Composition with protection effect on blue light induced skin cell injury and use thereof in cosmetics

A technology for skin cells and protection, applied in the field of medical beauty and skin care products, can solve the problem of less products in the epidermal barrier steady state, and achieve significant moisturizing and repairing effects, easy to reproduce, and the effect of reducing ROS

Active Publication Date: 2022-01-04
CHINA PHARM UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] At present, most of the anti-blue light compositions and skin care products on the market start from the perspective of absorbing blue light and anti-photoaging, and study the effect of blue light on the stability of the epidermal barrier. relatively few products

Method used

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  • Composition with protection effect on blue light induced skin cell injury and use thereof in cosmetics
  • Composition with protection effect on blue light induced skin cell injury and use thereof in cosmetics
  • Composition with protection effect on blue light induced skin cell injury and use thereof in cosmetics

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0050] The preparation method of golden ear crude polysaccharide is as follows:

[0051] Step (1), dry and pulverize the fresh Auricularia fruiting bodies to obtain dried Auricularia powder, add 95% ethanol and stir at room temperature for 24 hours according to the solid-liquid ratio of 1:15 (g:mL or kg:L), degrease, and suction filter , the filter cake is dried to obtain a degreased dry powder;

[0052] Step (2), add deionized water to the degreased dry powder obtained in step (1), stir until the dry powder swells, add an appropriate amount of 1mol / L NaOH to adjust pH=5.5, heat up to 50°C, add cellulase and pectinase (the enzyme activity of cellulase is 22U / mg; The enzyme activity of pectinase is 31.3U / mg; The consumption of cellulase is 6%wt of degreasing dry powder; The consumption of pectinase is 4%wt of degreasing dry powder) , 50°C for enzymatic hydrolysis for 30 minutes; then extract in water at 80°C for 1 hour, centrifuge after cooling, take the supernatant, concentra...

Embodiment 2

[0065] A composition having a protective effect on skin cell damage induced by blue light, which is composed of auricularia aureus crude polysaccharide (Example 1) and glucosyl hesperidin in a mass ratio of 1:1.

Embodiment 3

[0067] A composition having a protective effect on skin cell damage induced by blue light, which is composed of auricularia aureus crude polysaccharide (Example 1) and glucosyl hesperidin in a mass ratio of 2:3.

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PUM

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Abstract

The invention discloses a composition with a protection effect on blue light induced skin cell injury. The composition comprises tremella aurantialba crude polysaccharide and glucosyl hesperidin at a mass ratio of (0.01-1):(0.01-4) and more than 1: 1. The composition has a protection effect on keratinocytes injury induced by blue light, can also can promote proliferation and migration of skin keratinocytes after blue light irradiation, relieves delay of skin barrier repair caused by the blue light, and thus promotes repair of skin injury barriers. The invention further discloses use of the composition or the tremella aurantialba crude polysaccharide or the glucosyl hesperidin in preparing cosmetics. The composition or the tremella aurantialba crude polysaccharide or the glucosyl hesperidin and other active ingredients and auxiliary materials are prepared into the cosmetics, internal self-repairing of a skin barrier is facilitated, and the composition has moisturizing, relieving and repairing effects.

Description

technical field [0001] The invention belongs to the technical field of medical beauty and skin care products, and relates to a composition having a protective effect on skin cell damage induced by blue light and its application in cosmetics, in particular to a composition containing aurantium aureus which has a protective effect on skin cell damage induced by blue light Composition of crude polysaccharide and glucosyl hesperidin and its use in the preparation of cosmetics. Background technique [0002] Blue light is a high-energy visible light with a wavelength of 400-500nm, which not only exists in sunlight, but also can be produced by various artificial light sources such as LED lights, fluorescent lights, incandescent lights, TVs, tablets and various displays in smartphones . People use electronic devices such as mobile phones and computers more and more frequently, and even rely on screens. The blue light emitted by these screens will affect the eyes, biological rhythm ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/73A61K8/60A61K8/42A61K8/63A61K8/88A61K8/68A61K8/44A61K8/67A61K8/35A61K8/34A61Q17/04A61Q19/00
CPCA61K8/73A61K8/602A61K8/42A61K8/63A61K8/735A61K8/88A61K8/68A61K8/733A61K8/44A61K8/678A61K8/35A61K8/345A61Q17/04A61Q19/00A61K2800/592A61K2800/522
Inventor 曹崇江尧岚程抒劼
Owner CHINA PHARM UNIV
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