Nisoldipine double layer penetrated pump control releasing tablets

A technology of osmotic pump controlled release and nisoldipine, which is applied in the fields of cardiovascular system diseases, pharmaceutical formulations, drug combinations, etc., can solve the problems of frequent taking of ordinary tablets, long-lasting drug effects, large fluctuations in blood drug concentration, etc., to achieve The effect of long-lasting drug effect, small fluctuation of blood drug concentration, and less frequency of taking medicine
CN1439372AInactive Publication Date: 2003-09-03SHENYANG PHARMA UNIVERSITY
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Patent Information

Authority / Receiving Office
CN Β· China
Patent Type
Applications(China)
Current Assignee / Owner
SHENYANG PHARMA UNIVERSITY
Publication Date
2003-09-03
Estimated Expiration
Not applicable Β· inactive patent

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Abstract

A release controllable nisoldipine with dual-layer osmotic pump for treating cardiovascular diseases including hypertension, angine pectoris, left ventricular disfunction and congestive heart failure contains nisoldipine (5-20 wt.%), polyoxyethene and / or sodium chloride and / or hydroxypropyl methylcellulose as the release controlling agent of medicine layer, polyoxyethene and / or hydroxypropyl methylcellulose and / or ethylcellulose as the release controlling agent of boosting layer, and acetate cellulose and / or ethylcellulose and / or hydroxypropyl methylcellulose and / or polyethanediol as release-controlling membrane.
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Description

Technical field:

[0001] The invention relates to a nisoldipine drug for treating hypertension, angina pectoris, left ventricular insufficiency and congestive heart failure-nisoldipine double-layer osmotic pump controlled-release tablet. Background technique:

[0002] There are many nisoldipine medicines available in the market, but the common nisoldipine tablet is taken frequently, which is inconvenient to take, the blood drug concentration fluctuates greatly, the drug effect is not durable, the curative effect is not stable enough, and there are certain toxic and side effects. Invention content:

[0003] The object of the present invention is to provide a nisoldipine double-layer osmotic pump controlled-release tablet, which has the characteristics of convenient administration, long-lasting effect, stable curative effect and less toxic and side effects.

[0004] The purpose of the present invention is achieved like this:

[0005] Preparation of the present invention cont...

Claims

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