Lipid-lowering pharmaceutical composition, preparation method and application

Abstract

The invention relates to a lipid-lowering pharmaceutical composition, a preparation method and application. The composition is composed of the following medicines: 10 to 30 parts of herba artemisiae scopariae, 10 to 30 parts of radix salviae miltiorrhizae, 10 to 30 parts of raw fructus crataegi, 10 to 30 parts of gynostemma pentaphyllum, 10 to 30 parts of semen cassiae torae and 10 to 30 parts oflotus leaves. The pharmaceutical composition is prepared by water extraction, exerts the medicinal effects of soothing liver and regulating qi, clearing heat and promoting diuresis, promoting blood circulation to remove blood stasis and reducing lipid to reduce weight, is remarkable in clinical use curative effect, has important significance in reducing blood lipid, reducing the risk of cardiovascular diseases of later hyperlipidemia patients and improving the life quality of the patients, and has the advantages of high safety, economy, practicability, convenience in taking and the like.

Description

technical field [0001] The invention relates to the field of medical inventions, in particular to a lipid-lowering pharmaceutical composition, preparation method and application. Background technique [0002] Hyperlipidemia refers to a disease in which one or more lipids of triglyceride, total cholesterol, and low-density lipoprotein in the blood are abnormally increased or high-density lipoprotein is abnormally decreased due to abnormal lipid metabolism in the body. Traditional Chinese medicine believes that the formation of hyperlipidemia is closely related to phlegm and blood stasis. Traditional Chinese medicine believes that the main internal causes of hyperlipidemia are insufficient liver and gallbladder qi, deficiency of heart and spleen, and involvement of the kidneys; overeating fat and sweet, too leisurely and less work, excessive drinking and internal injuries of the seven emotions are the main pathogenic factors of hyperlipidemia, such as "Danxi Heart Method" rec...

AI Technical Summary

Problems solved by technology

This formula has certain lipid-lowering curative effect, but there are following defects in this invention: ① contains rhubarb in the side, and rhubarb has the functions of attacking stagnant stagnation, clearing away hot and humid , purging fire, cooling blood, removing stasis, detoxification, etc. effect , but for those who are physically weak, it is easy to cause diarrhea, fatigue and other adverse symptoms; ②The whole prescription has no medicine for nourishing blood and promoting blood circulation, so it is not suitable for hyperlipidemia caused by phlegm and blood stasis; ③The preparation method does not specify the amount of water and decoction time, effective The extraction rate of ingredients is not easy to grasp

", but this invention has the following defects: 1. contains rhubarb in the side, and rhubarb has the functions of attacking stagnant, clearing hot and humid , purging fire, cooling blood, removing stasis, detoxification, etc. effect

But there are following defects in this invention: 1. contain rhubarb in the side, and rhubarb has the functions of attacking stagnation, clearing hot and humid , purging fire, cooling blood, removing stasis, detoxification, etc. effect ; People who are physically weak are likely to cause diarrhea, fatigue and other adverse symptoms; ②Ginseng is a tonic medicine, and long-term use has the disadvantage of nourishing and obstructing Qi; ③There are many medicinal flavors and high cost; ④This prescription is used for lowering blood lipids , anti-peroxidation damage, significantly improve liver fat metabolism, anti-fatty liver and liver protection and lipid-lowering effects, and the curative effect on hyperlipidemia caused by phlegm and blood stasis has not been recorded; ⑤The cooking time is longer and the cost is higher

[0009] However, this invention has the following defects: 1. 18 kinds of medicines are used, which have more medicinal flavors and higher cost; 2. The preparation method uses ethanol extraction, and the cost is higher than that of water; , promoting blood circulation and reducing fat; ④ This prescription has the effects of lowering blood fat, antibacterial, lowering blood sugar, and anti-oxidation.

But there is following defect in this invention: 1. adopt 14 kinds of medicines, and the taste of medicine is more, and cost is higher; hot and humid , purging fire, cooling blood, removing stasis, detoxification, etc. effect , for those who are physically weak, it is easy to cause diarrhea, fatigue and other adverse symptoms; ③ It is biased towards the treatment of obese fatty liver, and the curative effect on hyperlipidemia caused by phlegm and blood stasis (fatty liver has not yet formed) needs to be further demonstrated

But there are following defects in this invention: 1. 22 kinds of medicines are used, and the taste of medicine is more, and the cost is higher; 2. For the treatment of fatty liver, the curative effect of hyperlipidemia caused by phlegm and blood stasis (fatty liver has not yet formed) needs further demonstration

However, this invention has the following defects: ① the curative effect on hyperlipidemia caused by phlegm and blood stasis needs to be further demonstrated; ② the specific preparation method is not clear, and the curative effect needs to be further verified

But the present invention has the following defects: 1. the focus is on the prevention and treatment of fatty liver, and further demonstration is needed for the curative effect of hyperlipidemia caused by phlegm and blood stasis; higher

But this invention has the following defects: 1. the prescription contains black soybeans and jujubes, and the emphasis is on tonic, which is not suitable for tonifying hyperlipidemia caused by phlegm and blood stasis; 2. alcohol extraction is used, and the cost is relatively high compared to boiling

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