Biomechanical mandible scaffold and preparation method of micro-nano hierarchical permeable titanium-niobium surface

Abstract

The invention discloses a biomechanical mandible scaffold and a preparation method of a micro-nano hierarchical permeable titanium-niobium surface. The material of the mandible scaffold has a gradientstructure, and the mandible scaffold comprises an alloy matrix and a porous surface, wherein the alloy matrix is a titanium-niobium-based beta-series alloy material and the porous surface is a micro-nano hierarchical permeable titanium-niobium surface. The biomechanical mandible scaffold has the high-strength and low-modulus alloy matrix and the porous surface, the modulus is further reduced through the porous structure, the morphology beneficial to osteoblast adhesion is formed, and the constructed mandible scaffold better conforms to biomechanical characteristics and has surface osteogenicactivity.

Description

technical field [0001] The invention relates to the technical field of oral and maxillofacial restoration and reconstruction, in particular to a biomechanical mandibular support and a method for preparing a titanium-niobium surface with micro-nano graded permeability on the surface of an alloy matrix of the mandibular support. Background technique [0002] At present, mandibular defect repair methods include autologous bone transplantation and heterogeneous material transplantation, etc. However, there are defects in simple autologous bone transplantation and all-heterogeneous material transplantation. Simple autologous bone transplantation has problems such as insufficient autologous bone mass, damage to the donor site, and difficult operation. The most widely studied all-heterogeneous implant is pure titanium. [0003] However, due to the high elastic modulus of the pure titanium material, the fully heterogeneous mandible has poor bonding ability with the surrounding bone...

AI Technical Summary

Problems solved by technology

[0003] However, due to the high elastic modulus of the pure titanium material, the fully heterogeneous mandible has poor bonding ability with the surrounding bone tissue and soft tissue, and there are still problems such as exposure of the graft to the oral cavity, poor osseointegration, and graft failure during the clinical process.

During mandibular reconstruction, the grafted bone block and the mandibular stump are fixed by a titanium plate. However, since the elastic modulus of pure titanium is significantly higher than that of the mandible, it is easy to cause stress shielding phenomenon, resulting in insufficient stress of the grafted bone and absorption.

[0004] In order to overcome the insufficient autologous bone mass and the mechanical and biocompatibility defects of pure metal materials, some scholars have designed a special titanium mesh combined with iliac or fibular cancellous bone particles and bone marrow for mandibular reconstruction. This scheme can avoid the stress shielding effect, however. Its significant disadvantages include: due to the high biological stress of the mandible, the structural design strength of the titanium mesh is insufficient, and it is prone to deformation during the stress process; moreover, the free non-vascularized cancellous bone has a high postoperative absorption rate and poor anti-infection ability, and long-term not effectively

Images