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Anti-dandruff scalp essence containing rose fermentation liquor and preparation method of essence

A technology of fermentation broth and rose, which is applied in medical preparations containing active ingredients, preparations for skin care, hair care, etc., can solve problems such as emergence of drug resistance, loss of efficacy, and imbalance of scalp flora.

Active Publication Date: 2020-11-10
上海洁士宝日化集团有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] The currently used anti-dandruff ingredients are mainly designed for Malassezia colonized on the scalp, but the inhibition of a single flora may lead to rapid emergence of drug resistance and loss of efficacy, and may also make the scalp flora more unbalanced, causing other problems

Method used

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  • Anti-dandruff scalp essence containing rose fermentation liquor and preparation method of essence
  • Anti-dandruff scalp essence containing rose fermentation liquor and preparation method of essence
  • Anti-dandruff scalp essence containing rose fermentation liquor and preparation method of essence

Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0051] The embodiment of the present invention also relates to the preparation method of the anti-dandruff scalp essence, comprising the following steps:

[0052] (1) Mix pure water and acrylic acid (ester) / C10-30 alkanol acrylate crosslinked polymer evenly to obtain phase A for later use;

[0053] Mix denatured ethanol, panthenol, aminomethyl propanol, sodium hyaluronate, rose fermented liquid and allantoin evenly to obtain phase B for later use;

[0054] Mix ethylhexylglycerin and phenoxyethanol evenly to obtain phase C for later use;

[0055] The amount of pure water in phase A and phase B can be distributed as follows: the pure water in phase A accounts for 40% to 55% of the total mass of pure water, and the remaining pure water is added to phase B;

[0056] (2) Turn on the stirring function of the stirring pot, add the pure water in phase A into the stirring pot, then add acrylic acid (ester) / C10-30 alkanol acrylate crosslinked polymer, heat to 70-75°C and stir Mix well...

preparation example 1

[0085] 1) Rose fermentation substrate preparation: crush dried rosebuds and pass through a 100-mesh sieve, add water to prepare a mixed solution with a mass concentration of 10%, and sterilize at 121° C. for 15 minutes to obtain a rose fermentation substrate.

[0086] 2) Strain activation: Dip Bacillus natto CICC 10262 with a sterilized bamboo stick, streak on the solid activation medium according to the plate streak method, and invert aerobic culture in a constant temperature incubator at 37°C for 15 to 20 hours. The activated Bacillus natto CICC 10262 strain was obtained.

[0087] Dip Lactobacillus bulgaricus CICC 20271 with a sterilized bamboo stick, draw a line on the solid activation medium according to the plate streaking method, and culture it upside down in a constant temperature incubator at 37°C for 15-20 hours to obtain the activated Lactobacillus bulgaricus CICC20271 strain .

[0088] Saccharomyces cerevisiae CICC 1252 was dipped with sterilized bamboo sticks, str...

Embodiment 1

[0127] Examples 1-7 and Comparative Examples 1-2 changed the B phase components and addition amount, and other operation steps and testing process were the same as Example 1, and the specific setting methods are shown in Table 5.

[0128] table 5

[0129]

[0130]

[0131] Among them, the meaning of "the remaining amount of pure water" is: the total mass of the anti-dandruff scalp essence is counted as 100 parts, and the raw materials other than pure water in phase B, as well as phase A and phase C are subtracted from 100 parts, and the rest is It is the weight part of pure water in B phase.

[0132] Scalp use test

[0133] A total of 80 volunteers with mild dandruff problems in the age range of 18-60 years old were selected, both male and female, aged between 18-60 years old. The above-mentioned volunteers were randomly divided into 8 groups, 10 people in each group. Among them, groups 1 to 5 are experimental groups, which use the anti-dandruff scalp essence prepar...

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Abstract

The invention provides an anti-dandruff scalp essence containing rose fermentation liquor. The rose fermentation liquor is rich in polysaccharide, flavone and amino acid. The flavone contained in theessence acts on scalp microorganisms, can selectively inhibit malassezia sp. and staphylococcus sp. without prejudicing the growth of propionibacterium sp., and therefore, the scalp flora is balanced.The polysaccharide contained in the essence can keep the scalp moist, and the amino acid can enhance the scalp barrier. Therefore, the anti-dandruff scalp essence can adjust scalp micro-ecology, andimprove scalp health from multiple dimensions, thereby achieving the effects of removing dandruff and nourishing the scalp.

Description

technical field [0001] The invention relates to the technical field of light chemical industry, in particular to an anti-dandruff scalp essence containing rose fermented liquid and a preparation method of the anti-dandruff scalp essence. Background technique [0002] Dandruff is a common disease. According to incomplete statistics, the prevalence of dandruff in post-pubertal populations is 50% worldwide, and its causes and pathogenesis are very complicated. At present, most studies believe that microbiological factors, sebaceous gland secretion and individual susceptibility are the three most important factors in the occurrence of dandruff. [0003] Among them, microbiological factors and local immune response played a major role in the pathogenesis of dandruff. There are many microorganisms distributed on the human skin, among which the fungi distributed on the scalp are mainly Malassezia sp., and the bacteria are mainly Staphylococcus sp. and Propionibacterium sp. [000...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/9789A61Q5/00A61Q5/12A61Q17/00A61P31/02A61P31/04
CPCA61K8/9789A61Q5/006A61Q5/12A61Q17/005A61P31/02A61P31/04A61K2800/782A61K2800/85
Inventor 张启清余海励杨水波孙绪友
Owner 上海洁士宝日化集团有限公司
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