Method for safely and stably preparing sodium alkoxide solution

Abstract

The invention belongs to the technical field of organic synthesis, and particularly relates to a method for safely and stably preparing a sodium alkoxide solution, which comprises the following steps: by taking a sodium alkoxide solution as a reaction solvent, adding metal sodium into 30% sodium methoxide or 20% sodium ethoxide, then dropwise adding corresponding alcohol, controlling the reaction temperature to be below 95 DEG C, and reacting to generate the corresponding sodium alkoxide solution. The methanol (ethanol) can be uniformly dispersed in a 30% sodium methoxide (20% sodium ethoxide) solution, heat can be removed in time, an exothermic reaction is basically avoided, the methanol (ethanol) can react with metal sodium more uniformly and mildly under the protection of a saturated sodium methoxide (sodium ethoxide) solution, and sodium methoxide (sodium ethoxide) with higher content is generated; the hydrogen release amount and the evaporation amount are milder and more stable, heat is easier to transfer and disperse, the process operation is simpler and safer, the content can be more stable, and the method is more suitable for industrial production.

Description

Technical field [0001] The present invention belongs to the field of organic synthesis, and more particularly to a method of safe and stabilizing the preparation of alcohol sodium solution. Background technique [0002] Methanol (sodium ethanol sodium) solution is very wide, medical, pesticides, dyes, bioenergy, etc. are very demand. Medicine is the raw material of vitamin B1, A and sulfadiazine, which is used for pesticide production is an organic synthetic catalyst. Sodium methoxide (sodium ethanol) in terms of oil processing industry also uses to treat edible fat and edible oil catalysts to change the fat structure. It is also used as an analytical reagent to be widely used in industries such as fragrance, pesticide production, dyes. [0003] The traditional production method of sodium methanol (sodium ethanol) has a metal sodium method and a base method, and sodium methoxide (sodium ethanol) was carried out by reacting with metallodium and sodium hydroxide and methanol, respe...

AI Technical Summary

Problems solved by technology

[0006] 1) In the early stage of the reaction, the methanol (ethanol) drop rate should not be too fast. Due to poor contact, too much heat release will cause the reaction temperature to rise, and a large amount of methanol (ethanol) will evaporate, which will easily cause overtemperature and overpressure; under overtemperature and overpressure conditions, Promoting the positive reaction, metal sodium will decompose, disperse, and stabilize. It can be heated up to 200°C, and there are potential safety hazards.

[0007] 2) In the initial stage of the reaction, the amount of hydrogen released is relatively large, uneven, difficult to control, and it is easy to cause a large flow rate of hydrogen exhaust, which poses a safety hazard

[0008] 3) The heat released in the early stage is large, and the methanol (ethanol) volatilizes greatly, which may easily cause unstable content and large deviation, which will affect product quality

[0010] Defects in the existing alkaline synthesis process: high energy consumption, continuous dehydration is required; high free alkali, limited application