Process for producing medical endotracheal tube with anti-bacterial adherence function and photoinduction disinfection function

Abstract

The invention provides a method for preparing a medical tracheal catheter capable of resisting bacterial adhesion and performing photo-induced sterilization. The method includes the preparation of TiO2 and a composite oxide coating liquid, and the film forming of a coating liquid on the inner surface of a PVC tracheal catheter. Specifically, the preparation method comprises the following steps: a suspension coating liquid is formed by mixing and dissolving an organic polymer binder in a crystalline state semiconductor oxide sol or a suspension characterized by photo-catalytic activity; and then a thin film with the advantages of high bonding strength, good anti-bacterial performance and excellent lighting sterilization performance is formed by plating the coating liquid uniformly on the surface of the inner wall of a tracheal catheter with a modified surface. The preparation technology can enable the medical PVC tracheal catheter to resist bacterial adhesion and to retain the effectiveness and stability of the photo-induced sterilization performance for a long period.

Description

technical field

[0001] The invention belongs to the field of medical biomaterials, and more specifically relates to a technology for loading a photocatalytic film with anti-bacterial adhesion and light-induced bactericidal properties on the inner wall surface of a medical PVC tracheal catheter. Background technique

[0002] With the continuous development of medicine, the application of biomaterials has become increasingly common, and the biomaterial-associated infection caused by bacteria adhering to the surface of biomaterials to form a biofilm has become an increasingly important problem. The wide application of artificial organs and components of polymer materials in medical treatment has increased the ways for bacteria to invade the human body. Among them, the respiratory infection caused by PVC endotracheal tube is a typical example. Long-term placement of polyvinyl chloride (PVC) tracheal tubes is an important cause of nosocomial respiratory infections, resulting in ...