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Soluble absorbable hemostasia products based on modified viscose fiber and preparation method thereof

A viscose fiber and absorbent technology, applied in the field of hemostatic products based on modified viscose fiber and its preparation, can solve the problems of insufficient viscosity, poor adsorption function, inconvenient clinical use, etc., and achieve fast absorption by the body and speed of hemostasis. Faster and faster wound healing

Inactive Publication Date: 2009-06-10
张博
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] The purpose of the present invention is to solve the problem that the soluble hemostatic gauze has poor adsorption function, insufficient viscosity and inconvenient clinical use in the prior art

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0016] Embodiment 1, preparation of the soluble and absorbable hemostatic product based on modified viscose fiber

[0017] Prepare an ethanol solution with a concentration of 70-95%, add sodium hydroxide solution, raise the temperature to 35-85°C, stir evenly, add viscose fiber, and carry out dynamic chemical bonding under the condition of stirring or ultrasonic vibration for 0.5-12 hours After taking out, continue to add monochloroacetic acid solution in above medicinal solution, semi-finished product is put into medicinal solution, wherein: the weight ratio of ethanol solution, sodium hydroxide solution, viscose fiber, chloroacetic acid solution is: (0.2-10) Gram: (1-8) gram: (0.1-6) gram: (0.1-8) gram, continue the dynamic chemical combination at 35-85°C for 0.5-12 hours, take it out, adjust the pH, and dry it.

Embodiment 2

[0018] Example 2, Preparation of Amino Acid-Containing Soluble Absorbable Hemostatic Products Based on Modified Viscose Fiber

[0019] Prepare an ethanol solution with a concentration of 70-95%, add disodium hydrogen phosphate, sodium hydrogen phosphate, and then add amino acid drugs, raise the temperature to 30-70°C, stir evenly, add the modified viscose prepared in Example 1 The fibers are dynamically chemically bonded under the condition of stirring or ultrasonic vibration for 6-12 hours and then taken out, and polyethylene glycol, Tween-80, simethicone, and sodium carboxymethylcellulose are added to the above liquid medicine. Put the above-mentioned gauze into the liquid medicine, continue the dynamic chemical combination at 35-85°C for 6-12 hours, take it out, and dry it with steam to get the finished product.

Embodiment 3

[0020] Embodiment 3, preparation of viscose fiber antibacterial and pain-relieving soluble absorbable hemostatic product

[0021] Concentration is 70-95% ethanol solution, add disodium hydrogen phosphate, sodium alginate, carbomer, then add antibacterial drug and analgesic drug, raise the temperature to 35-85 ℃, stir evenly, add embodiment 1 The prepared modified viscose fiber is taken out after dynamic chemical bonding under the condition of stirring or ultrasonic vibration for 0.5-12 hours, and polyethylene glycol, Tween-80, simethicone, Sodium carboxymethyl cellulose, put the semi-finished product into the liquid medicine, continue the dynamic chemical combination at 35-85°C for 0.5-12 hours, take it out, and dry it with steam to get the finished product.

[0022] Beneficial effect:

[0023] Product of the present invention compares with prior art product:

[0024] 1. The hemostatic product made of modified viscose fiber has better anti-adhesive and hemostatic effects on ...

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PUM

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Abstract

The invention provides a soluble absorbable hemostasis product based on modified novamat and a preparing method. The method includes steps as follows: preparing gasohol solution with concentration of 60-95%, then adding into sodium hydroxide solution, increasing temperature to 10-85 degrees Celsius, stirring well, adding into novamat, processing dynamic chemical combination within 0.5-12 hours in condition of stirring or supersonic vibrating, then taking out and obtaining a modified novamat semi-finished product, adding chloroacetic acid solution into the medical solution as above continuously, putting the semi-finished product into the medical solution, processing dynamic chemical combination within 0.5-12 hours under 10-85 degree Celsius continuously, taking out, (or adding or not adding antibacterial agent and pain medication lt; antibacterial agent is ciprofloxacin, povidone iodine or the compound; pain medication is benzocaine, lidocaine or the compound gt), adjusting PH value and drying.

Description

technical field [0001] The invention relates to the technical field of medical materials, in particular to a hemostatic product based on modified viscose fiber and a preparation method thereof. Background of the invention [0002] Viscose fiber was invented by Americans Cross and Bevan in 1981, and it is the earliest man-made fiber to realize industrial production. For more than 100 years, viscose fiber has been favored by consumers for a long time due to its comfortable wearing performance, and its output has always been the largest among cellulose fibers. It is widely used in clothing industry, industry, agriculture, transportation, medical and health, Many fields of aerospace and national defense. The modification of viscose fiber is a research hotspot in recent years and many new products have been developed. [0003] Medical gauze is generally made of all-round fiber light spinning, weaving, degreasing, bleaching, drying, and disinfection for use by medical and health...

Claims

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Application Information

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IPC IPC(8): A61L15/28
Inventor 张博
Owner 张博
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