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Traditional Chinese medicine composition for preventing and treating tumors and post-treatment anorexia and gastrointestinal reaction

An anorexia and composition technology, which is applied in the field of medicine, can solve problems such as extrapyramidal reactions, affect the prognosis of patients, and slow onset of effects, so as to improve the quality of life, enhance immunity, and improve effectiveness.

Active Publication Date: 2022-04-19
冯利
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0027]Although there are many ways to prevent and treat tumors and loss of appetite, stomach distension, abdominal distension and nausea and vomiting after treatment, clinically, some patients’ symptoms are still difficult to relieve. The reasons are as follows: (1) The main purpose of non-drug therapy is to cooperate with and assist drug therapy, which usually takes effect slowly and requires long-term persistence and cooperation of patients, and is seldom used alone as a treatment method in clinic; Drugs such as megestrol acetate are used to improve the appetite of patients, which may cause adverse reactions such as peripheral edema, vaginal bleeding, male erectile dysfunction, adrenal insufficiency, and even increase the risk of venous thrombosis. Serious adverse reactions will offset the benefits of increasing appetite ; Adverse reactions of domperidone are rare, including depression, anxiety, decreased libido, dry mouth, rash, headache, diarrhea, drowsiness, etc., but due to the metabolism of the intestinal wall and the first-pass effect of the liver, the oral bioavailability of domperidone is very low; Pride may cause adverse reactions such as diarrhea, abdominal pain, dry mouth, rash, fatigue and dizziness; 5-HT3 receptor antagonists often cause headache, constipation, elevated transaminases, abdominal distension and abdominal pain, and in severe cases May cause prolongation of QT interval and fatal malignant arrhythmia; Metoclopramide may cause drowsiness, irritability, fatigue, orthostatic hypotension and other adverse reactions. Long-term use of large doses may cause extrapyramidal reactions. Muscle tremors, dysphonia, ataxia, etc.; (3) Loss of appetite, stomach distension, abdominal distension, and nausea and vomiting caused by tumors and related treatments are complex problems involving multiple causes, systems, and mechanisms. It is difficult to solve the above symptoms, and the combined application of multiple drugs may increase the risk of adverse reactions, and the harm caused may far exceed the improvement of symptoms
[0028]The symptoms of loss of appetite, stomach distension, abdominal distension and nausea and vomiting caused by tumors and related treatments will not only affect the patient's body function, daily life, and mental health, but also reduce the patient's It will also affect the normal treatment of cancer, and affect the prognosis of patients, which is a major problem to be solved. At present, there is no effective prevention and treatment method with quick effect, small side effects and wide application range.

Method used

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  • Traditional Chinese medicine composition for preventing and treating tumors and post-treatment anorexia and gastrointestinal reaction
  • Traditional Chinese medicine composition for preventing and treating tumors and post-treatment anorexia and gastrointestinal reaction
  • Traditional Chinese medicine composition for preventing and treating tumors and post-treatment anorexia and gastrointestinal reaction

Examples

Experimental program
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Effect test

Embodiment 1

[0092] Example 1: Prepare a Chinese medicine composition decoction 1 for preventing and treating tumors, loss of appetite and gastrointestinal reactions after treatment

[0093] The composition comprises the following components in parts by weight: 10 parts of Codonopsis pilosula, 15 parts of Atractylodes macrocephala, 10 parts of Jiang Pinellia, 10 parts of Poria cocos, 10 parts of tangerine peel, 6 parts of grass fruit, 6 parts of clove, 10 parts of Magnolia officinalis, woody 10 parts, 10 parts fried Divine Comedy, 10 parts white tribulus, 10 parts dandelion, 10 parts Baiji, 10 parts roasted licorice

[0094] According to the prescription, take a total of 137g of Chinese herbal decoction pieces of the above twelve medicinal materials, mix them, add 1000ml of water to soak for half an hour, add all the medicinal materials to 1000ml of water and decoct for 40 minutes.

[0095] Filter the medicinal liquid obtained after decocting to obtain filtrate and filter residue, and the ...

Embodiment 2

[0097] Example 2: Prepare a Chinese medicine composition water decoction 2 for preventing and treating tumors, loss of appetite and gastrointestinal reactions after treatment

[0098] The composition comprises the following components in parts by weight: 5 parts of Codonopsis pilosula, 8 parts of Atractylodes macrocephala, 5 parts of Jiang Pinellia, 5 parts of Poria cocos, 5 parts of tangerine peel, 3 parts of grass fruit, 3 parts of clove, 5 parts of Magnolia officinalis, 5 parts, 5 parts Stir-Fried Divine Comedy, 5 parts White Tribulus, 5 parts Dandelion, 5 parts Baiji, 5 parts Roasted Licorice

[0099] According to the prescription, take a total of 69g of the Chinese herbal pieces of the above-mentioned twelve medicinal materials, add water to decoct three times after mixing. Add 700ml of water for the first time and decoct for 1 hour, add 300ml of water for the second time and decoct for 1 hour, and add 300ml of water for the third time and decoct for 0.5 hours.

[0100] ...

Embodiment 3

[0102] Example 3: Prepare a Chinese medicine composition water decoction for preventing and treating tumors, loss of appetite and gastrointestinal reactions after treatment 3

[0103] The composition comprises the following components in parts by weight: 30 parts of Codonopsis pilosula, 30 parts of Atractylodes macrocephala, 15 parts of Jiang Pinellia, 15 parts of Poria cocos, 15 parts of tangerine peel, 12 parts of grass fruit, 12 parts of clove, 15 parts of Magnolia officinalis, woody 15 parts, 20 parts fried Divine Comedy, 15 parts white tribulus, 20 parts dandelion, 15 parts Baiji, 15 parts roasted licorice

[0104] According to the prescription, take a total of 244g of Chinese herbal decoction pieces of the above twelve medicinal materials, mix them, add 2000ml of water to soak for half an hour, add 2000ml of water to all the medicinal materials and decoct for 40 minutes.

[0105] Filter the medicinal liquid obtained after decocting to obtain filtrate and filter residue, ...

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Abstract

The invention belongs to the technical field of medicines, and particularly relates to a traditional Chinese medicine composition for preventing and treating tumors and post-treatment anorexia and gastrointestinal reaction. The traditional Chinese medicine composition comprises the following components in parts by weight: 5-30 parts of codonopsis pilosula, 6-30 parts of bighead atractylodes rhizome, 3-15 parts of ginger processed pinellia, 5-15 parts of poria cocos, 3-15 parts of pericarpium citri reticulatae, 3-12 parts of amomum tsao-ko, 1-12 parts of clove, 2-15 parts of mangnolia officinalis, 3-15 parts of elecampane, 4-20 parts of fried medicated leaven, 2-15 parts of tribulus terrestris, 3-20 parts of dandelion and 2-15 parts of rhizoma bletillae. The traditional Chinese medicine composition disclosed by the invention has the effects of invigorating spleen and reinforcing stomach, regulating qi and regulating middle warmer, dissolving turbidity and detoxifying, drying dampness and reducing phlegm, and resisting cancer and removing stasis, and clinical application shows that the traditional Chinese medicine composition can prevent and treat tumors and anorexia, gasteremphraxis, abdominal distension and nausea and vomiting after related treatment, relieve symptoms, relieve adverse reactions of operations, chemoradiotherapy, targeting and immunotherapy, and has a good clinical application prospect. Clinical symptoms are improved, the clinical benefit rate and life quality of cancer patients are improved, the lifetime is prolonged, and rehabilitation is promoted.

Description

technical field [0001] The invention belongs to the technical field of medicines, and in particular relates to a traditional Chinese medicine composition for preventing and treating tumors, loss of appetite and gastrointestinal reactions after treatment, and also relates to a preparation method of the composition. Background technique [0002] Malignant tumors are a global problem that seriously threatens human life and health. According to statistics, there will be about 19.3 million new cancer cases worldwide in 2020, and about 10 million deaths. It is estimated that by 2040, the number of new cancer cases worldwide will increase by 47% %. Cancer is the first or second leading cause of death among people aged <70 years in 112 countries around the world. With people's increasing attention, the widespread popularization of high-risk screening, and the continuous development of medical technology, the prognosis of cancer is getting better and better, so that the quality o...

Claims

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Application Information

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IPC IPC(8): A61K36/9064A61P1/00A61P1/08A61P1/14A61P35/00
CPCA61K36/344A61K36/284A61K36/8888A61K36/076A61K36/752A61K36/9064A61K36/61A61K36/575A61K36/285A61K36/00A61K36/185A61K36/288A61K36/898A61K36/484A61P35/00A61P1/14A61P1/00A61P1/08A61K2300/00
Inventor 冯利
Owner 冯利
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