Skin-repair application made of renewable silicon mineral material and preparation method thereof
A skin repair and mineral technology, applied in the fields of medical science, absorbent pads, bandages, etc., can solve the problems of limited wound tissue healing effect, limited effect at the place of use, poor air permeability, etc., to promote cell migration and shape change. Effect
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Embodiment 1
[0035] Preparation of the gel layer
[0036] S10: Heat the regenerated mineral powder material smaller than 8 microns that has been screened by wind to 120°C, then mix 15 parts of the powder material evenly in silicone, stir for 30 minutes under a magnetic stirrer, and form a white suspension agent;
[0037] S20: At 55°C, add 1 part of carbomer to 80 parts of deionized water to form a stable gel matrix through a gel forming agent composed of triethanolamine and sodium hydroxide. At this time, turn off the temperature controller and continue to maintain homogeneity Stir for 1 hour; then add 0.2 parts of sodium hyaluronate to the gel, wait for the sodium hyaluronate to dissolve, make sure the temperature is greater than 30°C, add 0.1 parts of chitosan, stir well and use citric acid solution to adjust the pH of the gel to 6.2;
[0038] S30: Add the suspension agent obtained in step S10 to the gel obtained in step S20 in batches for mixing, mix evenly after 2 hours, and continue...
Embodiment 2
[0043] Preparation of the gel layer
[0044] S10: Heat the regenerated mineral powder material less than 8 microns that has been screened by wind to 120°C, then mix 18 parts of the powder material evenly in silicone, stir for 30 minutes under a magnetic stirrer, and form a white suspension agent;
[0045] S20: At 55°C, add 2 parts of carbomer to 100 parts of deionized water to form a stable gel matrix through a gel forming agent composed of triethanolamine and sodium hydroxide. At this time, turn off the temperature controller and continue to maintain homogeneity Stir for 1 hour; then add 0.5 parts of sodium hyaluronate to the gel, wait for the sodium hyaluronate to dissolve, make sure the temperature is greater than 30°C, add 0.3 parts of chitosan, stir well and use citric acid solution to adjust the pH of the gel to 6.7;
[0046] S30: Add the suspension agent obtained in step S10 to the gel obtained in step S20 in batches for mixing, mix evenly after 2 hours, and continue ...
Embodiment
[0050] Embodiment technical effect test:
[0051] In order to verify whether the skin repair patch made of the regenerated silicon mineral material of the present invention achieves the expected inventive effect, the cytotoxicity test and the stability test were carried out on the patch prepared by the present invention.
[0052] (1) Stability experiment
[0053] In order to verify the safety performance of this product, a stability experiment has been carried out on this product.
[0054] Experimental method: Store in a 50°C oven for 2 months, 4°C for 2 months, and room temperature for 6 months to test the performance indicators of the regenerated silicon mineral material skin repair patch.
[0055] Table 2 Stability experiments in different environments
[0056]
[0057] It can be seen from Table 2 that after being stored in an oven at 50°C for two months, at 4°C for two months, and at room temperature for six months, the applied product is uniform and delicate, without...
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