Ozagrel sodium microballoon lyophilized preparation and preparation method thereof

A technology of ozagrel sodium and freeze-dried agent, which is applied in the field of medicine, can solve problems such as short storage time, clarity problems, suspended particles, etc., and achieve the effect of simple process, low production cost and good targeting
CN101444491BInactive Publication Date: 2010-04-14HAINAN MEIDA PHARMA
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
HAINAN MEIDA PHARMA
Publication Date
2010-04-14
Estimated Expiration
Not applicable · inactive patent

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Abstract

The invention relates to an ozagrel sodium microballoon lyophilized preparation and a preparation method thereof. The ozagrel sodium microballoon lyophilized preparation of the invention mainly includes the following components by weight part: 20-80 parts of ozagrel sodium, 50-150 parts of chitosan, 40-100 parts of polyvinyl alcohol, and 50-300 parts of lyophilization protective agent. The ozagrelsodium microballoon lyophilized preparation of the invention has the advantages of good stability and solubility, small grain diameter of lipidosome after hydration, strong targeting property, low production cost and the like.
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Description

technical field

[0001] The invention relates to a ozagrel sodium microsphere freeze-dried agent and a preparation method thereof, belonging to the technical field of medicine. Background technique

[0002] Ozagrel (English name: ozagrel) is a highly effective and selective inhibitor of thromboxane synthase, which inhibits thromboxane A2 (TXA 2 ) synthesis and promotion of prostacyclin (PGI 2 ), which has the effects of anti-platelet aggregation, reducing blood viscosity, promoting thrombus decomposition and dilating blood vessels. Therefore, it is especially suitable for inhibiting cerebral vasospasm, increasing cerebral blood flow, improving microcirculation disorders and abnormal energy metabolism in the brain, and improving cerebral ischemic symptoms and cerebral thrombosis (acute stage) patients after subarachnoid hemorrhage. movement disorders. Clinically, it is widely used in the treatment of acute thrombotic cerebral infarction and the movement disorder accompanied...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
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