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Preparation method and application of polyethylene glycol long-chain alkylamine

A long-chain alkylamine and polyethylene glycol technology, which can be used in applications, skin care preparations, pharmaceutical formulations, etc., can solve the problems of high cost, greasy feeling, etc., and achieve easy operation, low volatilization speed, cheap and easy reagents The effect

Inactive Publication Date: 2020-03-27
名畔科技(镇江)有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, when the above-mentioned moisturizing agents are used, some are too greasy on the senses, and some have higher costs.

Method used

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  • Preparation method and application of polyethylene glycol long-chain alkylamine
  • Preparation method and application of polyethylene glycol long-chain alkylamine

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0024] The two kinds of polyethylene glycol long-chain alkyl amines prepared above, glycerin, butylene glycol, agarose and hydroxyethyl cellulose are formulated into a combined moisturizer at a weight ratio of 1:5:2:2:0.2, and through conversion Two kinds of polyethylene glycol long-chain alkyl amines, two combined moisturizer A and moisturizer B can be obtained; wherein moisturizer A contains polyethylene glycol stearylamine, and moisturizer B contains polyethylene glycol hexadecyl Alkylamine. In addition, remove the polyethylene glycol long-chain alkyl amine, and use glycerin, butylene glycol, agarose and hydroxyethyl cellulose in a weight ratio of 5:2:2:0.2 to form a combined moisturizer C. Take these 3 kinds of moisturizers for a control experiment, select 30 22-52-year-old women with healthy faces and divide them into three groups. After washing the face, use the CK skin tester to test the skin moisture content of the blank area before use. Then, apply moisturizer A in th...

Embodiment 2

[0026] Mix the prepared polyethylene glycol stearylamine with edible alcohol and water at a ratio of 1:1:18 to form preservative A, and mix the prepared polyethylene glycol cetylamine with edible alcohol and water at a ratio of 1:1 :18 is made into preservative B, and the prepared polyethylene glycol cetylamine, edible alcohol, ascorbic acid, and water are made into preservative C according to 5:5:1:89;

[0027] Use preservative A, preservative B, and preservative C respectively for the fresh large yellow croaker caught in the same time, soak for 30 minutes, take out and drain, and store at room temperature (20±5℃). They are the first group and the second group respectively. And the third group, at the same time, the fresh large yellow croaker caught on ice and preserved at the same time was taken as the fourth group. The sensory evaluation of large yellow croaker was carried out on the 20th day of preservation. The evaluation criteria are shown in Table 1, and the evaluation resu...

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PUM

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Abstract

The invention provides a preparation method and an application of polyethylene glycol long-chain alkylamine. Polyethylene glycol long-chain alkylamine is prepared from methoxypolyethylene glycol and long-chain alkylamine as raw materials through ammoniation reaction of silicon dioxide and aluminum oxide. The method is simple and convenient to operate, cheap and easily available in reagent, green,safe, efficient and environment-friendly, and suitable for industrial production. When the polyethylene glycol long-chain alkylamine is used in a skin care product, polyethylene glycol fragments can fully absorb water molecules, and long-chain alkyl fragments have an isolation effect, so that the volatilization speed of moisture is reduced, and a lasting moisturizing function is achieved.

Description

Technical field [0001] The invention relates to the field of organic synthesis and cosmetics, and in particular to a preparation method and application of polyethylene glycol long-chain alkylamine. Background technique [0002] Most skin problems are caused by dehydration of the skin. When the skin is dehydrated, cell metabolism, information transmission, etc. are affected, and even obstacles occur, leading to problems such as dry, rough, tarnished, reduced elasticity, increased or deepened wrinkles, increased pigmentation, and even skin barrier dysfunction. Not only increases the susceptibility of skin diseases, but also induces or aggravates skin diseases such as dry dermatitis, atopic dermatitis, psoriasis, ichthyosis, acne and seborrheic dermatitis. The water content of the stratum corneum of healthy skin should be maintained at 10%-20%. When the water content of the stratum corneum is sufficient, the skin will appear soft, smooth, tender and elastic. Less than 10% of the sk...

Claims

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Application Information

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IPC IPC(8): C08G65/333C08K3/36C08K3/22A61K8/86A61Q19/00A23B4/20
CPCC08G65/33306C08K3/36C08K3/22A61K8/86A61Q19/00A23B4/20C08K2003/2227A23V2002/00A23V2250/082A23V2250/708
Inventor 周丽华
Owner 名畔科技(镇江)有限公司
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