Unlock instant, AI-driven research and patent intelligence for your innovation.

A kind of dendrobium polysaccharide nanocellulose hydrogel

A technology of nanocellulose and dendrobium polysaccharides, which is applied in the field of hydrogel materials and skin care products, can solve the problems of restricting the promotion and application of skin care products, the reduction of skin care effects, and poor thermal stability, so as to delay skin aging and tighten skin Good effect on aging and thermal stability

Active Publication Date: 2021-06-25
WENZHOU UNIV
View PDF8 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Dendrobium officinale is known as the "Panda in the Pharmaceutical World" in the international medicinal plant world, and is called "Life-saving Immortal Grass" by the folks. It has been proved by modern scientific research that it contains many nutrients such as Dendrobium, flavonoids, amino acids, etc., and among them The highest content is Dendrobium polysaccharide; therefore, there are many skin care products related to Dendrobium officinale in the market, but at present these skin care products have poor thermal stability. The effect is significantly reduced, and the actual needs of the people can no longer be met, thus limiting the promotion and application of these skin care products

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0046] Prepare modified nanocellulose, comprising the following steps:

[0047] Step 1: Put 8 g of cellulose and 2 g of carboxymethyl cellulose into 40 ml of a mixed solvent and stir and mix them for 20 min at a speed of 300 r / min at a temperature of 20° C. to form the first mixed solution; (wherein the mixed solvent It is a mixture of acetone and N,N-dimethylacetamide, the volume ratio is 2:1)

[0048] Step 2: Add 1g modifier to the first mixed solution and stir and mix, and mix for 10 minutes at a speed of 400r / min and a temperature of 20°C to form a second mixed solution; then use 0.01M aqueous sodium hydroxide solution The pH of the second mixed solution was adjusted to 10-11, and at the same time, the temperature of the second mixed solution was raised to 60° C. for modification treatment, and the modification time was 3 hours, thereby preparing modified nanocellulose.

[0049] The modifiers are 3-[2-(pentafluorohexyl)ethoxy]-1,2-cycloethoxypropane, 5-chloro-1-(4-piperid...

Embodiment 2

[0051] The preparation of dendrobium polysaccharide nanocellulose hydrogel comprises the following steps:

[0052] Step 1: Place 2.5g of modified nanocellulose (prepared by Example 1), 0.9g of dendrobium polysaccharide and 0.3g of regulator in 20ml of deionized water, stir and mix, and mix well to form a mixed solution;

[0053] Step 2: Add 0.06g N-hydroxysuccinimide and 0.04g 1-(3-dimethylaminopropyl)-3-ethylcarbodiimide to the mixture, stir and mix for 15 minutes, then add 0.5 g of polyvinyl alcohol and 0.1 g of a crosslinking agent were reacted at a temperature of 70°C for a reaction time of 4 hours to prepare a hydrogel.

[0054] The regulator is 3-mercaptopropionic acid-2-ethyl-2-[(3-mercapto-1-oxopropoxyl)methyl]-1,3-propylene diester, N-bromobutane A mixture of imide and 1,2-epoxy-4-vinylcyclohexane in a mass ratio of 1:2:2.

[0055] The crosslinking agent is a mixture of glutaraldehyde and diglycolic anhydride, and its mass ratio is 4:1.

Embodiment 3

[0057]An essence containing dendrobium polysaccharide nanocellulose hydrogel, the preparation method of which comprises the following steps:

[0058] Step 1: Add 0.4g glycerin, 0.3g propylene glycol, 0.1g sodium hyaluronate, 0.1g mannitol, 0.1g glutathione and 0.1g sodium polyglutamate into 20ml deionized water and stir to mix. Mix at 200rpm and 15°C for 30min to form the third mixed liquid;

[0059] Step 2: Then 3g dendrobium polysaccharide nanocellulose hydrogel (made by embodiment 2), 0.4g xanthan gum, 0.1g pearl powder and 0.2g rose essential oil are added successively in the third mixed solution and stirred and mixed. Mix at 400 rpm and 15°C for 90 minutes to prepare essence lotion.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention discloses a dendrobium polysaccharide nanocellulose hydrogel, which uses modified nanocellulose, dendrobium polysaccharide and polyvinyl alcohol as main raw materials; wherein the dendrobium polysaccharide is obtained from dendrobium candidum, and the modified nanocellulose is a fiber The element is prepared after being treated with a modifier, and the modifier is 3-[2-(pentafluorohexyl)ethoxy]-1,2-cycloethoxypropane, 5-chloro-1-(4-piperidine base)-2-benzimidazole indimidine and the mixture of dimethyl diallyl ammonium chloride; modified nano-cellulose and dendrobium polysaccharide, polyvinyl alcohol have better compatibility; the present invention The obtained hydrogel is a polymer with a high molecular network structure, contains a hydrophilic group and a network structure, can wrap the dendrobium polysaccharide, and has strong stability. The essence dew with dendrobium polysaccharide nanocellulose hydrogel as the main raw material has good biocompatibility, and can delay skin aging at the same time, and has good thermal stability. effects of aging.

Description

technical field [0001] The invention relates to the fields of hydrogel materials and skin care products, and more specifically relates to a dendrobium polysaccharide nanocellulose hydrogel. Background technique [0002] In recent years, with the improvement of people's living standards, people pay more and more attention to skin care, because many chemical synthetic products will not only cause damage to the skin, but also have certain harm to the human body; more and more people prefer natural, Green skin care products, that is, adding various natural extracts to skin care products; the most representative of which is plant polysaccharides. [0003] Dendrobium officinale is known as the "Panda in the Pharmaceutical World" in the international medicinal plant world, and is called "Life-saving Immortal Grass" by the folks. It has been proved by modern scientific research that it contains many nutrients such as Dendrobium, flavonoids, amino acids, etc., and among them The hig...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Patents(China)
IPC IPC(8): C08L1/02C08L1/28C08L5/00C08L29/04C08J3/075C08J3/24
CPCC08J3/075C08J3/246C08J2301/02C08J2401/28C08J2405/00
Inventor 张伟禄邹锦萱陈文健孙襄扬李响齐淑彤劳东豪李雯
Owner WENZHOU UNIV