The invention discloses a craniofacial bone malformation reduction surgery system based on mutual collaboration of main and auxiliary robots. The craniofacial bone malformation reduction surgery system comprises mechanical arms, a craniofacial bone-cutting milling cutter device, a bone flap grabbing device, a ventriculoscope detecting device, AR glasses used for wearing of clinicians, a computer,a display screen, a control system and a locating marker, wherein the mechanical arms comprise a main mechanical arm and an auxiliary mechanical arm, the ventriculoscope detecting device is mounted onthe craniofacial bone-cutting milling cutter device, and the craniofacial bone-cutting milling cutter device is mounted at the tail end of the main mechanical arm; the bone flap grabbing device is mounted at the tail end of the auxiliary mechanical arm. For the craniofacial bone malformation reduction surgery system based on mutual collaboration of the main and auxiliary robots and a surgery operation method adopted by the system, the superposition of a three-dimensional operation plan and the neurocranium of a pediatric patient is realized, meanwhile, automatic tracking and navigational positioning are realized, the main and auxiliary robots realize mutual collaboration, the surgery operation is realized, and a doctor can intervene the operation at the right time.