Immuo-colloidal gold test paper for detecting pyloric helicobacter antigen and its prepn process

A Helicobacter pylori, colloidal gold test paper technology, applied in the direction of measuring devices, instruments, scientific instruments, etc., can solve other bacteria such as Campylobacter Bacteria are also found, false positives and other problems
CN1847854AInactive Publication Date: 2006-10-18LANZHOU UNIVERSITY
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Patent Information

Authority / Receiving Office
CN ยท China
Patent Type
Applications(China)
Current Assignee / Owner
LANZHOU UNIVERSITY
Publication Date
2006-10-18
Estimated Expiration
Not applicable ยท inactive patent

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Abstract

The present invention relates to one kind of immuno-colloidal gold test paper for detecting pyloric helicobacter antigen and its preparation process. The test paper has coated urease monoclonal antibody, CagA or VacA monoclonal antibody and anti-mouse polyclonal antibody. It is used in detecting pyloric helicobacter related antigen existing in saliva, gastric juice, vomited matter, dental plaque and excrement of mammal so as to monitor the infection status of pyloric helicobacter, assist the diagnosis of gastritis, peptic ulcer and other diseases and predict gastric cancer probability. The present invention simple operation, high specificity and high sensitivity.
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Description

technical field

[0001] The invention relates to an immune colloidal gold reagent for detecting antigens and a detection method thereof, and also relates to a preparation method of the reagent. Background technique

[0002] Helicobacter pylori (Helicobacter pylori, Hp) has a chronic infection rate of more than 50% in the population of the world, and the infection rate of the general population in my country is about 50%-80%, and it is still at an annual rate of 1%-2%. Increase. Hp is the main pathogenic factor of type B gastritis, peptic ulcer and gastric mucosa-associated lymphoid tissue lymphoma, and is closely related to the occurrence of gastric cancer. It has been listed as the first-class biological carcinogen by WTO. It can also cause other diseases such as: coronary heart disease angina pectoris, growth retardation or indigestion in children, urticaria, immune platelet purpura, hepatic coma, symptomatic hypoglycemia, high blood pressure, and gallstones.

[0003] Epid...

Claims

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