2 results about "Cellulose sulfate" patented technology

The present application relates to the technical field of artificial implant medical device surface modification and middle ear hearing reconstruction, and discloses a processing method for enhancing the fixing stability of an artificial auditory ossicle prosthesis, the prosthesis and application. The method comprises the following steps: after the surface of the auditory ossicle prosthesis in contact with the middle ear tissue is cleaned, a polydopamine layer is formed in a basic dopamine solution, then gelatin, hyaluronic acid or cellulose sulfate is connected to the surface of the polydopamine layer through a carbodiimide activation system to form a viscous functional layer, and the dry sponge-like structure is obtained through freeze-drying. The functional layer can quickly rehydrate and restore the adhesion state after contacting with human blood or tissue fluid, thereby improving the fixing stability of the artificial auditory ossicle prosthesis in the initial implantation stage and reducing the risk of displacement or dislocation.

The present invention relates to a production method of an inactivated SARS-CoV-2 vaccine, the method including: a step of bringing a SARS-CoV-2 containing solution or an inactivated SARS-CoV-2 containing solution into contact with a cellulose sulfate ester gel at a pH of 8 or more and 10 or less to adsorb the SARS-CoV-2 or the inactivated SARS-CoV-2 to the gel; then removing impurities; and then eluting and recovering the SARS-CoV-2 or the inactivated SARS-CoV-2.