O-aminoanisole electrochemical synthesis method

Abstract

Provided is an electrochemical synthetic method of ortho-anisidine, which includes four steps that firstly the method needs to be accomplished in an two-chamber electrolysis bath which is separated by employing a cation-exchange membrane, a copper sheet is taken as a negative electrode, a ruthenium net is taken as a positive electrode, a saturated calomel electrode is taken as a reference electrode, the negative electrode and the reference electrode are installed inside a cathode chamber of the electrolysis bath, and the positive electrode is installed inside an anode chamber of the electrolysis bath. Secondly methanol is taken as solvent, sulphuric acid is taken as supporting electrolyte, ortho-nitroanisole is taken as electrolytic reaction substrate, the solvent and solution of the supporting electrolyte are injected into the cathode chamber and the anode chamber, and the electrolytic reaction substrate is injected into the cathode chamber. Thirdly the electrolyzation is performed under the condition of normal temperature and pressure and the condition that the negative electrode is added with a certain constant voltage relative to the reference electrode, the voltage value of the constant voltage is between -0.6 to -1.0V. Fourthly after the electrolyzation is finished, the electrolyte is post-processed to prepare the product of the ortho-anisidine with the production ratio between 19.1-53.4%. The method has the advantages of simple requirement, mild reaction conditions, easy preparation of the electrodes, low price, small pollution in the process of reaction and the like, which is a greening production line.

Description

technical field [0001] The invention relates to an electrochemical synthesis method of o-aminoanisole, to be precise, relates to a method for preparing anthraniloanisole by electrolytic reduction of o-nitroanisole, and belongs to the technical field of electrochemistry. technical background [0002] Anisole, also known as o-methoxyaniline, o-anisidine, molecular formula C 7 h 9 NO, light yellow oily liquid, melting point 5°C, boiling point 225°C, miscible with ethanol and ether, insoluble in water. Anthranil is an important fine chemical intermediate, which is often used as an organic chemical raw material in industries such as medicine, dyes, and spices. In the pharmaceutical industry, it is used to prepare guaiacol, anlipine, wheezing, zhiakeer and Antenuoxin, etc. In the dye industry, it is used to prepare azo dyes, ice dyes, naphthol AS-OL, etc. In the food industry, it is used to prepare vanillin, rosin, etc. [0003] The traditional production method of o-aminoani...

AI Technical Summary

Problems solved by technology

[0004] The traditional synthesis method of anthranilic ether either uses expensive noble metal catalysts, or produces a large amount of waste during the reaction process, or requires harsh reaction conditions. Therefore, the traditional production method has no great development prospects