the percolation cylinder, and then spread gauze, add the coarse powder of medicinal materials into the percolation cylinder, add appropriate amount each time, evenly After compaction, continue to install. After loading, compact the medicinal materials, cover with gauze, and fix the percolation cylinder; slowly add 65% ethanol extraction solvent into the percolation cylinder, the amount added is 1 times the volume of the medicinal materials, and seal the cylinder mouth , soak for 1d; open the percolation valve, the percolation rate is 4mL / s, start percolation, replenish ethanol extraction solvent in time during the p...

Embodiment 2

[0035] Recipe: 10 parts of Salvia miltiorrhiza, 15 parts of sumac, 15 parts of pinellia, 15 parts of tangerine peel, 7 parts of poria cocos, 10 parts of roasted licorice

[0036]Preparation method: Weigh the medicinal materials according to the prescription amount, grind the medicinal materials into coarse powder, and set aside; put a ball of cotton at the bottom of the percolation cylinder, and then spread gauze, add the coarse powder of medicinal materials into the percolation cylinder, add appropriate amount each time, evenly After compaction, continue to install. After loading, compact the medicinal materials, cover with gauze, and fix the percolation cylinder; slowly add 65% ethanol extraction solvent into the percolation cylinder, the amount added is 1 times the volume of the medicinal materials, and seal the cylinder mouth , soak for 1d; open the percolation valve, the percolation rate is 4mL / s, start percolation, replenish ethanol extraction solvent in time during the p...

Embodiment 3

[0038] Recipe: 18 parts of Danshen, 7 parts of Sumu, 5 parts of Pinellia, 5 parts of Chenpi, 12 parts of Poria, 3 parts of Zhigancao

[0039] Preparation method: Weigh the medicinal materials according to the prescription amount, grind the medicinal materials into coarse powder, and set aside; put a ball of cotton at the bottom of the percolation cylinder, and then spread gauze, add the coarse powder of medicinal materials into the percolation cylinder, add appropriate amount each time, evenly After compaction, continue to install. After loading, compact the medicinal materials, cover with gauze, and fix the percolation cylinder; slowly add 65% ethanol extraction solvent into the percolation cylinder, the amount added is 1 times the volume of the medicinal materials, and seal the cylinder mouth , soak for 1d; open the percolation valve, the percolation rate is 4mL / s, start percolation, replenish ethanol extraction solvent in time during the percolation process, collect the liqu...

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Abstract

The invention discloses a traditional Chinese medicine composition for treating hypertension-concurrent left ventricular hypertrophy and a preparation method thereof. The traditional Chinese medicinecomposition is prepared from, by weight, 8-20 parts of the roots of red-rooted salvia, 5-20 parts of sappanwood, 5-20 parts of pinellia ternate, 5-20 parts of pericarpium citri reticulatae, 5-20 partsof poria cocos and 3-10 parts of honey-fried licorice roots. The traditional Chinese medicine composition has the functions of promoting blood circulation, removing blood stasis, drying dampness andclearing phlegm, the compatibility is reasonable, cooperative interaction is achieved, the curative effect can be improved, and thus the traditional Chinese medicine composition can treat middle-latestage hypertension left ventricular hypertrophy symptoms which include vertigo, head feeling heavy with a vise or headache with a stab, fixed pain, chest tightness and breath shortness, palpitation and insomnia, abdominal distension, tastelessness and little appetite, emesis and salivation, a dark tongue, white and greasy moss, wiry and rolling pulses or astringent pulses and the like. The traditional Chinese medicine composition has the advantages of safety, reliability, no dependence, remarkable clinical effects and stable and controllable quality. The traditional Chinese medicine composition is extracted by adopting percolation, and can be made into capsules, pills and ointment.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicine compositions, and relates to a traditional Chinese medicine composition for treating hypertension complicated with left ventricular hypertrophy and a preparation method thereof. Background technique [0002] Hypertension is a major chronic disease that affects human health and has become the main cause of stroke, coronary heart disease, and heart and kidney failure. Its "three highs" (high morbidity, high mortality, and high disability) have given Patients, their families, and the public health system pose serious challenges. Therefore, further strengthening research on the prevention and treatment of hypertension has become a major scientific issue in the field of population and health in my country. [0003] Ventricular remodeling is currently considered to be one of the important types of early target organ damage in hypertensive patients. Related studies have shown that 2...

Claims

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Application Information

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IPC IPC(8): A61K36/8888A61P9/12A61P9/06A61P9/00
CPCA61K36/076A61K36/48A61K36/484A61K36/537A61K36/752A61K36/8888A61P9/00A61P9/06A61P9/12A61K2300/00
Inventor 姚佳梅钟广伟邱新建明广峰于平平陈琼
Owner XIANGYA HOSPITAL CENT SOUTH UNIV
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