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Anti-allergy traditional Chinese medicine formula fermentation product, preparation method and application thereof in cosmetics

A technology for fermented products and traditional Chinese medicine components, which is applied in cosmetics, cosmetic preparations, cosmetic preparations and other directions, and can solve the problems of insufficient effect, inability to combine, and insufficient mixing.

Active Publication Date: 2021-09-10
RAYTING BIOTECHNOLOGY CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] In the prior art, the Shumin compound liquid formed by compounding various plant extracts may have the problem of insufficient mixing between various liquids during the compounding process of several kinds of extracts, and there is no The use of related mixed media results in that the compound solution cannot combine the effects of each component well and cannot fully exert the effects of each component

Method used

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  • Anti-allergy traditional Chinese medicine formula fermentation product, preparation method and application thereof in cosmetics
  • Anti-allergy traditional Chinese medicine formula fermentation product, preparation method and application thereof in cosmetics
  • Anti-allergy traditional Chinese medicine formula fermentation product, preparation method and application thereof in cosmetics

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Experimental program
Comparison scheme
Effect test

Embodiment 1

[0047] 1. Selection and combination of plants

[0048] 1.1 Database screening

[0049] In the TCMSP database, 361 kinds of plants are obtained through screening with atopic dermatitis (Atopic Dermatitis) as the key word, including the Chinese herbal medicine plant in claim 1. Further search for plant extracts available for cosmetics through the "Catalogue of Names of Used Cosmetic Raw Materials (2021 Edition)", and finally locked 30 kinds of plants. These 30 plants and Chinese herbal medicine plants can be purchased from Beijing Tongrentang, and 10 parts of individual Chinese medicines are fermented to screen for NO (nitric oxide) inhibitory activity.

[0050] 1.2 Screening of NO inhibitory activity

[0051] It has been reported in the literature that NO free radicals play a key role in skin inflammation, can up-regulate iNOS, and are also related to inflammatory factors such as IL-1beta, IL-6, and TNF-alpha.

[0052] NO is a common free radical in polluted air and smog, so...

Embodiment 2

[0077] Preparation of a kind of anti-allergic fermented product of traditional Chinese medicine (Ⅰ)

[0078] A fermented traditional Chinese medicine formula with anti-allergic properties is prepared from the following Chinese medicinal material components in parts by weight: 10 parts of centella asiatica, 10 parts of mugwort leaves, and 10 parts of gardenia.

[0079] The preparation method is as follows:

[0080] (1) Cultivation of seed yeast: Yeast was inoculated in YPD medium (g / L) sterilized at 121°C for 20 minutes, with peptone 20, yeast powder 10, glucose 20, pH 6.5, pure water 1.0L ratio In the liquid culture medium in the column, culture at 220rpm, 30°C for 24h, when the OD600 reaches 10, set aside.

[0081] (2) Preparation of medium for traditional Chinese medicine prescriptions: removing impurities, washing, drying, and pulverizing each raw material of Chinese medicines to 60-80 meshes, and mixing according to the desired ratio to obtain a Chinese medicine compositi...

Embodiment 3

[0086] Preparation of a kind of anti-allergy fermented product of traditional Chinese medicine (Ⅱ)

[0087] An anti-allergic traditional Chinese medicine fermented product is prepared from the following Chinese medicinal material components in parts by weight: 7.5 parts of centella asiatica, 15 parts of mugwort leaves, and 7.5 parts of gardenia.

[0088] The preparation method is as follows:

[0089] (1) Cultivation of seed yeast: Yeast was inoculated in YPD medium (g / L) sterilized at 121°C for 20 minutes, with peptone 20, yeast powder 10, glucose 20, pH 6.5, pure water 1.0L ratio In the liquid medium of the column, culture at 220 rpm, 30 degrees for 24 hours, when the OD600 reaches 10, it is ready for use.

[0090](2) Preparation of medium for traditional Chinese medicine prescriptions: removing impurities, washing, drying, and pulverizing each raw material of Chinese medicines to 60-80 meshes, and mixing according to the desired ratio to obtain a Chinese medicine compositio...

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Abstract

The invention discloses an anti-allergy traditional Chinese medicine formula fermentation product, a preparation method and application thereof in cosmetics. The traditional Chinese medicine formula is finally determined through scientific proportioning of various raw materials and multiple efficacy experiments, which comprises 1-30 parts of centella asiatica, 1-30 parts of folium artemisiae argyi and 1-30 parts of cape jasmine. According to the traditional Chinese medicine formula fermentation product, saccharomycetes and effective components of Chinese herbal medicine are well fused, so that the traditional Chinese medicine formula fermentation product has high safety, high anti-allergy activity and good cell repairing and protecting capacity and can be applied to skin care products with the anti-allergy effect.

Description

technical field [0001] The invention belongs to the fields of plant application and cosmetics, and in particular relates to a traditional Chinese medicine prescription fermented product for anti-allergy, a preparation method and its application in cosmetics. Background technique [0002] Sensitive skin is a type of problem skin that can be found in any skin type. Just like all skin types may have aging skin, acne skin, etc. The main characteristics of sensitive skin are dry skin, easy to tighten and redness, itching, desquamation or even burning and stinging sensations can occur after slight stimulation, and bad mood or mental symptoms can occur in severe cases. Compared with normal skin, sensitive skin has the characteristics of barrier function damage or abnormal nerve function, and it is more difficult to resist the invasion of external stimuli and allergens, and it is prone to a series of skin inflammatory reactions caused by irritation or allergies, and then further da...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/744A61P17/00A61P37/08A61K8/9789A61Q19/00A61Q19/08A61P17/18
CPCA61K36/23A61K36/282A61K36/744A61P17/00A61P37/08A61K8/9789A61Q19/005A61Q19/08A61P17/18A61K2236/19A61K2800/782A61K2800/5922A61K2800/85A61K2300/00
Inventor 杜养标龙瑞雪赵炳天
Owner RAYTING BIOTECHNOLOGY CO LTD
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