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Traditional Chinese medicine formula for resisting animal dermatomycosis and preparation method

A technology for animal skin and fungal diseases, which is applied in skin diseases, pharmaceutical formulations, antifungal agents, etc., can solve the problems of fungal drug resistance, toxicity, and difficulty in administration, so as to reduce drug resistance, have obvious effects, and have no Toxic effects

Pending Publication Date: 2022-02-08
SICHUAN AGRI UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The antifungal drugs currently used are likely to cause difficulty in administration, are toxic, and can easily cause side effects such as drug resistance of fungi

Method used

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  • Traditional Chinese medicine formula for resisting animal dermatomycosis and preparation method
  • Traditional Chinese medicine formula for resisting animal dermatomycosis and preparation method
  • Traditional Chinese medicine formula for resisting animal dermatomycosis and preparation method

Examples

Experimental program
Comparison scheme
Effect test

Embodiment

[0022] The test instruments used in this example are as follows: microplate reader MK3 Leibo: THERMO FISHER; centrifuge Intech TG16: Changsha Intech Instrument Co., Ltd.; incubator DH3600A Tongli Xinda: Tianjin Tongli Xinda Instrument; ultrasonic oscillator ; Rotary evaporator; High pressure steam sterilizer. The test reagents used are as follows: Xtt; menadione sodium bisulfite; PBS buffer; dimethyl sulfoxide; acetone; ethanol.

[0023] In this example, a traditional Chinese medicine formula for resisting animal dermatophytosis is designed, which includes the following ingredients: Sophora flavescens, cortex of white tinea, Cortex Phellodendri, cortex of hibiscus and Fructus Cnidii.

[0024] As shown in Table 1, this example adopts the formula uniform design model of traditional Chinese medicine, adopts the formula uniform design method to design experiments, and selects 16 levels in the software uniform design 3.0 to establish 5 factors, 16 levels, and 16 experimental unrest...

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Abstract

The invention relates to the technical field of medicines for treating animal dermatomycosis, and discloses a traditional Chinese medicine formula for resisting animal dermatomycosis. The formula comprises the following components: radix sophorae flavescentis, cortex dictamni, cortex phellodendri, cortex pseudolaricis and fructus cnidii. The invention also discloses a preparation method. The formula provided by the invention has obvious effects on animal-derived trichosporonsis, Microsporum gypseum, candida albicans and the like, can achieve the purpose of treatment, basically has no toxic or side effect, and can reduce drug resistance.

Description

technical field [0001] The invention relates to the technical field of medicines for treating fungal skin diseases of animals, in particular to a traditional Chinese medicine formula for resisting fungal skin diseases of animals and a preparation method thereof. Background technique [0002] Fungal dermatosis is a zoonotic infectious disease caused by skin fungi, commonly known as "copper tinea", "bald tinea", "dermatophytosis" and "psoriasis". Animals infected with fungi have skin itching, anorexia, weight loss, and decreased immunity, resulting in increased nutrient consumption, artificial waste, increased breeding costs, and sharply reduced profits, causing large economic losses to the breeding (household) farm. It is more difficult to cure wild animals after they are infected with skin fungus, which especially affects the appearance and public image, and has a serious impact on the tourism industry. Among them, Trichosporum is one of the susceptible fungi for beef cattl...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/756A61K9/06A61K9/12A61P17/00A61P31/10
CPCA61K36/489A61K36/75A61K36/756A61K36/15A61K36/234A61K9/06A61K9/12A61P17/00A61P31/10A61K2236/333A61K2236/51A61K2300/00
Inventor 马晓平刘洁刘真古玉左之才才冬杰
Owner SICHUAN AGRI UNIV