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Preparation method and application of traditional Chinese medicine gel for preventing and treating allergic rhinitis

A technology for allergic rhinitis and gel, which is applied in the field of preparation of traditional Chinese medicine gel, can solve the problems of low extraction ratio, large destruction of active ingredients, and low extraction rate of active ingredients, so as to improve nasal symptoms, have good nasal cavity affinity, Relieve nasal dryness

Inactive Publication Date: 2020-11-13
武汉润禾生物医药有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The traditional products are comfrey ointment or compound comfrey ointment. The method of use is high-temperature frying and extraction. The extraction ratio is relatively low, and the active ingredients are greatly destroyed at high temperatures. Most of the comfrey extracts on the market are water-free or ethanol-extracted. substances, the extraction rate of active ingredients is low

Method used

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  • Preparation method and application of traditional Chinese medicine gel for preventing and treating allergic rhinitis
  • Preparation method and application of traditional Chinese medicine gel for preventing and treating allergic rhinitis
  • Preparation method and application of traditional Chinese medicine gel for preventing and treating allergic rhinitis

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0039] DUT:

[0040] A gel for preventing and treating allergic rhinitis, prepared by the following method:

[0041] The main active ingredients of the gel are proportioned by weight: Mint (Mentha haplocalyx Briq.) 2.0, Artemisia carvifolia Buch.-Ham.ex Roxb. Hort. Beng. 4.0, Artemisia argyi LevL. et Vant.) 4.0, comfrey (Arraa Guttata Bunge) 4.0, hive (Polistes olivaceous (DeGeer) hive) 2.0, cork (Phellodendron chinense Schneid.) 2.0.

[0042] Step 1: Remove impurities and dust from mint, Artemisia annua, Artemisia annua, Comfrey, Comfrey, Phellodendron cork, and add them into the traditional Chinese medicine extraction tank.

[0043] Step 2: Add medicinal grade sesame oil whose weight is 3 times of the total weight of the medicinal materials in step 1 into the extraction tank, stir at 30 rpm for 2 minutes, so that the medicinal materials and the solvent are evenly mixed.

[0044] Step 3: Heat the extraction tank to 90°C, let it stand for extraction for 4 hours, filter, and ...

Embodiment 2

[0069] A gel for preventing and treating allergic rhinitis, prepared by the following method:

[0070] The main active ingredients of the gel are proportioned by weight: Mint (Mentha haplocalyx Briq.) 1.0, Artemisia carvifolia Buch.-Ham.ex Roxb. Hort. Beng. 3.0, Artemisia argyi LevL. et Vant.) 3.0, Comfrey (Arraa Guttata Bunge) 3.0, Polistes olivaceous (DeGeer) 1.0, Phellodendron chinense Schneid. 1.0.

[0071] The preparation steps and parameters are the same as the preparation steps of the sample to be tested in Example 1, and the use method is the same as in Example 1.

[0072] Test results: The changes in symptoms of allergic rhinitis after use by 20 people are shown in the table below:

[0073]

[0074]

[0075] Summary: There are a total of 20 volunteers in the test group, ranging in age from 8 to 42 years old. Results 30% of the symptoms were alleviated, 70% of the symptoms of sneezing completely disappeared; 20% of the symptoms of runny nose were relieved, and ...

Embodiment 3

[0077] A gel for preventing and treating allergic rhinitis, prepared by the following method:

[0078] The main active ingredients of the gel are proportioned by weight: Mint (Mentha haplocalyx Briq.) 2.0, Artemisia carvifolia Buch.-Ham.ex Roxb. Hort. Beng. 3.5, Artemisia argyi LevL. et Vant.) 3.5, Comfrey (Arraa Guttata Bunge) 3.5, Polistes olivaceous (DeGeer) 1.5, Phellodendron chinense Schneid. 1.5.

[0079] The weight ratio of the extract, polyethylene sodium, beeswax, fumed silica, bentonite, methylparaben and propylparaben in step 5 during the preparation process is 92, 2.0, 2.0, 1.0, 1.0, 0.1, 0.2 .

[0080]The rest of the preparation steps and parameters are the same as the preparation steps of the test product in Example 1, and the use method is the same as that in Example 1.

[0081] The preparation steps and parameters are the same as the preparation steps of the test product in Example 1, and the use method is the same as that in Example 1

[0082] Test results:...

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PUM

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Abstract

The invention belongs to the field of traditional Chinese medicine preparations, and particularly relates to a preparation method and an application of traditional Chinese medicine gel for preventingand treating allergic rhinitis. The gel comprises the following main effective components: mint, sweet wormwood herb, folium artemisiae argyi, lithospermum, honeycomb and golden cypress. The traditional Chinese medicine is extracted by adopting sesame oil, effective components of traditional Chinese medicinal materials in a prescription can be completely extracted, the problems of low extraction rate and large loss of effective component volatile oil and fat-soluble components and excessive impurity components such as sugar and protein in the traditional Chinese medicine in the extraction process of a traditional method are solved, and the product is high in effective component content and low in impurity content; other auxiliary materials are directly added on the basis of an extract withsesame oil as a solvent to prepare the gel, and the prepared gel has good affinity with the nasal cavity, can effectively isolate allergens, dredge orifices and inhibit bacteria and fungi in the nasal cavity, and plays a role in preventing allergic rhinitis and improving nasal cavity ventilation.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicine preparations, and in particular relates to a preparation method and application of a traditional Chinese medicine gel for preventing and treating allergic rhinitis. Background technique [0002] The occurrence of allergic rhinitis is related to many factors such as genetics, environment, and diet. The traditional treatment methods include the use of antihistamine drugs to improve nasal symptoms, allergen desensitization treatment, and nasal cleaning agents. [0003] Western medicine treatment of rhinitis is the most commonly used antihistamine antiallergic drugs, desensitization and nasal cleaning. There are certain defects in the above methods. For example, the use of antihistamine antiallergic drugs to treat allergic rhinitis has certain side effects. After long-term use, there is dependence, the nasal cavity is more likely to dry, and the duration is short, so long-term use is requir...

Claims

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Application Information

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IPC IPC(8): A61K36/756A61K9/06A61P11/02A61P37/08
CPCA61K9/0043A61K9/06A61K35/64A61K36/282A61K36/30A61K36/534A61K36/756A61K47/32A61K47/44A61K2236/35A61P11/02A61P37/08A61K2300/00
Inventor 王线周清郑和国
Owner 武汉润禾生物医药有限公司