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Magnesium alloy bone surgery internal fixation and implantation material

An implant material, magnesium alloy technology, applied in the field of magnesium alloy internal fixation and implant materials, can solve problems such as unsatisfactory performance, achieve the effects of reducing stress shielding effect, facilitating healing, and improving surface biological activity

Inactive Publication Date: 2008-09-17
BEIJING ALLGENS MEDICAL SCI & TECH +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The comprehensive performance of magnesium alloy is very suitable for the above-mentioned implant materials, but the performance of magnesium alloy materials produced on the market is not very satisfactory as medical internal fixation and implant materials, and is suitable for nail-plate systems, intramedullary nail systems, etc. Magnesium alloys have almost no

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0032] The magnesium-zinc-calcium alloy is used as the bone plate and bone nail or intramedullary nail material, and its weight percentage is composed of: zinc content is 5%; calcium content is 3%, and the rest is magnesium and unavoidable impurities. The tensile strength of the bone plate and the bone nail or the intramedullary nail is 150MPa, the yield strength is 120MPa, and the elongation at break is 5%. Soak the osteosynthesis plate and bone nail or intramedullary nail in 0.9% NaCl solution for one month, and calculate its degradation rate as 0.40mm / year according to the weight loss of the sample.

Embodiment 2

[0034] Magnesium-zinc-calcium-aluminum alloy is used as bone plate and bone nail or intramedullary nail material, and its weight percentage is composed of: the content of zinc is 3%, the content of calcium is 1%, and the content of aluminum is 4%; the rest is magnesium and cannot Avoid impurities. The tensile strength of the bone plate and the bone nail or the intramedullary nail is 250MPa, the yield strength is 230MPa, and the elongation at break is 9%. Soak the bone plate and bone nail or intramedullary nail in 0.9% NaCl solution for one month, and calculate the degradation rate of 0.25mm / year according to the weight loss of the sample.

Embodiment 3

[0036] Magnesium-zinc-calcium-rare earth alloy is used as bone plate and bone nail or intramedullary nail material, and its weight percentage is composed of: 2% zinc; 2% calcium; 1% neodymium; 3% niobium, and the rest are magnesium and unavoidable impurities. The tensile strength of the bone plate and the bone nail or the intramedullary nail is 200MPa, the yield strength is 180MPa, and the elongation at break is 8%. Soak the bone plate and bone nail or intramedullary nail in 0.9% NaCl solution for one month, and calculate the degradation rate of 0.20mm / year according to the weight loss of the sample.

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Abstract

The invention relates to a magnesium alloy internal fixation and implant material used in orthopedic surgeries, which is characterized in that the pure magnesium is used as the substrate, and calcium and zinc elements are added into the pure magnesium; wherein, the zinc accounts for 2-5%, and the calcium accounts for 1-3%. The magnesium alloy internal fixation and implant material used in orthopedic surgeries has the advantages of enjoying favorable biocompatibility, excellent mechanical property and controllable degradation rate, and meeting the demands for internal fixation and implant materials in orthopedic surgeries, thus being particularly suitable for screw plate systems and intramedullary pin systems.

Description

technical field [0001] The invention belongs to the field of biomedical materials, and specifically relates to the application of degradable magnesium alloy materials as bone surgery internal fixation and implant materials in bone trauma surgery and plastic reconstruction surgery, in particular to nail-plate systems, intramedullary Magnesium alloy internal fixation and implant materials for nail systems, etc. Background technique [0002] At present, the orthopedic internal fixation and implant materials used clinically are mainly made of stainless steel and titanium alloy materials. These materials cannot be absorbed and degraded in the body. Body function or bone healing. Therefore, when the bone is healed, most of the internal fixation or implant materials need to be taken out by secondary surgery, which not only increases the financial burden of the patient, but also increases the physical pain. At the same time, because the mechanical strength and density of the alloy...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61L27/04A61L31/02A61F5/01
Inventor 崔菡焦延鹏张余尹庆水王本学
Owner BEIJING ALLGENS MEDICAL SCI & TECH
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