Probiotic composition and preparation method thereof

A composition and technology of probiotics, applied in the field of medicine, can solve the problems of rare oral health care, lack of efficient oral microbe-regulating probiotic preparations, etc.

Pending Publication Date: 2022-01-28
深圳保时健生物工程有限公司
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0021] However, these methods are either symptomatic treatment, or antibiotics are used to fully unify the microorganisms, and some beneficial microorganisms are also inhibited, but there is a lack of efficient oral microbial regulation probiotics
[0022] Many experiments have confirmed that lactic acid bacteria are related to intestinal health, and most clinical and experimental data focus on the prevention of gastrointestinal infections, and relatively few studies focus on oral health care

Method used

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  • Probiotic composition and preparation method thereof
  • Probiotic composition and preparation method thereof
  • Probiotic composition and preparation method thereof

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Experimental program
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Effect test

Embodiment 1-5

[0043] Embodiment 1-5: the preparation of a kind of probiotic composition

[0044] (1) The formula of the composition

[0045] The formula of this embodiment is shown in Table 1. Production process reference figure 1 .

[0046] Table 1. Product formulation

[0047]

[0048]

[0049] Among them, sugar alcohol has an instant effect, fructooligosaccharides belong to prebiotics, which can proliferate beneficial bacteria, ascorbic acid has antioxidant function, mango fruit powder MG20, mint powder flavor TR63655E, mango powder flavor TR63490E, L-malic acid, N , 2,3-trimethyl-2-isopropylbutanamide, mint powder SD1019, and natural menthol are used to adjust the flavor.

[0050] (2) Preparation of raw materials and packaging materials: the qualified maltitol, isomalt, mango fruit powder, fructooligosaccharides, Lactobacillus plantarum R1012, xylitol, Lactobacillus rhamnosus R0011, saliva milk Bacillus HA-118, mango powder essence, Bifidobacterium animalis B94, Lactobacillus...

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Abstract

The invention discloses a probiotic composition. The probiotic composition is prepared from the following raw materials according to the dosage ratio: 50-150 * 10 < 10 > cfu of lactobacillus plantarum, 20-60 * 10 < 10 > cfu of lactobacillus rhamnosus, 10-20 * 10 < 10 > cfu of bifidobacterium animalis, 4-12 * 10 < 10 > cfu of bifidobacterium longum, 15-30 * 10 < 10 > cfu of lactobacillus helveticus, 8-20 * 10 < 10 > cfu of lactobacillus salivarius and 50-150 g of a pharmaceutical auxiliary material. The pharmaceutical auxiliary material comprises the following components in parts by weight: 0.3-0.7 parts of an antioxidant, 30-70 parts of sugar alcohol, 10-20 parts of prebiotics and 10-30 parts of a flavoring agent. The probiotic composition has an antagonistic effect on oral streptococcus mutans and can be used for treating decayed teeth or slowing down decay of teeth.

Description

technical field [0001] The invention belongs to the field of medicine, and relates to a probiotic composition and a preparation method thereof, in particular to an oral probiotic composition and a preparation method thereof. Background technique [0002] Each person has a unique flora, and the flora of the same part of the body can vary greatly from person to person. Each adult has 30 trillion cells of its own body and 40 trillion cells of gut bacteria. [0003] The oral cavity is the second largest microbial colony habitat after the gut. The oral cavity, which is completely connected to the air, also has a large number of anaerobic bacteria. Oral flora can change the balance between local and systemic health and disease; there are bacteria, fungi, archaea, protozoa and viruses in the oral cavity, and the interaction between each species and the host has an impact on the health and disease of the host. There are 700+ species of microorganisms in the mouth of a healthy adu...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): C12N1/20A61K35/745A61K35/747A61P1/02A61P31/02A61P31/04C12R1/25C12R1/225C12R1/01
CPCC12N1/20A61K35/747A61K35/745A61P1/02A61P31/02A61P31/04A61K2300/00
Inventor 邱晓霞欧晓玲
Owner 深圳保时健生物工程有限公司
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