The invention discloses handheld dust collection equipment and a power supply 
layout structure. The equipment comprises a dust cylinder 
assembly, an air outlet cylinder, a dust collection part, a handheld part, a supporting reinforcing part and a 
power module. The upper end of the handheld part is connected to the air outlet cylinder, the supporting reinforcing part is connected between the lowerend of the handheld part and the air outlet cylinder to define a holding hollow area, and the 
power module and the supporting reinforcing part enable the 
power module to be installed on the outer sideof the supporting reinforcing part through a 
locking mechanism. An electric connecting end 
assembly is arranged on the contact surface between the power supply module and the supporting reinforcing part, so that the power supply module can provide 
electric energy for the operation of the dust collection part; due to the arrangement mode, the whole dust collection equipment is compact in structureand reasonable in 
gravity center distribution; the external power supply module enables a user to dismount and 
mount the power supply module in a more time-saving, labor-saving, rapid and convenientmanner, and meanwhile, the connecting force after the power supply module is mounted is concentrated on the 
locking mechanism, so that the electric connecting end 
assembly is prevented from being deformed and damaged due to stress, and the problem of poor contact is avoided.