Wound treatment employing reduced pressure

a wound treatment and pressure reduction technology, applied in the field of wound treatment using reduced pressure, can solve the problems of large or infected wounds, inability to spontaneously close, wounds that cannot successfully fight bacterial infections, etc., to promote epithelial migration, reduce pressure, and enhance the attachment of adjacent tissu

Inactive Publication Date: 2006-09-28
ARGENTA LOUIS C +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Benefits of technology

[0015] Another aspect of the invention is a method of enhancing the attachment of adjacent tissue to a wound which comprises applying negative or reduced pressure to a joined complex of the adjacent living tissue and the wound at a sufficient magnitude of reduced pressure and for a

Problems solved by technology

The treatment of open wounds that are too large to spontaneously close has long been a troublesome area of medical practice.
Some wounds, however, are sufficiently large or infected that they are unable to heal spontaneously.
Without sufficient blood flow, the wound is unable to successfully fight bacterial infection and is accordingly unable to close spontaneously.
Infection and poor vascularization hinder the formation of granulation tissue within wounded tissue, thereby inhibiting wound healing.
Poor blood circulation and infection at the wound may also hinder attachment of skin grafts or flaps upon wounded tissue.
Another problem encountered during the treatment of wounds is the selection of an appropriate technique for wound closure during the healing process.
However, sutures apply a closure force to only a very small percentage of the area surrounding a wound.
When there is scarring, edema, or insufficient tissue, the tension produced by the sutures can become great causing excessive pressure to be exerted by the sutures upon the tissue adjacent to each suture.
As a result, the adjacent tissue often becomes ischemic thereby rendering suturing of large wounds counterproductive.
If the quantity or size of the sutures is increased

Method used

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  • Wound treatment employing reduced pressure

Examples

Experimental program
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Effect test

example 1

Treatment of Open Wounds

[0053] In order to demonstrate the use of a negative pressure appliance in the treatment of open wounds, an animal study was conducted using pigs as subjects. Pigs are frequently used as subjects in wound healing studies since they have essentially the same skin and subcutaneous tissue structure as humans.

[0054] Five 15 kg Chester pigs were obtained and acclimated for 1 week prior to use. The animals were sedated with an intramuscular injection of ketamine (25 mg / kg): xylazine (2.5 mg / kg): acepromazine (5 mg / kg). The backs and sides of the animals were shaved and scrubbed for surgery. One percent halothane was administered by endotracheal tube for maintenance of anesthesia. Two circular wounds were created on the midline of the animals. The wounds were 2.5 cm in diameter having a depth reaching, but not including, the deep fascia over the spine (approximately 1 cm). Wounds in pigs in this site do not contract during healing. Alginate impressions were made o...

example 2

Reduction of Infection

[0057] During the course of the experiment described as Example 1 above, it was observed that the reduced pressure-treated wounds were much cleaner and bled more spontaneously than non-treated wounds. It was therefore undertaken to determine the relative rates of clearance of a known bacterial inoculum from treated and non-treated wounds.

[0058] Five 15 kg pigs were obtained and wounds created as set forth in Example 1. Two 2.5 cm diameter defects were created on the dorsum of each pig using a sterile technique, with a 7.5 cm interval retained between the edges of the defects. Hemostasis was obtained by electrocautery. Prior to placement of the reduced pressure appliances, 108 organisms of Staphylococcus aureus in 1 ml saline solution were injected into each wound. The reduced pressure appliances of the type shown in FIGS. 2 and 11 were then attached as in Example 1. A reduced pressure of 5 in. Hg below atmospheric pressure was applied to one of the wounds upo...

example 3

Treatment of Burns

[0061] Use of reduced pressure appliances upon burns has been found to retard the progression of partial thickness burns into full thickness burns. A partial thickness burn is a burn in which the depth of cell death due to thermal trauma does not extend below the level of the deepest epidermal structures (i.e., the base of hair follicles, sweat glands, sebaceous glands, etc.). A burn that is initially a partial thickness burn will often deepen and progress into a full thickness burn due to insufficient blood circulation to the epidermal cells beneath the partial burn.

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Abstract

A method of treating tissue damage comprises applying a negative pressure to a wound sufficient in time and magnitude to promote tissue migration and thus facilitate closure of the wound. The method is applicable to wounds, burns, infected wounds, and live tissue attachments. A wound treatment apparatus is provided in which a fluid impermeable wound cover is sealed over a wound site. A screen in the form of an open-cell foam screen or a rigid porous screen is placed beneath the wound cover over the wound. A vacuum pump supplies suction within the wound cover over the treatment site.

Description

FIELD OF THE INVENTION [0001] The present invention relates to an apparatus and method for treating a wound by applying reduced pressure to the wound. BACKGROUND OF THE INVENTION [0002] The treatment of open wounds that are too large to spontaneously close has long been a troublesome area of medical practice. Closure of an open wound requires inward migration of surrounding epithelial and subcutaneous tissue. Some wounds, however, are sufficiently large or infected that they are unable to heal spontaneously. In such instances, a zone of stasis in which localized edema restricts the flow of blood to the epithelial and subcutaneous tissue forms near the surface of the wound. Without sufficient blood flow, the wound is unable to successfully fight bacterial infection and is accordingly unable to close spontaneously. [0003] An initial stage of wound healing is characterized by the formation of granulation tissue which is a matrix of collagen, fibronectin, and hyaluronic acid carrying ma...

Claims

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Application Information

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IPC IPC(8): A61B19/00A61B17/00A61B17/08A61B17/30A61F13/00A61F13/02A61M1/00A61M1/08A61M16/06A61M27/00
CPCA61B17/08A61B17/085A61B19/00A61B2017/00557A61B2017/306A61F13/02A61F2013/00919A61M1/0023A61M1/0037A61M1/0056A61M1/008A61M1/0088A61M1/08A61M16/06A61M27/00A61M2205/3379A61M1/005A61F13/00068A61B90/00A61F13/0226A61F13/0246A61M2205/7518A61M2205/7545A61M1/75A61M1/782A61M1/79A61M1/84A61M1/91A61M1/982
Inventor ARGENTA, LOUIS C.MORYKWAS, MICHAEL J.
Owner ARGENTA LOUIS C
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