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Huoliguan dripping pill for tonifying heart and kidney and its preparing method

A vitality and coronary heart disease technology, applied in the direction of medical preparations containing active ingredients, pill delivery, pharmaceutical formulations, etc., can solve the problems of inconvenient taking or carrying, low dissolution rate, low drug content, etc., to improve bioavailability , faster dissolution and absorption, and a high degree of automation

Inactive Publication Date: 2005-10-19
北京博智绿洲医药科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] Due to the preparation technology and other reasons, the oral preparations of most drugs, especially the oral preparations of traditional Chinese medicine, have problems such as long dissolution time, low dissolution rate, poor absorption, hepatic and intestinal first-pass effect and low bioavailability after taking. , thus affecting the efficacy of the drug and directly affecting the therapeutic effect
However, syrup oral preparations also have disadvantages such as low drug content, difficulty in taking and measuring accurately, inconvenient taking or carrying, etc.
[0008] In addition, conventional oral dosage forms, such as tablets, capsules, etc., will produce relatively large dust pollution due to the granulation process in the preparation process, which will cause harm to the health of the staff to a certain extent, and will also cause harm to the human body. some pollution to the environment
Furthermore, the production process of conventional oral preparations is complicated and the production cost is high, so that the cost of medication for patients is also increased, which is not conducive to improving the ability of patients to seek medical treatment, and is also not conducive to improving the overall health level of society.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0031] Now with several groups of specific examples, the preparation method of the active source dropping pills of the present invention will be further described.

[0032] Group 1: Tests with a single matrix

[0033] 1. Preparation of medicinal extracts: According to the [Appendix], the dry powder containing active ingredient extracts of ginseng stems and leaves, astragalus, Schisandra chinensis, Ophiopogon japonicus, and Fupian active ingredients was first prepared for use;

[0034] 2. Substrate: polyethylene glycol (1000、2000、4000、6000、8000、10000、20000) , polyoxyl 40 stearate, beta cyclodextrin, poloxamer, sodium carboxymethyl starch, sodium lauryl sulfate, stearic acid, sodium stearate, glycerin gelatin, shellac;

[0035] 3. Proportion: take g or kg as the unit, by weight, drug extract: matrix = 1:1~1:9;

[0036] 4. Prepare according to the process given in [Preparation Method] 4-7, and you can get different specifications of Qigongyuan Dropping Pills.

[0037] [test re...

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PUM

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Abstract

The present invention relates to a kind of medicine composition, vitality source dripping pill, for treating insomnia, hypomnesis, coronary heart disease, chronic hepatitis, diabetes, climacteric syndrome, etc. caused by vital energy and yin deficiency and heart and kidney deficiency. The present invention has high bioavailability, fast medicine release, fast acting, high effective content, taking convenience and low cost. The vitality source dripping pill is prepared with four kinds of Chinese medicinal materials of astragalus root, schisandra, ophiopogon root, aconite root and medicine carrier as matrix.

Description

technical field [0001] The present invention relates to a medicine that has the effects of nourishing qi and nourishing yin, strengthening the heart and kidney, and is used for the treatment of diseases such as amnesia, insomnia, hypomnesis, coronary heart disease, chronic hepatitis, diabetes and menopausal syndrome caused by deficiency of both qi and yin and deficiency of both heart and kidney. The pharmaceutical composition particularly relates to an oral preparation of a pharmaceutical composition prepared from extracts containing total saponins of stems and leaves of ginseng and extracts of active pharmaceutical components of four traditional Chinese medicines such as astragalus, schisandra, Radix Ophiopogon japonicus and Fupian. Background technique [0002] Guiqishen Oral Liquid, which is prepared according to the preparation method given in the ministerial drug standard WS3-B-3277-98, is a kind of tonifying qi and nourishing yin, strengthening the heart and nourishing ...

Claims

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Application Information

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IPC IPC(8): A61K9/20A61P1/16A61P3/10A61P9/10A61P15/12A61P31/14
Inventor 曲韵智
Owner 北京博智绿洲医药科技有限公司