Ribose oral liquid

A ribose oral liquid and ribose technology, applied in the field of ribose oral liquid, can solve the problems of difficult recovery of contractile function after irrigation

Inactive Publication Date: 2004-11-10
江苏省苏微微生物研究有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

When the ATP content drops to 50% of the pre-ischemic level, the myocardium will produce irreversible pathological changes, and it will be difficult to recover the contractile function even after perfusion.

Method used

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  • Ribose oral liquid
  • Ribose oral liquid
  • Ribose oral liquid

Examples

Experimental program
Comparison scheme
Effect test

preparation example 1

[0132] Preparation Example 1: Preparation of D-ribose

[0133] 1. Medium preparation:

[0134] (1). Preparation of slant medium (%)

[0135] Take glucose 0.5, peptone 1.0, yeast extract 0.4, sodium chloride 0.1, agar 2.0, pH7.2.

[0136] (2) Seed medium (%)

[0137] Corn starch enzymatic sugar 2.0, corn steep liquor 1.0, dipotassium hydrogen phosphate 0.5, potassium dihydrogen phosphate 0.2, magnesium sulfate 0.1, manganese sulfate 0.005, pH 7.2.

[0138] (3) Fermentation medium (%)

[0139] Corn starch enzymatic sugar 18, corn steep liquor 0.6, ammonium sulfate 1.0, yeast powder 0.2, magnesium sulfate 0.1, manganese sulfate 0.01, calcium carbonate 2.0, pH 7.5.

[0140] (4) fermentation

[0141] Inoculate the preserved Bacillus subtitis JSIM-1018 strain with the preservation number CGMCC NO 0328 on the slant of 5 eggplant bottles, culture at 30°C for 48 hours, wash the bacterial lawn on the slant with sterile saline, and combine under aseptic conditions Put it into the s...

Embodiment 1

[0143] Embodiment 1: the preparation of D-ribose oral liquid

[0144] The product formula is:

[0145] (1) D-ribose, 35-40 kg.

[0146] (2) Distilled water, 60 liters, dilute to 100 liters with distilled water after dissolving.

[0147] The weight percentage of the relative content of D-ribose is 35-40%.

[0148] The prepared distilled water should meet the requirements for distilled water in Part Two of the Pharmacopoeia of the People's Republic of China in 2000. This product is oral liquid, the content is colorless to light yellow. The main active ingredient of ribose oral liquid is D-ribose. According to the results of the functional test, the single component of D-ribose has the declared function, and D-ribose is easy to absorb moisture, has a great solubility in water, and can be miscible with water in any ratio. More than 50% ribose solution is viscous and has poor fluidity. In order to facilitate storage and human body absorption, 35-40% D-ribose solution is used ...

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Abstract

The ribose oral liquid is water solution of D-ribose in distilled water and has D-ribose content of 35-40 wt%. The present invention is one kind of high-tech bioengineering product. Functional experiment shows that the product can prolong mouse's weight-loading swimming time and rod clamping time and reduce mouse's serum urea and glycogen consumption and has obviously anti-fatigue effect. It contains no any hormone and has no toxic side effect.

Description

technical field [0001] The invention relates to a ribose oral liquid, especially a D-ribose oral liquid. Background technique [0002] As we all know, the energy of the human body comes from food, mainly sugar, fat and protein. After the sugar is digested and absorbed, it is transported by the blood to the corresponding parts, undergoes aerobic metabolism and stores the energy produced in the high-energy compound adenosine triphosphate (ATP). ATP is the direct provider of energy for human activities, so when there is a shortage of ATP in the body, people will feel tired. The real mechanism of fatigue is that when people are engaged in physical and mental work, they consume too many nutrients including various amino acids, vitamins and trace elements. The excessive consumption of various nutrients in the body is the result of the shortage of ATP in the human body, which indicates that the nutritional environment in the body is already in an unbalanced state. If these nutri...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K31/7004A61P43/00
Inventor 柏建新邓崇亮朱晓宏
Owner 江苏省苏微微生物研究有限公司
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