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Composition for repairing skin barrier and preparation method and application of composition

A technology for repairing skin and composition, which is applied in the field of composition for repairing skin barrier and its preparation, can solve the problems of limited water content, poor skin barrier, and slow speed of skin barrier repair, and achieve the goal of maintaining steady state and basic health Effect

Active Publication Date: 2020-06-05
广州一一生物技术有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The composition for regulating skin microecology described in this invention can selectively protect probiotics while inhibiting pathogenic bacteria. The composition for regulating skin microecology described in this invention has a good soothing effect in cosmetics, but the effect of repairing the skin barrier The effect is poor, and the amount of water that can be absorbed by the skin is limited, resulting in a slower repair of the skin barrier and a longer time-consuming

Method used

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  • Composition for repairing skin barrier and preparation method and application of composition
  • Composition for repairing skin barrier and preparation method and application of composition
  • Composition for repairing skin barrier and preparation method and application of composition

Examples

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preparation example 1

[0081] This preparation example prepares a sea fennel callus culture, and the sea fennel callus culture filtrate is prepared by the following method:

[0082] (1) Callus induction culture: sea fennel explants were inoculated into agar medium for callus induction culture, the temperature of the induction culture was 20°C, and the time of the induction culture was 14 days, and the callus was obtained. injured tissue;

[0083] (2) Callus particle suspension culture: inoculate the callus obtained in step (1) into MS medium, and carry out shaking culture in a shaking incubator at a speed of 100 r / min, and the temperature of the shaking culture is 20°C , the time of the shaking culture is 14 days to obtain the proliferation callus;

[0084](3) Expanded culture of callus: inoculate the proliferated callus obtained in step (2) into a sterile cell bag for expanded culture, the temperature of the expanded culture is 25°C, and the time of the expanded culture is 24 days , obtaining the...

preparation example 2

[0087] This preparation example prepares tetrahydromethylpyrimidine carboxylic acid, and described tetrahydromethylpyrimidine carboxylic acid is prepared by the following method:

[0088] (A) Cultivation of desert halophilic bacteria: the desert halophilic bacteria were inoculated in SCDLP liquid medium, and cultivated with a rotating speed of 1000r / min in a shaking incubator, and the temperature of the cultivation was 20°C. The time is 48h, and the desert halophilic bacteria cell is obtained;

[0089] (B) Osmotic pressure shock: the desert halophilic bacteria bacterium that step (A) obtains is resuspended in hyperosmotic pressure solution (the hyperosmotic pressure solution comprises: 18% sucrose, 0.1% EDTA, remaining Soak in water) for 1 hour, filter to obtain the precipitated desert halophilic bacterial cell;

[0090] (C) Electrodialysis: the desert halophilic bacterial cells obtained in step (B) are treated by electrodialysis to obtain tetrahydromethyl pyrimidine carboxyl...

preparation example 3

[0092] This preparation example prepares a kind of hydrolyzed red algae extract, the preparation method of described hydrolyzed red algae extract comprises the following steps:

[0093] (a) Extraction: wash, crush and pass through a 100-200 mesh sieve to obtain the red algae powder; add water to the red algae powder and perform an extraction at 70°C, and the time for the first extraction is 10 hours , the mass ratio of the water and the red algae powder is 20:1, the primary extract is obtained, the primary extract is filtered and then concentrated, then the volume ratio concentration is added to an aqueous ethanol solution of 80% for secondary extraction, and the precipitate is left to stand, Obtain red algae polysaccharide crude material;

[0094] (b) Hydrolysis: after dissolving the crude red algae polysaccharide obtained in step (a) with water, add 30wt% hydrogen peroxide aqueous solution, and mix and stir at 50°C for 1 hour to obtain a hydrolyzed red algae extract;

[009...

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Abstract

The invention provides a composition for repairing a skin barrier and a preparation method and application of the composition. The composition comprises a crithmum maritimum callus culture filtrate, tetrahydromethyl pyrimidine carboxylic acid and a hydrolyzed red alga extract. The composition for repairing the skin barrier is capable of strengthening the skin barrier, improving anti-allergy potential of skin and improving micro-ecology of the skin and has the effects of moisturizing the skin, brightening and whitening skin colors, repairing and regenerating the skin, preventing aging and removing wrinkles, preventing oxidation and protecting the skin, preventing allergy and relieving the skin and improving skin immunity.

Description

technical field [0001] The invention belongs to the technical field of cosmetics, and in particular relates to a composition for repairing skin barrier, a preparation method and application thereof. Background technique [0002] Healthy skin can effectively retain moisture, thereby maintaining good elasticity and lustrous appearance of the skin. However, the skin is affected by the living environment and its own physiological conditions. The skin may have skin problems such as sensitivity, dryness and peeling, excessive oil secretion, pigmentation, sagging and aging skin, and red blood. The main reason is that the skin barrier is damaged. The skin barrier is a protective structure jointly constructed by the stratum corneum and the sebum membrane. It can not only buffer physical and chemical stimulation, effectively inhibit the growth of bacteria, block the damage of bacteria, viruses, and fungi to the skin, but also lock in moisture and prevent moisture from evaporating. , ...

Claims

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Application Information

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IPC IPC(8): A61K8/99A61K8/9717A61K8/49A61Q19/08A61Q19/00A61Q19/02A61Q17/00
CPCA61K8/4953A61K8/99A61K2800/5922A61Q17/005A61Q19/00A61Q19/005A61Q19/02A61Q19/08A61K8/9717
Inventor 范玉菡温伟红莫霖霭徐洁琼
Owner 广州一一生物技术有限公司
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