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Super-amphiphobic stainless steel wire mesh and preparation process and application thereof

A preparation process, stainless steel technology, applied in metal material coating process, biochemical equipment and methods, artificial cell constructs, etc., can solve the problem that cannot meet the requirements of forward cultivation of large-sized multicellular spheres, super-amphiphobic surface machinery Poor stability, complex multi-level structure design process and other problems, to achieve the effect of low raw material price, low adhesion characteristics, and reduced contact area

Inactive Publication Date: 2021-03-19
SHANGHAI DIANJI UNIV
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] In order to solve the problem of poor mechanical stability of the superamphiphobic surface prepared by the prior art, complex multi-level structure design process, high cost, and inability to meet the requirements of forward cultivation of large-sized multicellular spheroids, the first purpose of the present invention is to provide a superamphiphobic surface The preparation process of amphiphobic stainless steel wire mesh provides new materials and new methods for the fields of biomedicine and anti-tumor drug screening

Method used

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  • Super-amphiphobic stainless steel wire mesh and preparation process and application thereof
  • Super-amphiphobic stainless steel wire mesh and preparation process and application thereof
  • Super-amphiphobic stainless steel wire mesh and preparation process and application thereof

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Embodiment 1

[0040] Prepare super-amphiphobic stainless steel wire mesh, the steps are:

[0041] The first step: preparation of electrodeposited PEDOT template. The working electrode is stainless steel wire mesh (305 mesh, 3×6cm 2 ), first use deionized water, absolute ethanol and 1M NaOH solution to ultrasonically clean the stainless steel wire mesh, then activate it with 1M hydrochloric acid for 20min, then wash the stainless steel wire mesh with deionized water, dry it in the air, and electrodeposit the PEDOT film The amount is controlled at 150-210mC / cm 2 , as the first-level template for chemical vapor deposition in the next step.

[0042] Step 2: Chemical vapor deposition of SiO on the first-level template 2 coating. The PEDOT film coating prepared around the stainless steel wire mesh was placed in a closed desiccator, and tetraethoxysilane TEOS was chemically vapor deposited at room temperature for 48 hours, and calcined in air at 500 ° C for 2 hours to remove the PEDOT template...

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Abstract

The invention discloses a super-amphiphobic stainless steel wire mesh and a preparation process and application thereof, and belongs to the field of biomedical materials. The preparation method comprises the following steps that by taking a stainless steel wire mesh as a working electrode, electrodeposition is carried out to obtain a PEDOT film with a porous nano structure, chemical vapor deposition is carried out on tetraethoxysilane to obtain a porous SiO2 coating, chemical vapor deposition is carried out on soot and tetraethoxysilane to obtain a porous SiO2 aerogel layer, and fluorinating is carried out to obtain a super-amphiphobic SiO2 aerogel coating. The obtained contact angle CA is larger than or equal to 150 degrees and the rolling angle SA is smaller than or equal to 10 degrees,the super-amphiphobic stainless steel wire mesh can resist oil stain adhesion and biological adhesion at the same time, has good comprehensive performance such as heat stability, super-amphiphobic performance, mechanical stability and acid / alkali resistance, and can be used for screening biological antibacterial materials or anti-tumor drugs.

Description

technical field [0001] The invention relates to a super-amphiphobic stainless steel wire mesh that resists oil stain adhesion and bioadhesion, its preparation process and application, and belongs to the field of biomedical materials. Background technique [0002] Constructing a real tumor model in vitro and studying the complex oxygen, nutrients, and spatial distribution characteristics of drugs in tumor multicellular spheroids play an important role in important biomedical fields such as controlling tumor development and developing anticancer drugs. So far, people have developed a variety of multicellular spheroid culture methods, such as hydrogel static culture, centrifugal culture, and hanging drop culture. These culture methods have obtained a large number of multicellular spheroids with controllable size. Large-scale multicellular spheroids and simultaneous online observation and research still face the following technical problems: (1) The method of hydrogel cultivatio...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): C25D9/02C23C16/40C23C16/04C12N5/071C12N5/09C12Q1/02C12Q1/18
CPCC25D9/02C23C16/402C23C16/042C12N5/0062C12N5/0693C12N5/0631G01N33/5011G01N33/5088C12N2513/00C12N2503/02
Inventor 徐连仪冉准李荣斌杜浩明周丽娜李雪改徐一亭
Owner SHANGHAI DIANJI UNIV
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