Method for detecting anti-liver cancer efficacy of tyroserleutide, kit and gene chip used thereby

A gene chip, anti-cancer technology, applied in biochemical equipment and methods, microbial determination/examination, DNA/RNA fragments, etc., can solve problems such as unpredictability of patients
CN1837374AInactive Publication Date: 2006-09-27SHENZHEN KANGZHE PHARM CO LTD
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
SHENZHEN KANGZHE PHARM CO LTD
Publication Date
2006-09-27
Estimated Expiration
Not applicable · inactive patent

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Abstract

The invention discloses a detecting method and its agent box and gene chip of tyr-ser-leu protein anti-hepatocarcinoma effect, which comprises the following steps: detecting the changing condidtions of gene NDUFA2, NDUFA10, NDUFS1, SUCLG1, Calreticulin, PTEN, Akt1, Akt2, P21and P27 expression level in the biological material after acted by tyr-ser-leu protein; displaying downward for gene NDUFA2, NDUFA10,NDUFS1,SUCLG1,Akt1,Akt2 and upward for the expression level of gene Calreticulin,PTEN, P21,P27; possessing anti-hepatocarcinoma effect. The invention provides a rapid detecting path of tyr-ser-leu protein anti-hepatocarcinoma effect on the molecular level.
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Description

technical field

[0001] The invention relates to a method and a preparation for detecting the anticancer effect of drugs, in particular to a method for detecting the anticancer effect of tyroserleutide at the molecular level, a kit and a gene chip used therefor. Background technique

[0002] Primary liver cancer is one of the most common malignant tumors of the digestive tract in humans. Its incidence rate ranks eighth among major cancers in the world, and its mortality rate is high. It is second only to gastric cancer and esophageal cancer in the mortality rate of malignant tumors and ranks third. . China is a country with a high incidence of primary liver cancer. Its morbidity and mortality rates rank first in the world, and its mortality rate ranks second among various cancers. About 110,000 people die from liver cancer every year, accounting for about 100,000 deaths from liver cancer in the world. about 45%. Currently, surgery, radiotherapy and chemotherapy are the main...

Claims

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