Method for improving ribose purity

Abstract

The invention discloses a method for improving the purity of ribose, which relates to a technical process for purifying ribose. The method improves the proportion of epimers of ribose produced by using gum sugar, uses molybdic acid as a catalyst, adds boric acid compounds into a reaction system, uses a spectrum separation technology to remove impurities such as xylose and lyxose in ribose liquid, and crystallizes the obtained high-purity ribose liquid to prepare ribose crystal. The process comprises: (1) material mixing and hot melting; (2) filtration and evaporation; (3) iron exchange; (4) separation; and (5) crystallization. The method improves the rate of ribose conversion from gum sugar by improving the proportion of the epimers and increases the purity of the ribose liquid to more than 90 percent by using the spectrum separation technology for separating azasugar and prepares ribose crystal with a purity of more than 99.8 percent. The method has the advantages that the purification process is simple, the production period is short and the obtained ribose liquid is high in purity, low in impurity content and easy to crystallize, and so on.

Description

Technical field [0001] The invention belongs to the technical field of functional sugar production and relates to a process method for ribose purification. Background technique [0002] The industrial production of ribose is generally produced by the supplemental fermentation method. The transketolase-deficient Bacillus subtilis strain is subjected to mutagenesis and breeding, and then it is put into the slant medium, the seed liquid medium and the fermentation medium at a time. During the fermentation and cultivation period, the glucose feed liquid and the ammonium sulfate feed liquid are fed by the intermittent decreasing flow method and the intermittent quantitative flow method to obtain ribose. The process is complicated and the production time is long. It has also been reported that ribose is produced by epimerization of arabinose, but the purity of the ribose liquid produced by this method is low, generally only 60%, and the solution contains xylose, lyxose and other mixed ...

AI Technical Summary

Problems solved by technology

[0003] In order to overcome the deficiencies of the prior art, the present invention provides a method for improving the purity of ribose to solve the complex process of the prior art, long production time, low purity of the produced ribose solution, high miscellaneous sugar content, difficult crystallization of the product, and difficult Obtaining high-purity ribose products and other issues