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New slimming effervescent tablet form

An effervescent tablet and new dosage form technology, applied in the field of weight loss drug preparations, can solve the problems of inconvenience, unacceptability, inconvenience and the like

Inactive Publication Date: 2005-04-27
SICHUAN INDAL INST OF ANTIBIOTICS CHINA NAT PHARMA GROUP CORP
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, currently used dosage forms include capsules, tablets, chewing gum, etc., but all have some disadvantages: capsules are more commonly used.
Because the usual dose of calcium pyruvate is 3 to 6 grams per day, or even higher, these dosage forms have the major disadvantages of inconvenient taking and difficult acceptance by the public
We were surprised to find that making it into effervescent tablets has more advantages: (1) Although effervescent tablets are tablets in form, they quickly turn into liquid drinks when taken, and they are far more effective than those thicker ones. Ordinary tablets or capsules (due to the large dosage, it is impossible to make them very small, foreign products are as large as 750mg / capsule; if the size of each capsule is made smaller, you need to take many capsules each time, which is also inconvenient to take) convenient

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0015] Take 4.8 kg of calcium pyruvate, 1 kg of L-carnitine, 1 kg of taurine, 0.8 kg of vitamin C, 0.2 kg of stevioside, 0.2 kg of sodium chloride, 3 kg of citric acid, 3 kg of sodium bicarbonate, and 0.6 kg, 3.4 kg of lactose, and 2 kg of soluble starch, all of which are of pharmaceutical grade, were mixed and sieved according to the conventional methods of the pharmaceutical industry, and made into 10,000 tablets.

Embodiment 2

[0017] Take 6 kg of calcium pyruvate, 1 kg of L-carnitine, 1 kg of taurine, 0.8 kg of vitamin C, 0.1 kg of vitamin B2, 0.2 kg of xylitol, 0.2 kg of sodium chloride, 3 kg of malic acid, and 3 kg of sodium bicarbonate 1 kg, 0.6 kg of micro-opened starch, 4.4 kg of lactose, and 3 kg of soluble starch, all of which are of pharmaceutical grade, were mixed and sieved according to the conventional methods of the pharmaceutical industry, and made into 10,000 tablets.

Embodiment 3

[0019] Take 3 kg of calcium pyruvate, 0.5 kg of L-carnitine, 0.5 kg of taurine, 0.8 kg of vitamin C, 0.1 kg of vitamin B2, 0.2 kg of aspartose, 0.2 kg of sodium chloride, 3 kg of citric acid, and sodium bicarbonate 3 kg, 1 kg of sodium carboxymethyl starch, 3.4 kg of S630, 2 kg of soluble starch, all of which are of pharmaceutical grade, mixed and sieved according to the conventional methods of the pharmaceutical industry, and made into 10,000 tablets.

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PUM

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Abstract

The new slimming effervescent tablet form consists of calcium pyruvate as active component, swelling agent, corrective, acid providing hydrogen ion and common medicinal supplementary material. It has convenience in carrying about and taking, fast absorption, excellent compatibility and easy-to-regulate dosage, and can well promote fat metabolism, slimming, improve bodily form, and prevent and treat obesity related disease.

Description

technical field [0001] The invention relates to the field of weight-loss pharmaceutical preparations, in particular to an effervescent tablet dosage form with calcium pyruvate as the main active ingredient and supplemented with L-carnitine, taurine, vitamins and other ingredients that have health care effects on human body. Background technique [0002] As we all know, obesity has become a disease of civilization in modern society, and it is listed as the four major medical and social problems in the world together with AIDS, drug abuse and alcoholism. The medical profession has called the hypertension, diabetes, coronary heart disease, and stroke often accompanied by obesity "the death quintet". This terrible quintet is the number one killer of human health and life in the 21st century, which significantly increases the fatality rate. Statistics show that if the standard mortality rate is 100%, the mortality rate of those who are 25% overweight increases to 128%, and the m...

Claims

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Application Information

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IPC IPC(8): A61K9/20A61K9/46A61K31/19A61P3/04
Inventor 杨放周善学姚洁
Owner SICHUAN INDAL INST OF ANTIBIOTICS CHINA NAT PHARMA GROUP CORP
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