Plant capsule with cellulose vitriolate of soda as principal raw material and preparation method

Abstract

The invention discloses a plant capsule with cellulose sodium sulfate as main material and the preparation method, comprising the following steps: 1) put gelling agent with weight percentage concentration ranging from 1 percent to 6 percent and coagulant aid with weight percentage concentration ranging from 0.1 percent to 5 percent into water, stir, heat to 80 DEG C to 100 DEG C until totally dissolved; 2) then add cellulose sodium sulfate with weight percentage concentration ranging from 1 percent to 15 percent and plasticizer with weight percentage concentration ranging from 0.1 percent to6 percent, stir until totally dissolved and get glue solution; 3) reduce pressure and remove the bubble of the glue solution in 60 DEG C to 70 DEG C for 1 to 9 hours and keep the glue solution at 35 DEG C to 60 DEG C, dip the capsule preparing template into the feed liquid and mold the template by digging method to get the capsule; 4) dry the capsule in 30 DEG C to 40 DEG C for 24 to 72 hours, cut, remove the shell, put in order and prepare to get the capsule. The preparing method has the advantages of simple preparing process, strong controllability and the capsule has the property of low water content, facilitating protecting drugs in the capsule, not easy to be fragile in low temperature and low humidity, safer and not easily being polluted, and thus a wide application in pharmacy, food health products and other fields.

Description

technical field [0001] The invention relates to a plant capsule with cellulose sodium sulfate as the main raw material and a preparation method thereof. Background technique [0002] The traditional capsules used today were first invented by French pharmacist Mothes in 1833. After more than 170 years of development, capsules have been widely used in the pharmaceutical industry and health care products industry. It is estimated that tens of trillions of capsules are produced worldwide every year. grain. [0003] At present, the main raw material for the production of capsules is gelatin. Gelatin is a product obtained by boiling bones or skins of cattle, sheep, and pigs. Such gelatin capsules prepared from animal sources have many limitations. First, since the 1990s, "mad cow disease" has successively occurred in European countries such as Britain, France, and the Netherlands (it is reported that Japan has also found mad cow disease cattle), so some countries have strict re...

AI Technical Summary

Problems solved by technology

This gelatin capsule prepared from animal sources has many limitations

First, since the 1990s, "mad cow disease" has successively occurred in European countries such as Britain, France, and the Netherlands (it is reported that Japan has also found mad cow disease cattle), so some countries have strict regulations on beef and cattle related by-products (gelatin is also one of them). There is a greater sense of distrust; second, Buddhists, Muslims and vegetarians also have resistance to gelatin capsules produced from animal raw materials; third, capsules made of gelatin as the main raw material are Its water content is strictly required. When the water content is low, the brittleness of the capsule will increase, which is not conducive to the filling of the drug. Especially when the filling is a hygroscopic component, the water in the capsule shell is easily absorbed by the drug, making the capsule during storage. It is easy to crack and break in the medium, which seriously affects the product quality; Fourth, the gelatin capsule shell needs to be stored in a constant temperature and humidity environment. If the temperature is too high, it will soften and deform, and if the temperature is too low, it will be brittle.