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Service system and method by using technique of gene detection to provide active health service

A detection service and health technology, applied in the fields of molecular biology and medicine, can solve problems such as discomfort, decreased ability to metabolize acetaldehyde, alcoholism, etc.

Inactive Publication Date: 2007-12-26
XINBAXIANG SHANGHAI MOLECULAR MEDICAL TECH SHANGHAI
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In contrast, the risk of Alzheimer's disease among people who tested negative for the e4 allele of the APOE gene was less than 10%.
The rs671 polymorphic change (G / A) defect of the ALDH2 gene leads to a decrease in the body's ability to metabolize acetaldehyde, causing discomfort in drinking, flushing syndrome, etc., and easily leading to alcoholism

Method used

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  • Service system and method by using technique of gene detection to provide active health service
  • Service system and method by using technique of gene detection to provide active health service
  • Service system and method by using technique of gene detection to provide active health service

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0044] Example 1. Active Health Service Series I-Single Service for Coronary Heart Disease Prevention

[0045] Step 1: Sampling

[0046] The subjects were consulted before the service, and the subjects signed the informed consent and filled out the questionnaire on living and eating habits. According to the instructions in the sampling box, use oral swabs to sample oral epithelial cells, transport the samples to the testing center, and enter the information barcode management process.

[0047] Step 2: Genotyping Assay Processing

[0048] The DNA extraction of oral epithelial cells was carried out by silica gel adsorption method (patent application number 200610023818.0). The target fragment of the coronary heart disease-related gene PON1 is located for specific PCR amplification, and after amplification, the PON1 genotyping test is performed using the conventional genotyping method, and the PON1 genotyping test result is obtained.

[0049] Step 3: Active Health Services

...

Embodiment 2

[0051] Example 2. Active Health Service Series II - Special Service for Tobacco and Alcohol Injury Assessment

[0052] Step 1: Sampling

[0053] The subjects were consulted before the service, and the subjects signed the informed consent and filled out the smoking and drinking habit questionnaire. The sampling process is the same as in Example 1.

[0054] Step 2: Genotyping Assay Processing

[0055]The DNA extraction process was the same as in Example 1. To locate tobacco and alcohol damage-related genes (genes related to tobacco and alcohol damage can be found through the National Biological Gene Detection Technology Application Evaluation and Certification Center of the Chinese Academy of Sciences, and will not be listed here one by one) target fragments for specific PCR amplification, and use The genotyping test is carried out by conventional genotyping methods, and the genotyping test results related to tobacco and alcohol damage are obtained.

[0056] Step 3: Active H...

Embodiment 3

[0058] Embodiment 3. Active Health Service Series III-Comprehensive Prevention Standard Type I Service

[0059] Step 1: Sampling

[0060] The subjects were consulted before the service, and the subjects signed the informed consent form, and filled out the dietary and living habits questionnaire. The sampling process is the same as in Example 1.

[0061] Step 2: Genotyping Assay Processing

[0062] The DNA extraction process was the same as in Example 1. For atherosclerosis, hypertension, coronary heart disease, cerebral infarction, cerebral hemorrhage, diabetes, obesity, hyperlipidemia; bronchial asthma, ulcerative colitis, hyperthyroidism, senile dementia, osteoporosis, cholelithiasis, Gout, lung cancer, liver cancer, esophageal cancer, gastric cancer, colorectal cancer, nasopharyngeal cancer, thyroid cancer, kidney cancer, bladder cancer, leukemia, prostate cancer and other diseases; improve vitamin utilization, folic acid metabolism, antioxidant capacity, anti-aging, De...

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PUM

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Abstract

A method of using gene detection technique to provide active health service includes confirming gene polymorphism site carrier type of tested person by detecting phenotypic correlation gene polymorphism, confirming health genetic factor, forwarding personalized health guide and pharmacy report and gene typing detection report to tested person by using genetic factor as base and combining said base with investigation paper and body detection information of tested person.

Description

technical field [0001] The present invention relates to the fields of molecular biology and medicine, more specifically, the present invention relates to gene detection and analysis technology and the use of gene detection technology to provide services for human health, including biological sample DNA collection, extraction, analysis, positioning, guiding people to take active health care, etc. service, and the operating system to complete the service. Background technique [0002] Genetic detection and analysis technology has rapidly become an important tool for predicting human disease and health. Gene technology can correlate human health status with physiological diseases, genetic mutation factors, disease tendency and status, etc. Genetic factor mutations caused by base insertions, deletions, and mismatches in DNA sequences, as well as up-and-down regulation of individual DNA expressions, are all biological information related to health status and disease mechanisms. ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G06Q10/00G06Q50/00G06F19/00G06F19/10G06Q50/22
Inventor 冯哲民邹祖烨
Owner XINBAXIANG SHANGHAI MOLECULAR MEDICAL TECH SHANGHAI
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