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Powdery wound paste with instant soluble seal and production thereof

A wound patch and powder technology, which is applied in the field of pharmaceutical preparations, can solve the problems of difficult ventilation, aggravated infection, poor ventilation performance, etc., and achieves the effects of good coagulation effect, rapid hemostasis, and convenient carrying.

Inactive Publication Date: 2005-10-12
NORTHWEST UNIV(CN)
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the traditional Band-Aid itself has some shortcomings that cannot be ignored: when the Band-Aid is applied to the skin wound, because of its poor air permeability, when the application time is long, the moisture evaporation of the wound skin will be affected, thereby affecting the normal respiratory function of the skin and Physiological function weakens the surface cell regeneration ability of the wound skin and prolongs the wound healing time (Liu Tangxia, Disadvantages of long-term application of band-aids on wounds, Qilu Nursing Magazine, 1996, 2 (4): 24); also because it is not easy to breathe, If used in hot seasons, it is easy to have ulceration and pus. If the use is not stopped in time, the infection will be aggravated (Chen Yumin, Band-aid is not a panacea, Changshou, 1996, August, 21.)
But it ignores the advantages of traditional Chinese medicine powder medicine in the treatment of external trauma, which is not conducive to the healing of wound surface

Method used

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  • Powdery wound paste with instant soluble seal and production thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0025] (A) Preparation of instant drug film containing medicinal therapeutic ingredients. Take 50g of Baiji, crush it into a coarse powder, add 4 times of water to soak for 12 hours, then add 20 times of water, reflux at 60°C for 4 hours, and pump liquid A; add 20 times of water to the filter residue, and reflux at 90°C for 4 hours to obtain the filtrate B; combine A and B to obtain Baijijiao. Measure 150ml of the prepared Baiji glue, stir it evenly with a magnetic stirrer, centrifuge at 3000 rpm / centrifuge, take the supernatant glue solution, add 4ml glycerol, drop 2 drops of azone, and apply it evenly on the glass with a glass rod Dry on the board at room temperature to form a drug film with a thickness of about 0.3 mm.

[0026] (B) if figure 1 As shown, get 0.5g hemostatic callus powder (4), such as Yunnan Baiyao, wrap with the above-mentioned instant film (5) of 2 * 4cm size, do not cause the powder to spill.

[0027] (C) Paste the encapsulated small medicine package on...

Embodiment 2

[0029] (A) Preparation of instant drug film. Get model is 10 grams of polyvinyl alcohol of 17-88, sodium carboxymethyl cellulose 5 grams, H 2 O 400 g, magnetically stirred at 80°C to form a homogeneous solution. Spread evenly on a glass plate with a glass rod, and let it dry at room temperature to form a drug film.

[0030] (B) Take 0.5g of Panax notoginseng powder, place it in an instant film of a suitable size, such as 2×4cm, and wrap it with the instant film to prevent the powder from spilling out.

[0031] (C) Paste the encapsulated small medicine bag gently on the backing in the center of the self-adhesive adhesive tape with suitable pressure. finished product.

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Abstract

An adhesive bandage with powder medicine packed by instant film is composed of a substrate, the staltic and wound treating powder medicine, and the instant film made of non-toxic high-molecular material or the natural high-molecular material extracted from Chinese-medicinal materials, such as bletilla gum, aloe gel, aloe polyose, konjak gel, konjak polyose, etc.

Description

technical field [0001] The invention belongs to the field of pharmaceutical preparations, in particular to a pharmaceutical preparation in the form of a patch. Background technique [0002] Traditional Chinese medicines for knife wounds are powders, such as the famous Yunnan Baiyao. The use of powder to treat knife wounds and small wounds in daily life has great advantages. After thousands of years of clinical verification, Chinese medicine powder has a rapid hemostatic effect; It coagulates, ruptures and releases blood coagulation factors for the core, and quickly achieves the effect of hemostasis. The powder trauma medicine powder has the advantages of ventilation, stopping exudation and accelerating wound healing when used in wounds. [0003] However, the use of powder medicine also has certain inconveniences. For example, when the patient uses it, it is difficult to control the medicine each time, and it does not meet the quantitative requirements; it is extremely incon...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/70A61P7/04A61P17/00
Inventor 郝保华刘建利徐花荣
Owner NORTHWEST UNIV(CN)
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