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Full-nutrient dietary composition suitable for Crohn disease and preparation method thereof

A technology for Crohn's disease and complete nutrition, which is applied in the field of complete nutrition dietary composition and its preparation, can solve the problems of small molecular weight, low osmotic pressure, and low antioxidant effect, and achieve the effects of reducing abdominal pain, promoting absorption, and fast absorption rate Effect

Active Publication Date: 2021-11-23
THE FIRST AFFILIATED HOSPITAL OF MEDICAL COLLEGE OF XIAN JIAOTONG UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Existing nutritional preparations have few types of antioxidant nutrients, weak synergistic effect, and low antioxidant effect. Therefore, it is necessary to provide CD patients with a product with a smaller molecular weight, lower osmotic pressure, and easier digestion and absorption. At the same time, add a variety of antioxidant nutrients. Enteral nutrition preparations that synergistically exert the multiplier effect of antioxidants to reduce postoperative oxidative stress and reduce the risk of postoperative infection and complications in CD patients

Method used

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  • Full-nutrient dietary composition suitable for Crohn disease and preparation method thereof
  • Full-nutrient dietary composition suitable for Crohn disease and preparation method thereof
  • Full-nutrient dietary composition suitable for Crohn disease and preparation method thereof

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preparation example Construction

[0027] The invention also discloses a preparation method of a full-nutrition dietary composition suitable for Crohn's disease, which includes the following steps:

[0028] Step 1, the preparation of snow gall polysaccharide: After the snow gall polysaccharide is pulverized, pass through a 100-mesh sieve to obtain a sample and place it in a desiccator for later use; the snow gall powder and water are in a ratio of 1:14-1:18 according to the material-liquid ratio, and the extraction temperature is set to 80-90 ℃, hot water extraction time is set to 1-2h, after repeated extraction 3 times, centrifuge to collect the supernatant; use a rotary evaporator to concentrate the supernatant, the volume and mass of the concentrated supernatant and snow gall powder The ratio is 5g: 100mL; add activated carbon for decolorization, shake and centrifuge to remove the precipitate, add 5 times of chloroform and n-butanol mixture, wherein, the volume ratio of chloroform:n-butanol is 5:1, and shake ...

Embodiment 1

[0039] A full-nutrition dietary composition suitable for Crohn's disease, consisting of the following components in parts by mass: 58 parts of glucose, 57.5×10 -3 16 parts of hydrolyzed whey protein small molecule peptides, 2.25 parts of leucine, 1.86 parts of isoleucine, 1.5 parts of valine, 0.38 parts of glycine, 0.38 parts of histidine, 4 parts of milk fat, medium chain triglycerides 4 parts, 3.5 parts of corn oil, 3 parts of n-3 unsaturated fatty acid, 0.3 part of choline, 0.05 part of taurine, 45×10 -3 Servings, Curcumin 270×10 -3 Servings, Vitamin A 3×10 -4 Servings, Vitamin D7.6×10 -6 0.056 parts of vitamin E, 0.06 parts of vitamin C, 0.76 parts of potassium, 0.11 parts of magnesium, 0.6 parts of calcium, 0.44 parts of phosphorus, 3.6×10 -3 parts, selenium 0.3×10 -4 servings, iron 7 x 10 -3 parts, glutamine 7.5 parts, arginine 3.5 parts, niacin 5×10 -3 servings, pantothenic acid 2×10 -3 parts, vitamin B 1 6×10 -4 parts, vitamin B 2 6×10 -4 parts, vitamin B ...

Embodiment 2

[0047] A full-nutrition dietary composition suitable for Crohn's disease, consisting of the following components in parts by mass: 50 parts of glucose, 75×10 -3 19.2 parts of hydrolyzed whey protein small molecule peptides, 1.2 parts of leucine, 0.93 parts of isoleucine, 0.75 parts of valine, 0.19 parts of glycine, 0.19 parts of histidine, 4.25 parts of milk fat, medium chain triglycerides 4.75 parts, 4 parts of corn oil, 2 parts of n-3 unsaturated fatty acid, 0.2 part of choline, 0.03 part of taurine, 30×10 -3 Servings, Curcumin 153.75×10 -3 servings, vitamin A2.5×10 -4 Servings, Vitamin D 5.8×10 -6 parts, vitamin E 0.047 parts, vitamin C 0.042 parts, potassium 0.66 parts, magnesium 0.1 parts, calcium 0.45 parts, phosphorus 0.32 parts, zinc 3.1×10 -3 parts, selenium 0.23×10 -4 servings, iron 10 x 10 -3 parts, glutamine 10 parts, arginine 5 parts, niacin 4.5×10 -3 parts, pantothenic acid 1.75×10 -3 parts, vitamin B 1 4.75×10 -4 parts, vitamin B 2 4.75×10 -4 parts,...

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Abstract

The invention discloses a full-nutrient dietary composition suitable for the Crohn disease and a preparation method thereof. The full-nutrient dietary composition comprises the following components: glucose, hemsleya amabilis polysaccharide, a whey protein hydrolysate small molecule peptide, leucine, isoleucine, valine, glycine, histidine, milk fat, medium chain triglyceride, corn oil, n-3 unsaturated fatty acid, choline, taurine, hemsleya amabilis polyphenol, curcumin, vitamin A, vitamin D, vitamin E, vitamin C, potassium, magnesium, calcium, phosphorus, zinc, selenium, iron, glutamine, arginine, nicotinic acid, pantothenic acid, vitamin B1, vitamin B2, vitamin B6, vitamin B12, folic acid, iodine, vitamin K1 and biotin. According to the invention, the small molecule peptide is selected, so that the intestinal burden can be relieved, diarrhea can be relieved; and meanwhile, various antioxidant nutrients are added to synergistically take an antioxidant multiplication effect, so that the postoperative oxidative stress reaction is reduced, and the risk of postoperative infection and complications of a patient suffering from the Crohn disease is reduced.

Description

technical field [0001] The invention belongs to the technical field of special diet food, and in particular relates to a full-nutrition diet composition suitable for Crohn's disease and a preparation method thereof. Background technique [0002] Inflammatory bowel disease (IBD) is a non-specific intestinal inflammatory disease with unknown pathogenesis, including Crohn's disease (CD) and ulcerative colitis (Ulcerativecolitis, UC). In recent years, the incidence of IBD has been increasing year by year. The number of patients with IBD in the United States and Europe has reached 1 million and 2.5 million respectively, which has greatly affected social productivity and the quality of life of patients. In recent years, with the westernization of lifestyle, the incidence rate in Asia has gradually increased, reaching 1.05 / 100,000 to 6.67 / 100,000 in different populations, and it has become a global disease. Environmental factors such as smoking, vitamin D deficiency, low-fiber, hi...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A23L33/00A23L33/125A23L33/18A23L33/175A23L33/105
CPCA23L33/40A23L33/125A23L33/18A23L33/175A23L33/105A23V2002/00A23V2200/32A23V2250/0628A23V2250/0626A23V2250/0654A23V2250/0622A23V2250/0624A23V2250/1944A23V2250/1882A23V2250/0644A23V2250/062A23V2250/0606A23V2250/16A23V2250/161A23V2250/1642A23V2250/1626A23V2250/1618A23V2250/1592A23V2250/1578A23V2250/1598A23V2250/2112A23V2250/21A23V2250/2132A23V2250/304A23V2250/55A23V2250/61A23V2250/702A23V2250/71A23V2250/712A23V2250/708A23V2250/7046A23V2250/705A23V2250/7056A23V2250/7042A23V2250/7044A23V2250/7052A23V2250/706A23V2250/7142A23V2250/72
Inventor 宋戈廖侠贾庆安刘昌
Owner THE FIRST AFFILIATED HOSPITAL OF MEDICAL COLLEGE OF XIAN JIAOTONG UNIV
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