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Traditional Chinese medicine plaster for promoting wound healing and reducing scar formation and preparation method thereof

A technology for wound healing and traditional Chinese medicine ointment, which is applied in the directions of medical preparations, pharmaceutical formulas, and drug combinations containing active ingredients, and can solve the problems of slow effect, high treatment price, and large side effects.

Active Publication Date: 2022-07-08
SHANDONG UNIV OF TRADITIONAL CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Chronic wound healing and scar residue after healing have always been an international medical problem, mainly including surgical resection, laser removal, silicone therapy, and compression therapy. and economic pressure, so early intervention in the scar formation stage is of great significance to reduce scar formation

Method used

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  • Traditional Chinese medicine plaster for promoting wound healing and reducing scar formation and preparation method thereof
  • Traditional Chinese medicine plaster for promoting wound healing and reducing scar formation and preparation method thereof
  • Traditional Chinese medicine plaster for promoting wound healing and reducing scar formation and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0033] Example 1 Preparation of traditional Chinese medicine ointment for promoting wound healing and reducing scarring

[0034] It is prepared by the following raw materials in parts by weight: 4 parts of Salvia miltiorrhiza, 1 part of honeysuckle, 2 parts of Duhuo, Forsythia suspensa, mulberry white skin, 2 parts of Achyranthes, and 15 parts of pure suet.

[0035] The preparation method is:

[0036] (1) Take Danshen decoction pieces (dried to constant weight in advance), pulverize (pass through an 80-mesh sieve), add an appropriate amount of water to moisten and mix, and set aside;

[0037] (2) get honeysuckle, solitary root, forsythia, mulberry white bark and Achyranthes, pulverize (pass 80 mesh sieve), add an appropriate amount of 95% ethanol solution (volume percent), decocted until the ethanol is completely volatilized, to obtain medicinal residues, for use;

[0038] (3) Mix the medicinal residue in step (1) with the evenly moistened Salvia miltiorrhiza powder in step (...

Embodiment 2

[0039] Example 2 Preparation of traditional Chinese medicine plaster for promoting wound healing and reducing scarring

[0040] It is prepared from the following raw materials by weight: 3 parts of salvia miltiorrhiza, 2 parts of honeysuckle, 3 parts of solitary, 3 parts of forsythia, 3 parts of mulberry white skin, 3 parts of hyssopus, and 12 parts of suet.

[0041] Others are the same as in Example 1.

Embodiment 3

[0042] Example 3 Preparation of traditional Chinese medicine plaster for promoting wound healing and reducing scarring

[0043] It is prepared from the following raw materials by weight: 2 parts of salvia miltiorrhiza, 2 parts of honeysuckle, 4 parts of solitary, 4 parts of forsythia, 4 parts of mulberry white skin, 4 parts of hyssopus, and 10 parts of suet.

[0044] Others are the same as in Example 1.

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Abstract

The invention discloses a traditional Chinese medicine ointment for promoting wound healing and reducing scar formation. 2 to 4 parts, 2 to 4 parts of Morus alba, 2 to 4 parts of Achyranthes, and 10 to 15 parts of suet. The traditional Chinese medicine ointment of the present invention has a significant effect on promoting wound healing and reducing scar formation. It can increase the level of tumor necrosis factor by affecting the secretion of related growth factors (EGF, VEGF-α, TGF-β, etc.), and promote the accumulation of neutrophils and macrophages, thereby reducing the inflammatory response process and avoiding long-term wounds. Inflammatory state; and resist bacterial infection (Staphylococcus aureus, Pseudomonas aeruginosa, Proteus, etc.), to promote wound healing, reduce excessive proliferation of fibroblasts in regenerated tissue, and achieve the purpose of reducing scarring in the wound healing stage.

Description

technical field [0001] The invention relates to a traditional Chinese medicine plaster for promoting wound healing and reducing scar formation and a preparation method thereof, belonging to the technical field of traditional Chinese medicine research and development. Background technique [0002] Wound healing is the physiological response of damaged skin, including four stages of hemostasis, inflammation, regeneration, and remodeling. The intractable scars generated after wound healing seriously affect the physical and mental health of patients. Intractable scars are mainly caused by excessive angiogenesis, excessive contraction of granulation tissue and excessive proliferation of fibroblasts. Especially the skin wounds of patients with burns and scalds and hyperglycemia usually heal slowly, and the stubborn scars are more serious. Chronic wound healing and residual scar after healing has always been an international medical problem, mainly including surgical excision, las...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/634A61K9/06A61K47/44A61P17/02
CPCA61K36/537A61K36/355A61K36/232A61K36/634A61K36/605A61K36/21A61K9/06A61K9/0014A61K47/44A61P17/02A61K2236/333A61K2300/00Y02A50/30
Inventor 刘谦
Owner SHANDONG UNIV OF TRADITIONAL CHINESE MEDICINE
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