Core-shell structure titanium-nickel medical implant based on elastic modulus regulation and control, 4D printing forming method and application

Abstract

The invention discloses a core-shell structure titanium-nickel medical implant based on elastic modulus regulation and control, a 4D printing forming method and application. The preparation method comprises the steps of implant service environment stress analysis, elastic modulus controllable core-shell structure design, 4D printing process parameter design based on elastic modulus regulation and control and forming. The principle is based on the elastic modulus difference between austenite and martensite, the 4D printing process parameters are regulated and controlled to achieve customization of the elastic modulus, and the elastic modulus controllable core-shell structure titanium-nickel medical implant is prepared. When the complex titanium-nickel medical implant is formed, customization of the elastic modulus of any part, making contact with the human skeleton, of the implant can be achieved, the elastic modulus of medical implant alloy is effectively reduced, the stress shielding problem is solved, the application range is wide, and the method can be used for preparing various medical implants (such as femoral head, hip and knee joint implants, spinal column implants and the like) meeting biomechanical compatibility.

Description

technical field [0001] The invention belongs to the fields of additive manufacturing, 3D / 4D printing technology, biomedical functional materials and smart materials, and specifically relates to a core-shell structure nickel-titanium medical implant based on elastic modulus regulation and a 4D printing forming method and application. Background technique [0002] The statistics of big clinical medical data show that although the biomedical implant alloys (such as CoCr, pure Ti, Ti6Al4V alloy) prepared by additive manufacturing can achieve accurate reconstruction and shaping, they have a large elastic modulus matching with human bones. Poor, that is, there is a "stress shielding effect" between the elastic modulus of implants (CoCr alloy 240GPa, pure Ti 100GPa, Ti6Al4V alloy 110GPa) and human bone elastic modulus (10-30GPa) (Adv. Eng. Mater., 2019, 1801215 ). As a result, the Ti6Al4V implant cannot perfectly match the elastic modulus of the joint part of the human bone, resul...

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Problems solved by technology

At present, 4D printing technology is deeply expanding the engineering application field of titanium-nickel alloy parts and products. However, at present, 4D printing titanium-nickel alloy mainly involves heat treatment process, energy source parameters and the introduction of second phase basic research (Prog. Mater. Sci. 83 (2016) 630-663.), the research on the customized structural design and function realization of 4D printed titanium-nickel alloy components is not systematic enough

[0005] Based on the common "stress shielding effect" of implants and the incomplete research on customized structural design and function realization, this patent proposes the concept of regulating the phase composition and elastic modulus of 4D printed titanium-nickel alloys, aiming at providing The tissue performance regulation and structural design of medical functional materials provide a useful reference and reference

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