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Composition for treating prostatitis and benign prostatic hyperplasia and preparation method thereof

A technology for prostatic hyperplasia and prostatitis, applied in the field of medicine, can solve the problems of repeated attacks, long-term cure, poor effect, etc., and achieve the effects of preventing recurrence, restoring the physiological function of the gland, and urinating significantly and smoothly.

Inactive Publication Date: 2022-02-01
刘立鹏
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although clinical urology and male specialists at home and abroad have many treatment methods for prostatitis and other diseases, the effect is not good, and they are often incurable for a long time and have repeated attacks.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0021] A composition for treating prostatitis and benign prostatic hyperplasia, which consists of the following raw materials in mass ratio: 4.0 g of cefoperazone sodium and sulbactam sodium, 20 mg of edetate disodium, 300 mg of reduced glutathione for injection, lidocaine 100mg.

[0022] The preparation method comprises the following steps:

[0023] (1), cefoperazone sodium and sulbactam sodium are dissolved with an appropriate amount of 0.9% sodium chloride solution for injection, and then diluted to 5-50ml with the same solution, the molar concentration of cefoperazone sodium after dissolving is 0.2mol / L, after dissolving The molar concentration is 0.31mol / L;

[0024] (2) At 22°C, 11.1 g of disodium edetate can be dissolved in 100 mL of water, i.e. 11.1%. The concentration of this solution is 0.3mol / L, the pH of the solution is 4.7, and the concentration for injection is 0.005% to 0.1%.

[0025] (3) 1.5 g of reduced glutathione for injection is dissolved in 100 ml of 0.9%...

Embodiment 2

[0030] A composition for treating prostatitis and benign prostatic hyperplasia, consisting of the following raw materials in mass ratio: 3.0 g of cefoperazone sodium and sulbactam sodium, 15 mg of edetate disodium, 350 mg of reduced glutathione for injection, lidocaine 80mg.

[0031] The preparation method comprises the following steps:

[0032] (1), cefoperazone sodium and sulbactam sodium are dissolved with an appropriate amount of 0.9% sodium chloride solution for injection, and then diluted to 5-50ml with the same solution, the molar concentration of cefoperazone sodium after dissolving is 0.2mol / L, after dissolving The molar concentration is 0.31mol / L;

[0033] (2) At 22°C, 11.1 g of disodium edetate can be dissolved in 100 mL of water, i.e. 11.1%. The concentration of this solution is 0.3mol / L, the pH of the solution is 4.7, and the concentration for injection is 0.005% to 0.1%.

[0034] (3) 1.5 g of reduced glutathione for injection is dissolved in 100 ml of 0.9% sodi...

Embodiment 3

[0039] A composition for treating prostatitis and benign prostatic hyperplasia, which consists of the following raw materials in mass ratio: 6.0 g of cefoperazone sodium and sulbactam sodium, 30 mg of edetate disodium, 400 mg of reduced glutathione for injection, lidocaine 140mg.

[0040] The preparation method comprises the following steps:

[0041] (1), cefoperazone sodium and sulbactam sodium are dissolved with an appropriate amount of 0.9% sodium chloride solution for injection, and then diluted to 5-50ml with the same solution, the molar concentration of cefoperazone sodium after dissolving is 0.2mol / L, after dissolving The molar concentration is 0.31mol / L;

[0042] (2) At 22°C, 11.1 g of disodium edetate can be dissolved in 100 mL of water, i.e. 11.1%. The concentration of this solution is 0.3mol / L, the pH of the solution is 4.7, and the concentration for injection is 0.005% to 0.1%.

[0043] (3) 1.5 g of reduced glutathione for injection is dissolved in 100 ml of 0.9%...

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Abstract

The invention relates to a composition for treating prostatitis and benign prostatic hyperplasia and a preparation method thereof. The composition is prepared from the following raw materials in mass ratio: 1.0-8.0 g of cefoperazone sodium sulbactam sodium, 2-40 mg of edetate disodium, 100-600 mg of reduced glutathione for injection and 20-200 mg of lidocaine. Compared with a conventional oral administration, intramuscular injection or intravenous drip medicine treatment method, the composition prepared by the method has the following advantages: the medicine directly acts on an infected part, and the lasting time of the medicine effect is long; the treatment process is easy, an operation is not needed, tissues are not damaged, a patient has no obvious pain, and the patient can freely move after being treated; various adverse reactions such as serious dysfunction of flora in the body of a patient caused by long-term oral administration, intramuscular injection or intravenous drip of antibacterial drugs are avoided.

Description

technical field [0001] The invention relates to the technical field of medicine, in particular to a composition for treating prostatitis and benign prostatic hyperplasia and a preparation method thereof. Background technique [0002] Chronic prostatitis is a common male disease with high morbidity, intractability and long course, often accompanied by prostatic hyperplasia and prostatic stones, and may cause secondary male infertility and sexual dysfunction, which brings great pain to patients. big pain. Although domestic and foreign clinical urology and male specialists have many therapeutic methods for diseases such as prostatitis, the effect is not good, often persistent and recurrent. Therefore, the present invention provides a composition directly administered through prostate microneedle injection, which can maximize the effect of antibacterial, anti-inflammatory and alleviating prostatic fibrosis in the prostate body, and is suitable for treating various chronic prost...

Claims

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Application Information

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IPC IPC(8): A61K31/546A61K9/08A61K47/18A61P13/08A61K31/167
CPCA61K31/546A61K31/167A61K9/08A61K9/0019A61K9/0034A61K47/183A61P13/08A61K2300/00
Inventor 李江查国章
Owner 刘立鹏
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