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Improved Chinese medicinal capsule for treating climacteric syndrome

A technology for traditional Chinese medicine capsules and syndromes, which is applied in the directions of capsule delivery, drug combination, and pharmaceutical formulations, can solve problems such as poor extraction effect, decreased capsule efficacy and stability, and achieve the effect of overcoming poor extraction effect.

Inactive Publication Date: 2006-12-13
SUNSTONE TANGSHAN PHARM CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] According to the improved traditional Chinese medicine capsule for the treatment of climacteric syndrome provided by the present invention, it overcomes the poor extraction effect of the volatile oil and other active ingredients of medicinal materials in the existing technology, and the decline of capsule efficacy and stability due to the presence of volatile oil. defect

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0084] The improved Chinese medicine capsule for treating women's menopausal syndrome is made of main medicine components and capsule auxiliary materials.

[0085] The main ingredients include ginseng, wolfberry, angelica, rehmannia, red peony root, dogwood, anemarrhena, cork, paeonol, calamus, polygala, tuckahoe, dodder, epimedium, morinda, cnidii, dog ridge, Schisandra.

[0086] Based on every thousand capsules, the preferred dosage of each component of the Chinese medicine capsule is:

[0087] Ginseng 40.5g, Chinese wolfberry 54.1g, Angelica 54.1g, Rehmannia 54.1g, Red peony 54.1g, Dogwood 54.1g, Zhimu 40.5g, Cork 54.1g, Paeonol 54.1g, Shichangpu 27g, Polygala 40.5g, Poria 54.1 g. Cuscuta seed 81g, Epimedium 81g, Morinda officinalis 81g, Cnidium monnieri 54.1g, Gouji 54.1g, Schisandra 40.5g.

[0088] Preferably, the volatile oils extracted from Angelica sinensis, Shichangpu, Schisandra, Cnidium, and Moutan bark are clathrated with β-cyclodextrin to prepare inclusion compound po...

Embodiment 2

[0090] The improved traditional Chinese medicine capsule for treating women's menopausal syndrome as in Example 1, but the main medicine components are prepared by the following method:

[0091] 1. Take ginseng and tuckahoe into fine powder, pass through a 100-mesh sieve for later use.

[0092] 2. Take Angelica sinensis, Shichangpu, Schisandra, Cnidium vulgare, and Moutan bark, add water to extract the volatile oil, filter the residue after distillation, and collect the filtrate and filter residue respectively.

[0093] The extracted volatile oil is clathrated with β-cyclodextrin to prepare clathrate powder for use.

[0094] 3. Take Cuscuta, Morinda officinalis, Cornus officinalis, Epimedium, Anemarrhena, and the filter residue of the volatile oil extracted in step 2, extract with ethanol, and filter the alcohol extract; collect the filtrate and the alcohol extraction residue respectively.

[0095] The filtrate is concentrated to form an alcohol extract concentrate.

[0096] 4. Ta...

Embodiment 3

[0099] The improved traditional Chinese medicine capsule for treating women's menopausal syndrome as in Example 1 or 2, but the capsule auxiliary materials include binders, fillers, disintegrants, hygroscopic agents, lubricants and the like.

[0100] The binder can be selected from any one of 95% ethanol, polyvinylpyrrolidone, polyvinylpyrrolidone / vinyl acetate copolymer, etc.;

[0101] The filler may be selected from any one of starch, lactose and the like.

[0102] The disintegrant can be selected from any one of sodium carboxymethyl starch, low-substituted hydroxypropyl cellulose, cross-linked polyvinylpyrrolidone and the like.

[0103] Micronized silica gel can be used as the hygroscopic agent.

[0104] The lubricant can be micro-powder silica gel.

[0105] The main drug components are added with capsule auxiliary materials, granulated with 95% ethanol, dried, and filled into capsules.

[0106] Preferably, 20% calcium carbonate is mixed with an appropriate amount of starch, gr...

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PUM

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Abstract

Disclosed is a Chinese medicinal capsule for treating women's climacteric metancholia comprising main medicament compositions and capsule auxiliary materials. The main medicament compositions include gen-seng, wolferry fruit, Chinese angelica root, prepared rhizome of rehmannia, radix paeoniae rubrathe, cornus officinalis, anemarrhena rhizome, corktree bark, root bark of tree peony, grassleaved sweetflag rhizome, polygala root, poria cocos, dodder seed, epimeddium, morinda root, cnidium fruit, east Asian tree fern rhizome and schisandra fruit, and the capsule auxiliary materials include binding agent, bulking agent, crumbling agent, desiccating agent and lubricating agent.

Description

Technical field [0001] The invention relates to a traditional Chinese medicine capsule for treating women's menopausal syndrome, in particular to an improved traditional Chinese medicine capsule for treating women's menopausal syndrome. Background technique [0002] Menopausal syndrome is a common disease in middle-aged and elderly women. It means that some women have symptoms related to menopause before and after menopause. Visible dizziness, tinnitus, hot sweating, palpitations, insomnia, irritability, or chills, cold limbs, fatigue, menstruation before or after, more or less or twice a month or stop, vaginal dryness, Low libido, or mental depression, the severity of the syndrome, and the duration varies. The shortest one is a year or a half, and the elderly stay for several years, which often affects life and work. This disease is caused by insufficient yin and yang, deficiency of kidney qi, insufficient qi and blood before and after menopause. Patients may be in tension and i...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8964A61K9/48A61P15/12
Inventor 韩志强贾晓冬
Owner SUNSTONE TANGSHAN PHARM CO LTD
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