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Corneal contact lens nursing composition as well as preparation method and application thereof

A technology for contact lenses and compositions, applied in the directions of botanical equipment and methods, applications, chemicals for biological control, etc., can solve the problems of aging and damage of contact lenses, short effective action time, and influence on sterilization effect, etc., To achieve the effect of good sterilization, enhanced bactericidal effect, and short treatment time

Inactive Publication Date: 2021-11-09
XI AN JIAOTONG UNIV +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although hydrogen peroxide has a good bactericidal effect, the residual H 2 o 2 Has an aging and destructive effect on contact lenses and is irritating to the eyes
At the same time, using a platinum ring for neutralization, H 2 o 2 The effective action time is short, which affects its bactericidal effect

Method used

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  • Corneal contact lens nursing composition as well as preparation method and application thereof
  • Corneal contact lens nursing composition as well as preparation method and application thereof
  • Corneal contact lens nursing composition as well as preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1-7

[0049] The bactericidal care solution of embodiment 1-7 is shown in the table below

[0050]

[0051] The reduction neutralizer liquid dosage form component of embodiment 1-7 is shown in the table below

[0052]

[0053] The reduction neutralizer solid dosage form components of embodiment 1-7 are shown in the table below

[0054]

[0055]

[0056] The disinfection effect of embodiment 1-7

[0057]

[0058]

[0059] According to the national standard GB19192-2003 "Hygienic Requirements for Contact Lens Care Solution", Appendix A disinfection effect test method was used to test the bacteria elimination rate. Select Candida albicans (ATCC 10231) ( figure 1 ), Escherichia coli (ATCC 8739) ( figure 2 ), and Staphylococcus aureus (ATCC 6538) ( image 3 ) is a representative strain, and the neutralizing agent is the reducing neutralizing agent liquid dosage form selected for use, and the steps are carried out according to appendix A, and Example 2 is selected t...

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Abstract

The invention discloses a corneal contact lens nursing composition as well as a preparation method and application thereof. The corneal contact lens nursing composition comprises a sterilization nursing solution and a reduction neutralizer, and the pH value of the sterilization nursing solution is 3.0-7.0. The sterilization nursing solution is prepared from the following components in percentage by mass: 0.05 wt% to 0.8 wt% of an iodine complex, 0.1 wt% to 0.8 wt% of potassium iodide, 0.001 wt% to 0.005 wt% of proteolytic enzyme, 0.01 wt% to 0.10 wt% of a nonionic surfactant, 0 to 0.80 wt% of an osmotic pressure regulator and 98.295 wt% to 99.839 wt% of H2O. The reduction neutralizer is in a solid dosage form or a liquid dosage form. The corneal contact lens nursing composition is shorter in treatment time and better in safety.

Description

technical field [0001] The invention relates to the field of iodine care solution, in particular to a corneal contact lens care composition, a preparation method and an application. Background technique [0002] Myopia is the most common type of refractive error eye disease. Compared with glasses, contact lenses (contact lenses) are more convenient, comfortable, aesthetically pleasing and have realistic images. Therefore, its market share is increasing year by year. Contact lenses include orthokeratology lenses, rigid gas permeable contact lenses and soft contact lenses. Contact lenses are directly attached to the tear layer of the cornea, providing a larger field of vision, maintaining optical correction in all directions of gaze, eliminating the prism effect of glasses, eliminating oblique astigmatism, and reducing binocular retinal aberrations. Due to the direct contact between the lens and the cornea, conjunctiva, tear film, etc., if the disinfection is improper, it i...

Claims

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Application Information

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IPC IPC(8): A01N59/12A01N63/50A01N25/30A01N25/00A01P1/00A01P3/00
CPCA01N59/12A01N63/50A01N25/30A01N25/00
Inventor 陈炜吴春生杜立萍陈雅婷焦立学
Owner XI AN JIAOTONG UNIV
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